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WIREs Syst Biol Med
Impact Factor: 2.385

Biological Mechanisms

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Metabolism in cancer metastasis: bioenergetics, biosynthesis, and beyond

Advanced Review
Shao Thing Teoh, Sophia Y. Lunt
Published Online: Oct 09 2017
DOI:10.1002/wsbm.1406

Abstract Full article on Wiley Online Library:   HTML | PDF
Small molecule signaling, regulation, and potential applications in cellular therapeutics

Advanced Review
Monica P. McNerney, Mark P. Styczynski
Published Online: Sep 28 2017
DOI:10.1002/wsbm.1405

Abstract Full article on Wiley Online Library:   HTML | PDF
Targeting epidermal growth factor receptor co‐dependent signaling pathways in glioblastoma

Opinion
Feng Liu, Paul S. Mischel
Published Online: Sep 11 2017
DOI:10.1002/wsbm.1398

Abstract Full article on Wiley Online Library:   HTML | PDF
Metabolic interactions in cancer: cellular metabolism at the interface between the microenvironment, the cancer cell phenotype and the epigenetic landscape

Advanced Review
Gianmarco Rinaldi, Matteo Rossi, Sarah‐Maria Fendt
Published Online: Aug 30 2017
DOI:10.1002/wsbm.1397

Abstract Full article on Wiley Online Library:   HTML | PDF
Crosstalk between transcription and metabolism: how much enzyme is enough for a cell?

Focus Article
Stefano Donati, Timur Sander, Hannes Link
Published Online: Aug 15 2017
DOI:10.1002/wsbm.1396

Abstract Full article on Wiley Online Library:   HTML | PDF
Stability analysis in spatial modeling of cell signaling

Primer
Michael C. Getz, Jasmine A. Nirody, Padmini Rangamani
Published Online: Aug 08 2017
DOI:10.1002/wsbm.1395

Abstract Full article on Wiley Online Library:   HTML | PDF
Genome‐scale metabolic models applied to human health and disease

Advanced Review
Daniel J Cook, Jens Nielsen
Published Online: Jun 23 2017
DOI:10.1002/wsbm.1393

Abstract Full article on Wiley Online Library:   HTML | PDF
The best models of metabolism

Advanced Review
Eberhard O. Voit
Published Online: May 19 2017
DOI:10.1002/wsbm.1391

Abstract Full article on Wiley Online Library:   HTML | PDF
Genome organization during the cell cycle: unity in division

Focus Article
Rosela Golloshi, Jacob T. Sanders, Rachel Patton McCord
Published Online: May 16 2017
DOI:10.1002/wsbm.1389

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of cellular membranes: a convergence with biophysics

Advanced Review
Morgan Chabanon, Jeanne C. Stachowiak, Padmini Rangamani
Published Online: May 05 2017
DOI:10.1002/wsbm.1386

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of oxygen homeostasis

Advanced Review
Debangshu Samanta, Nanduri R. Prabhakar, Gregg L. Semenza
Published Online: Feb 21 2017
DOI:10.1002/wsbm.1382

Abstract Full article on Wiley Online Library:   HTML | PDF
Physiological, metabolic and biotechnological features of extremely thermophilic microorganisms

Advanced Review
James A. Counts, Benjamin M. Zeldes, Laura L. Lee, Christopher T. Straub, Michael W.W. Adams, Robert M. Kelly
Published Online: Feb 16 2017
DOI:10.1002/wsbm.1377

Abstract Full article on Wiley Online Library:   HTML | PDF
Understanding the mTOR signaling pathway via mathematical modeling

Advanced Review
Nurgazy Sulaimanov, Martin Klose, Hauke Busch, Melanie Boerries
Published Online: Feb 10 2017
DOI:10.1002/wsbm.1379

Abstract Full article on Wiley Online Library:   HTML | PDF
Regulatory elements in molecular networks

Advanced Review
Ashley S. Doane, Olivier Elemento
Published Online: Jan 17 2017
DOI:10.1002/wsbm.1374

Abstract Full article on Wiley Online Library:   HTML | PDF
Traditional and novel tools to probe the mitochondrial metabolism in health and disease

Advanced Review
Yanfei Zhang, José L. Avalos
Published Online: Jan 09 2017
DOI:10.1002/wsbm.1373

Abstract Full article on Wiley Online Library:   HTML | PDF
Cancer and inflammation

Overview
Lance L. Munn
Published Online: Dec 12 2016
DOI:10.1002/wsbm.1370

Abstract Full article on Wiley Online Library:   HTML | PDF
Modeling, signaling and cytoskeleton dynamics: integrated modeling‐experimental frameworks in cell migration

Advanced Review
Meng Sun, Muhammad H. Zaman
Published Online: Nov 15 2016
DOI:10.1002/wsbm.1365

Abstract Full article on Wiley Online Library:   HTML | PDF
Data sources for in vivo molecular profiling of human phenotypes

Advanced Review
Timothy Cardozo, Priyanka Gupta, Eric Ni, Lauren M. Young, Doreen Tivon, Klara Felsovalyi
Published Online: Sep 07 2016
DOI:10.1002/wsbm.1354

Abstract Full article on Wiley Online Library:   HTML | PDF
Omics‐based approaches to understand mechanosensitive endothelial biology and atherosclerosis

Advanced Review
Rachel D. Simmons, Sandeep Kumar, Salim Raid Thabet, Sanjoli Sur, Hanjoong Jo
Published Online: Jun 24 2016
DOI:10.1002/wsbm.1344

Abstract Full article on Wiley Online Library:   HTML | PDF
The reverse control of irreversible biological processes

Opinion
Kwang‐Hyun Cho, Jae Il Joo, Dongkwan Shin, Dongsan Kim, Sang‐Min Park
Published Online: Jun 21 2016
DOI:10.1002/wsbm.1346

Abstract Full article on Wiley Online Library:   HTML | PDF
CRISPR /Cas9 genome editing throws descriptive 3‐D genome folding studies for a loop

Advanced Review
Jonathan A. Beagan, Jennifer E. Phillips‐Cremins
Published Online: Jun 06 2016
DOI:10.1002/wsbm.1338

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems medicine in colorectal cancer: from a mathematical model toward a new type of clinical trial

Advanced Review
Nicoletta Castagnino, Massimo Maffei, Lorenzo Tortolina, Gabriele Zoppoli, Daniela Piras, Alessio Nencioni, Eva Moran, Alberto Ballestrero, Franco Patrone, Silvio Parodi
Published Online: May 30 2016
DOI:10.1002/wsbm.1342

Abstract Full article on Wiley Online Library:   HTML | PDF
Mitochondrial metabolic remodeling in response to genetic and environmental perturbations

Advanced Review
Kate E.R. Hollinshead, Daniel A. Tennant
Published Online: May 19 2016
DOI:10.1002/wsbm.1334

Abstract Full article on Wiley Online Library:   HTML | PDF
Adaptive resistance to antibiotics in bacteria: a systems biology perspective

Advanced Review
Santiago Sandoval‐Motta, Maximino Aldana
Published Online: Apr 21 2016
DOI:10.1002/wsbm.1335

Abstract Full article on Wiley Online Library:   HTML | PDF
Signaling via the NFκB system

Advanced Review
Simon Mitchell, Jesse Vargas, Alexander Hoffmann
Published Online: Mar 16 2016
DOI:10.1002/wsbm.1331

Abstract Full article on Wiley Online Library:   HTML | PDF
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In the Spotlight

Jens Nielsen

Jens Nielsen
is a Professor in the Department of Biology and Biological Engineering at Chalmers University of Technology in Göteborg, Sweden. His research focus is on systems biology of metabolism. The yeast Saccharomyces cerevisiae is the lab’s key organism for experimental research, but they also work with Aspergilli oryzae.

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