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WIREs Syst Biol Med
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Biological Mechanisms

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Neutrophils in innate immunity and systems biology‐level approaches

UPDATE
Viktoria Rungelrath, Scott D. Kobayashi, Frank R. DeLeo
Published Online: Jun 20 2019
DOI:10.1002/wsbm.1458

Abstract Full article on Wiley Online Library:   HTML | PDF
IL7 receptor signaling in T cells: A mathematical modeling perspective

Overview
Jung‐Hyun Park, Adam T. Waickman, Joseph Reynolds, Mario Castro, Carmen Molina‐París
Published Online: May 28 2019
DOI:10.1002/wsbm.1447

Abstract Full article on Wiley Online Library:   HTML | PDF
Circadian rhythms and proteomics: It's all about posttranslational modifications!

Focus Article
Daniel Mauvoisin
Published Online: Apr 29 2019
DOI:10.1002/wsbm.1450

Abstract Full article on Wiley Online Library:   HTML | PDF
Essential contributions of enhancer genomic regulatory elements to microglial cell identity and functions

Focus Article
André Machado Xavier, Sarah Belhocine, David Gosselin
Published Online: Apr 23 2019
DOI:10.1002/wsbm.1449

Abstract Full article on Wiley Online Library:   HTML | PDF
Calcium signals that determine vascular resistance

Focus Article
Matteo Ottolini, Kwangseok Hong, Swapnil K. Sonkusare
Published Online: Mar 18 2019
DOI:10.1002/wsbm.1448

Abstract Full article on Wiley Online Library:   HTML | PDF
Towards multiscale modeling of the CD8+ T cell response to viral infections

Advanced Review
Subhasish Baral, Rubesh Raja, Pramita Sen, Narendra M. Dixit
Published Online: Feb 27 2019
DOI:10.1002/wsbm.1446

Abstract Full article on Wiley Online Library:   HTML | PDF
Integrating molecular networks with genetic variant interpretation for precision medicine

Overview
Emidio Capriotti, Kivilcim Ozturk, Hannah Carter
Published Online: Dec 12 2018
DOI:10.1002/wsbm.1443

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of robustness and homeostatic mechanisms

Overview
H. Frederik Nijhout, Janet A. Best, Michael C. Reed
Published Online: Oct 29 2018
DOI:10.1002/wsbm.1440

Abstract Full article on Wiley Online Library:   HTML | PDF
Context‐dependent regulation of receptor tyrosine kinases: Insights from systems biology approaches

Focus Article
Inez Lam, Christina M. Pickering, Feilim Mac Gabhann
Published Online: Sep 26 2018
DOI:10.1002/wsbm.1437

Abstract Full article on Wiley Online Library:   HTML | PDF
Committing the primordial germ cell: An updated molecular perspective

Advanced Review
Haihan Tan, Wee‐Wei Tee
Published Online: Sep 17 2018
DOI:10.1002/wsbm.1436

Abstract Full article on Wiley Online Library:   HTML | PDF
The mechanistic basis for chromatin regulation by pioneer transcription factors

Advanced Review
Makiko Iwafuchi‐Doi
Published Online: Jun 27 2018
DOI:10.1002/wsbm.1427

Abstract Full article on Wiley Online Library:   HTML | PDF
Cell cycle regulation of folate‐mediated one‐carbon metabolism

Advanced Review
Xu Lan, Martha S. Field, Patrick J. Stover
Published Online: Jun 11 2018
DOI:10.1002/wsbm.1426

Abstract Full article on Wiley Online Library:   HTML | PDF
Diversification of transcription factor–DNA interactions and the evolution of gene regulatory networks

Advanced Review
Julia M. Rogers, Martha L. Bulyk
Published Online: Apr 25 2018
DOI:10.1002/wsbm.1423

Abstract Full article on Wiley Online Library:   HTML | PDF
Mechanisms of Wnt signaling and control

Overview
Stephanie Grainger, Karl Willert
Published Online: Mar 30 2018
DOI:10.1002/wsbm.1422

Abstract Full article on Wiley Online Library:   HTML | PDF
Multiscale systems biology of trauma‐induced coagulopathy

Focus Article
Evan Tsiklidis, Carrie Sims, Talid Sinno, Scott L. Diamond
Published Online: Feb 27 2018
DOI:10.1002/wsbm.1418

Abstract Full article on Wiley Online Library:   HTML | PDF
Chromatin modifications in metabolic disease: Potential mediators of long‐term disease risk

Focus Article
Kevin R. Costello, Dustin E. Schones
Published Online: Jan 25 2018
DOI:10.1002/wsbm.1416

Abstract Full article on Wiley Online Library:   HTML | PDF
Genome‐scale metabolic models applied to human health and disease

Advanced Review
Daniel J Cook, Jens Nielsen
Published Online: Jun 23 2017
DOI:10.1002/wsbm.1393

Abstract Full article on Wiley Online Library:   HTML | PDF
The best models of metabolism

Advanced Review
Eberhard O. Voit
Published Online: May 19 2017
DOI:10.1002/wsbm.1391

Abstract Full article on Wiley Online Library:   HTML | PDF
Genome organization during the cell cycle: unity in division

Focus Article
Rosela Golloshi, Jacob T. Sanders, Rachel Patton McCord
Published Online: May 16 2017
DOI:10.1002/wsbm.1389

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of cellular membranes: a convergence with biophysics

Advanced Review
Morgan Chabanon, Jeanne C. Stachowiak, Padmini Rangamani
Published Online: May 05 2017
DOI:10.1002/wsbm.1386

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of oxygen homeostasis

Advanced Review
Debangshu Samanta, Nanduri R. Prabhakar, Gregg L. Semenza
Published Online: Feb 21 2017
DOI:10.1002/wsbm.1382

Abstract Full article on Wiley Online Library:   HTML | PDF
Physiological, metabolic and biotechnological features of extremely thermophilic microorganisms

Advanced Review
James A. Counts, Benjamin M. Zeldes, Laura L. Lee, Christopher T. Straub, Michael W.W. Adams, Robert M. Kelly
Published Online: Feb 16 2017
DOI:10.1002/wsbm.1377

Abstract Full article on Wiley Online Library:   HTML | PDF
Understanding the mTOR signaling pathway via mathematical modeling

Advanced Review
Nurgazy Sulaimanov, Martin Klose, Hauke Busch, Melanie Boerries
Published Online: Feb 10 2017
DOI:10.1002/wsbm.1379

Abstract Full article on Wiley Online Library:   HTML | PDF
Regulatory elements in molecular networks

Advanced Review
Ashley S. Doane, Olivier Elemento
Published Online: Jan 17 2017
DOI:10.1002/wsbm.1374

Abstract Full article on Wiley Online Library:   HTML | PDF
Traditional and novel tools to probe the mitochondrial metabolism in health and disease

Advanced Review
Yanfei Zhang, José L. Avalos
Published Online: Jan 09 2017
DOI:10.1002/wsbm.1373

Abstract Full article on Wiley Online Library:   HTML | PDF
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