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WIREs Syst Biol Med
Impact Factor: 3.709

Physiology

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The mammalian mycobiome: A complex system in a dynamic relationship with the host

Advanced Review
Ghee Chuan Lai, Tze Guan Tan, Norman Pavelka
Published Online: Sep 25 2018
DOI:10.1002/wsbm.1438

Abstract Full article on Wiley Online Library:   HTML | PDF
Committing the primordial germ cell: An updated molecular perspective

Advanced Review
Haihan Tan, Wee‐Wei Tee
Published Online: Sep 18 2018
DOI:10.1002/wsbm.1436

Abstract Full article on Wiley Online Library:   HTML | PDF
Quantitative systems models illuminate arrhythmia mechanisms in heart failure: Role of the Na + ‐Ca 2+ ‐Ca 2+ /calmodulin‐dependent protein kinase II‐reactive oxygen species feedback

Focus Article
Stefano Morotti, Eleonora Grandi
Published Online: Jul 17 2018
DOI:10.1002/wsbm.1434

Abstract Full article on Wiley Online Library:   HTML | PDF
Cell cycle regulation of folate‐mediated one‐carbon metabolism

Advanced Review
Xu Lan, Martha S. Field, Patrick J. Stover
Published Online: Jun 11 2018
DOI:10.1002/wsbm.1426

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems approaches to optimizing deep brain stimulation therapies in Parkinson’s disease

Overview
Sabato Santaniello, John T. Gale, Sridevi V. Sarma
Published Online: Mar 20 2018
DOI:10.1002/wsbm.1421

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems analysis of dilated cardiomyopathy in the next generation sequencing era

Focus Article
Magdalena Harakalova, Folkert W. Asselbergs
Published Online: Feb 27 2018
DOI:10.1002/wsbm.1419

Abstract Full article on Wiley Online Library:   HTML | PDF
Chromatin modifications in metabolic disease: Potential mediators of long‐term disease risk

Focus Article
Kevin R. Costello, Dustin E. Schones
Published Online: Jan 25 2018
DOI:10.1002/wsbm.1416

Abstract Full article on Wiley Online Library:   HTML | PDF
Human microbiota, blood group antigens, and disease

Advanced Review
D. Rose Ewald, Susan C.J. Sumner
Published Online: Jan 09 2018
DOI:10.1002/wsbm.1413

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of oxygen homeostasis

Advanced Review
Debangshu Samanta, Nanduri R. Prabhakar, Gregg L. Semenza
Published Online: Feb 21 2017
DOI:10.1002/wsbm.1382

Abstract Full article on Wiley Online Library:   HTML | PDF
Computational models of the neural control of breathing

Advanced Review
Yaroslav I. Molkov, Jonathan E. Rubin, Ilya A. Rybak, Jeffrey C. Smith
Published Online: Dec 23 2016
DOI:10.1002/wsbm.1371

Abstract Full article on Wiley Online Library:   HTML | PDF
Cancer and inflammation

Overview
Lance L. Munn
Published Online: Dec 12 2016
DOI:10.1002/wsbm.1370

Abstract Full article on Wiley Online Library:   HTML | PDF
Mathematical modeling of the female reproductive system: from oocyte to delivery

Overview
Alys R Clark, Jennifer A Kruger
Published Online: Sep 09 2016
DOI:10.1002/wsbm.1353

Abstract Full article on Wiley Online Library:   HTML | PDF
Network dynamics: quantitative analysis of complex behavior in metabolism, organelles, and cells, from experiments to models and back

Advanced Review
Felix T. Kurz, Jackelyn M. Kembro, Ana G. Flesia, Antonis A. Armoundas, Sonia Cortassa, Miguel A. Aon, David Lloyd
Published Online: Sep 07 2016
DOI:10.1002/wsbm.1352

Abstract Full article on Wiley Online Library:   HTML | PDF
In silico bone mechanobiology: modeling a multifaceted biological system

Advanced Review
Mario Giorgi, Stefaan W. Verbruggen, Damien Lacroix
Published Online: Sep 07 2016
DOI:10.1002/wsbm.1356

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems physiology of the airways in health and obstructive pulmonary disease

Advanced Review
Jason H.T. Bates
Published Online: Jun 24 2016
DOI:10.1002/wsbm.1347

Abstract Full article on Wiley Online Library:   HTML | PDF
Mitochondrial metabolic remodeling in response to genetic and environmental perturbations

Advanced Review
Kate E.R. Hollinshead, Daniel A. Tennant
Published Online: May 19 2016
DOI:10.1002/wsbm.1334

Abstract Full article on Wiley Online Library:   HTML | PDF
Adaptive resistance to antibiotics in bacteria: a systems biology perspective

Advanced Review
Santiago Sandoval‐Motta, Maximino Aldana
Published Online: Apr 21 2016
DOI:10.1002/wsbm.1335

Abstract Full article on Wiley Online Library:   HTML | PDF
Signaling via the NFκB system

Advanced Review
Simon Mitchell, Jesse Vargas, Alexander Hoffmann
Published Online: Mar 16 2016
DOI:10.1002/wsbm.1331

Abstract Full article on Wiley Online Library:   HTML | PDF
Dynamics of the mammalian cell cycle in physiological and pathological conditions

Focus Article
Claude Gérard, Albert Goldbeter
Published Online: Nov 27 2015
DOI:10.1002/wsbm.1325

Abstract Full article on Wiley Online Library:   HTML | PDF
The virtual intestine: in silico modeling of small intestinal electrophysiology and motility and the applications

Advanced Review
Peng Du, Niranchan Paskaranandavadivel, Timothy R. Angeli, Leo K. Cheng, Gregory O'Grady
Published Online: Nov 12 2015
DOI:10.1002/wsbm.1324

Abstract Full article on Wiley Online Library:   HTML | PDF
Measurement and modeling of coronary blood flow

Overview
Matthew D. Sinclair, Jack Lee, Andrew N. Cookson, Simone Rivolo, Eoin R. Hyde, Nicolas P. Smith
Published Online: Jun 30 2015
DOI:10.1002/wsbm.1309

Abstract Full article on Wiley Online Library:   HTML | PDF
Implementation of integral feedback control in biological systems

Advanced Review
Pramod R. Somvanshi, Anilkumar K. Patel, Sharad Bhartiya, K. V. Venkatesh
Published Online: Jun 02 2015
DOI:10.1002/wsbm.1307

Abstract Full article on Wiley Online Library:   HTML | PDF
The role of the microbiota in ageing: current state and perspectives

Focus Article
Denise B. Lynch, Ian B. Jeffery, Paul W. O'Toole
Published Online: Mar 16 2015
DOI:10.1002/wsbm.1293

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems engineering meets quantitative systems pharmacology: from low‐level targets to engaging the host defenses

Opinion
Ioannis P. Androulakis
Published Online: Mar 16 2015
DOI:10.1002/wsbm.1294

Abstract Full article on Wiley Online Library:   HTML | PDF
Experience‐sensitive epigenetic mechanisms, developmental plasticity, and the biological embedding of chronic disease risk

Overview
Vincent T. Cunliffe
Published Online: Feb 20 2015
DOI:10.1002/wsbm.1291

Abstract Full article on Wiley Online Library:   HTML | PDF
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