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WIREs Syst Biol Med
Impact Factor: 3.542

Physiology

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Calibration of ionic and cellular cardiac electrophysiology models

Advanced Review
Dominic G. Whittaker, Michael Clerx, Chon Lok Lei, David J. Christini, Gary R. Mirams
Published Online: Feb 21 2020
DOI:10.1002/wsbm.1482

Abstract Full article on Wiley Online Library:   HTML | PDF
Glucose transporter 1 in rheumatoid arthritis and autoimmunity

Advanced Review
Ekaterina Zezina, Oezen Sercan‐Alp, Matthias Herrmann, Nadine Biesemann
Published Online: Feb 21 2020
DOI:10.1002/wsbm.1483

Abstract Full article on Wiley Online Library:   HTML | PDF
Single‐cell analysis of CD8 T lymphocyte diversity during adaptive immunity

Focus Article
Janilyn Arsenio
Published Online: Dec 26 2019
DOI:10.1002/wsbm.1475

Abstract Full article on Wiley Online Library:   HTML | PDF
Functional genomic approaches to elucidate the role of enhancers during development

Advanced Review
Genevieve E. Ryan, Emma K. Farley
Published Online: Dec 05 2019
DOI:10.1002/wsbm.1467

Abstract Full article on Wiley Online Library:   HTML | PDF
Network architecture and regulatory logic in neural crest development

Focus Article
Austin S. Hovland, Megan Rothstein, Marcos Simoes‐Costa
Published Online: Nov 08 2019
DOI:10.1002/wsbm.1468

Abstract Full article on Wiley Online Library:   HTML | PDF
Skeletal muscle: A review of molecular structure and function, in health and disease

Advanced Review
Kavitha Mukund, Shankar Subramaniam
Published Online: Aug 13 2019
DOI:10.1002/wsbm.1462

Abstract Full article on Wiley Online Library:   HTML | PDF
Multiscale modeling of the neuromuscular system: Coupling neurophysiology and skeletal muscle mechanics

Advanced Review
Oliver Röhrle, Utku Ş. Yavuz, Thomas Klotz, Francesco Negro, Thomas Heidlauf
Published Online: Jun 24 2019
DOI:10.1002/wsbm.1457

Abstract Full article on Wiley Online Library:   HTML | PDF
Neutrophils in innate immunity and systems biology‐level approaches

UPDATE
Viktoria Rungelrath, Scott D. Kobayashi, Frank R. DeLeo
Published Online: Jun 20 2019
DOI:10.1002/wsbm.1458

Abstract Full article on Wiley Online Library:   HTML | PDF
Circadian rhythms and proteomics: It's all about posttranslational modifications!

Focus Article
Daniel Mauvoisin
Published Online: Apr 29 2019
DOI:10.1002/wsbm.1450

Abstract Full article on Wiley Online Library:   HTML | PDF
Essential contributions of enhancer genomic regulatory elements to microglial cell identity and functions

Focus Article
André Machado Xavier, Sarah Belhocine, David Gosselin
Published Online: Apr 23 2019
DOI:10.1002/wsbm.1449

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of robustness and homeostatic mechanisms

Overview
H. Frederik Nijhout, Janet A. Best, Michael C. Reed
Published Online: Oct 29 2018
DOI:10.1002/wsbm.1440

Abstract Full article on Wiley Online Library:   HTML | PDF
Mathematical modeling of circadian rhythms

Focus Article
Ameneh Asgari‐Targhi, Elizabeth B. Klerman
Published Online: Oct 17 2018
DOI:10.1002/wsbm.1439

Abstract Full article on Wiley Online Library:   HTML | PDF
The mammalian mycobiome: A complex system in a dynamic relationship with the host

Advanced Review
Ghee Chuan Lai, Tze Guan Tan, Norman Pavelka
Published Online: Sep 25 2018
DOI:10.1002/wsbm.1438

Abstract Full article on Wiley Online Library:   HTML | PDF
Committing the primordial germ cell: An updated molecular perspective

Advanced Review
Haihan Tan, Wee‐Wei Tee
Published Online: Sep 17 2018
DOI:10.1002/wsbm.1436

Abstract Full article on Wiley Online Library:   HTML | PDF
Quantitative systems models illuminate arrhythmia mechanisms in heart failure: Role of the Na+‐Ca2+‐Ca2+/calmodulin‐dependent protein kinase II‐reactive oxygen species feedback

Focus Article
Stefano Morotti, Eleonora Grandi
Published Online: Jul 17 2018
DOI:10.1002/wsbm.1434

Abstract Full article on Wiley Online Library:   HTML | PDF
Cell cycle regulation of folate‐mediated one‐carbon metabolism

Advanced Review
Patrick J. Stover, Martha S. Field, Xu Lan
Published Online: Jun 11 2018
DOI:10.1002/wsbm.1426

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems approaches to optimizing deep brain stimulation therapies in Parkinson’s disease

Overview
Sabato Santaniello, John T. Gale, Sridevi V. Sarma
Published Online: Mar 20 2018
DOI:10.1002/wsbm.1421

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems analysis of dilated cardiomyopathy in the next generation sequencing era

Focus Article
Folkert W. Asselbergs, Magdalena Harakalova
Published Online: Feb 27 2018
DOI:10.1002/wsbm.1419

Abstract Full article on Wiley Online Library:   HTML | PDF
Chromatin modifications in metabolic disease: Potential mediators of long‐term disease risk

Focus Article
Dustin E. Schones, Kevin R. Costello
Published Online: Jan 25 2018
DOI:10.1002/wsbm.1416

Abstract Full article on Wiley Online Library:   HTML | PDF
Human microbiota, blood group antigens, and disease

Advanced Review
D. Rose Ewald, Susan C.J. Sumner
Published Online: Jan 09 2018
DOI:10.1002/wsbm.1413

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of oxygen homeostasis

Advanced Review
Gregg L. Semenza, Nanduri R. Prabhakar, Debangshu Samanta
Published Online: Feb 21 2017
DOI:10.1002/wsbm.1382

Abstract Full article on Wiley Online Library:   HTML | PDF
Traditional and novel tools to probe the mitochondrial metabolism in health and disease

Advanced Review
Yanfei Zhang, José L. Avalos
Published Online: Jan 09 2017
DOI:10.1002/wsbm.1373

Abstract Full article on Wiley Online Library:   HTML | PDF
Computational models of the neural control of breathing

Advanced Review
Yaroslav I. Molkov, Jonathan E. Rubin, Ilya A. Rybak, Jeffrey C. Smith
Published Online: Dec 23 2016
DOI:10.1002/wsbm.1371

Abstract Full article on Wiley Online Library:   HTML | PDF
Cancer and inflammation

Overview
Lance L. Munn
Published Online: Dec 12 2016
DOI:10.1002/wsbm.1370

Abstract Full article on Wiley Online Library:   HTML | PDF
Mathematical modeling of the female reproductive system: from oocyte to delivery

Overview
Alys R Clark, Jennifer A Kruger
Published Online: Sep 09 2016
DOI:10.1002/wsbm.1353

Abstract Full article on Wiley Online Library:   HTML | PDF
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