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WIREs Syst Biol Med
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Models of Systems Properties and Processes

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Integrating molecular networks with genetic variant interpretation for precision medicine

Overview
Emidio Capriotti, Kivilcim Ozturk, Hannah Carter
Published Online: Dec 12 2018
DOI:10.1002/wsbm.1443

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of robustness and homeostatic mechanisms

Overview
H. Frederik Nijhout, Janet A. Best, Michael C. Reed
Published Online: Oct 29 2018
DOI:10.1002/wsbm.1440

Abstract Full article on Wiley Online Library:   HTML | PDF
Mathematical modeling of circadian rhythms

Focus Article
Ameneh Asgari‐Targhi, Elizabeth B. Klerman
Published Online: Oct 17 2018
DOI:10.1002/wsbm.1439

Abstract Full article on Wiley Online Library:   HTML | PDF
Context‐dependent regulation of receptor tyrosine kinases: Insights from systems biology approaches

Focus Article
Inez Lam, Christina M. Pickering, Feilim Mac Gabhann
Published Online: Sep 26 2018
DOI:10.1002/wsbm.1437

Abstract Full article on Wiley Online Library:   HTML | PDF
The mammalian mycobiome: A complex system in a dynamic relationship with the host

Advanced Review
Ghee Chuan Lai, Tze Guan Tan, Norman Pavelka
Published Online: Sep 25 2018
DOI:10.1002/wsbm.1438

Abstract Full article on Wiley Online Library:   HTML | PDF
Computational methods for analyzing and modeling genome structure and organization

Focus Article
Dejun Lin, Giancarlo Bonora, Galip Gürkan Yardımcı, William S. Noble
Published Online: Jul 18 2018
DOI:10.1002/wsbm.1435

Abstract Full article on Wiley Online Library:   HTML | PDF
Quantitative systems models illuminate arrhythmia mechanisms in heart failure: Role of the Na+‐Ca2+‐Ca2+/calmodulin‐dependent protein kinase II‐reactive oxygen species feedback

Focus Article
Stefano Morotti, Eleonora Grandi
Published Online: Jul 17 2018
DOI:10.1002/wsbm.1434

Abstract Full article on Wiley Online Library:   HTML | PDF
Computational anatomy and diffeomorphometry: A dynamical systems model of neuroanatomy in the soft condensed matter continuum

Advanced Review
Michael I. Miller, Sylvain Arguillère, Daniel J. Tward, Laurent Younes
Published Online: Jun 04 2018
DOI:10.1002/wsbm.1425

Abstract Full article on Wiley Online Library:   HTML | PDF
Kinetic models of hematopoietic differentiation

Advanced Review
Victor Olariu, Carsten Peterson
Published Online: Apr 16 2018
DOI:10.1002/wsbm.1424

Abstract Full article on Wiley Online Library:   HTML | PDF
Multiscale systems biology of trauma‐induced coagulopathy

Focus Article
Evan Tsiklidis, Carrie Sims, Talid Sinno, Scott L. Diamond
Published Online: Feb 27 2018
DOI:10.1002/wsbm.1418

Abstract Full article on Wiley Online Library:   HTML | PDF
Genome‐scale metabolic models applied to human health and disease

Advanced Review
Daniel J Cook, Jens Nielsen
Published Online: Jun 23 2017
DOI:10.1002/wsbm.1393

Abstract Full article on Wiley Online Library:   HTML | PDF
Image‐based computational fluid dynamics in the lung: virtual reality or new clinical practice?

Advanced Review
Kelly S. Burrowes, Jan De Backer, Haribalan Kumar
Published Online: Jun 13 2017
DOI:10.1002/wsbm.1392

Abstract Full article on Wiley Online Library:   HTML | PDF
The best models of metabolism

Advanced Review
Eberhard O. Voit
Published Online: May 19 2017
DOI:10.1002/wsbm.1391

Abstract Full article on Wiley Online Library:   HTML | PDF
Biomechanics of the human uterus

Focus Article
Kristin M. Myers, David Elad
Published Online: May 12 2017
DOI:10.1002/wsbm.1388

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of cellular membranes: a convergence with biophysics

Advanced Review
Morgan Chabanon, Jeanne C. Stachowiak, Padmini Rangamani
Published Online: May 05 2017
DOI:10.1002/wsbm.1386

Abstract Full article on Wiley Online Library:   HTML | PDF
Trends in high‐throughput and functional neuroimaging in Caenorhabditis elegans

Focus Article
Yongmin Cho, Charles L. Zhao, Hang Lu
Published Online: Feb 21 2017
DOI:10.1002/wsbm.1376

Abstract Full article on Wiley Online Library:   HTML | PDF
Recent lab‐on‐chip developments for novel drug discovery

Opinion
Nauman Khalid, Isao Kobayashi, Mitsutoshi Nakajima
Published Online: Feb 17 2017
DOI:10.1002/wsbm.1381

Abstract Full article on Wiley Online Library:   HTML | PDF
Understanding the mTOR signaling pathway via mathematical modeling

Advanced Review
Nurgazy Sulaimanov, Martin Klose, Hauke Busch, Melanie Boerries
Published Online: Feb 10 2017
DOI:10.1002/wsbm.1379

Abstract Full article on Wiley Online Library:   HTML | PDF
Multiscale modeling methods in biomechanics

Advanced Review
Pinaki Bhattacharya, Marco Viceconti
Published Online: Jan 19 2017
DOI:10.1002/wsbm.1375

Abstract Full article on Wiley Online Library:   HTML | PDF
Insights into nuclear dynamics using live‐cell imaging approaches

Advanced Review
Rachel B. Bigley, Alexander Y. Payumo, Jeffrey M. Alexander, Guo N. Huang
Published Online: Jan 12 2017
DOI:10.1002/wsbm.1372

Abstract Full article on Wiley Online Library:   HTML | PDF
Toward modeling locomotion using electromyography‐informed 3D models: application to cerebral palsy

Focus Article
M. Sartori, J. W. Fernandez, L. Modenese, C. P. Carty, L. A. Barber, K. Oberhofer, J. Zhang, G. G. Handsfield, N. S. Stott, T. F. Besier, D. Farina, D. G. Lloyd
Published Online: Dec 21 2016
DOI:10.1002/wsbm.1368

Abstract Full article on Wiley Online Library:   HTML | PDF
Modeling, signaling and cytoskeleton dynamics: integrated modeling‐experimental frameworks in cell migration

Advanced Review
Meng Sun, Muhammad H. Zaman
Published Online: Nov 15 2016
DOI:10.1002/wsbm.1365

Abstract Full article on Wiley Online Library:   HTML | PDF
Mathematical modeling of the female reproductive system: from oocyte to delivery

Overview
Alys R Clark, Jennifer A Kruger
Published Online: Sep 09 2016
DOI:10.1002/wsbm.1353

Abstract Full article on Wiley Online Library:   HTML | PDF
In silico bone mechanobiology: modeling a multifaceted biological system

Advanced Review
Mario Giorgi, Stefaan W. Verbruggen, Damien Lacroix
Published Online: Sep 07 2016
DOI:10.1002/wsbm.1356

Abstract Full article on Wiley Online Library:   HTML | PDF
Modeling the second stage of labor

Focus Article
Xiani Yan, Jennifer A. Kruger, Xinshan Li, Poul M. F. Nielsen, Martyn P. Nash
Published Online: Aug 25 2016
DOI:10.1002/wsbm.1351

Abstract Full article on Wiley Online Library:   HTML | PDF
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