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WIREs Syst Biol Med
Impact Factor: 3.542

Translational, Genomic, and Systems Medicine

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Molecular networks in Network Medicine: Development and applications

Advanced Review
Jan Baumbach, Kimberly Glass, Gemma Vilahur, Davide Viggiano, Paolo Tieri, John Quackenbush, Manuela Petti, Paola Paci, Claudio Napoli, Cinzia Marchese, Joseph Loscalzo, Michele Gentili, Laurent Gatto, Giulia Fiscon, Lorenzo Farina, Antonella Di Costanzo, Federica Conte, Giovambattista Capasso, Giuditta Benincasa, Jean‐Luc Balligand, Lina Badimon, Marco Angelini, Lucia Altucci, Eleni Anastasiadou, Harald H. H. W. Schmidt, Edwin K. Silverman
Published Online: Apr 20 2020
DOI:10.1002/wsbm.1489

Abstract Full article on Wiley Online Library:   HTML | PDF
The immunologic Warburg effect: Evidence and therapeutic opportunities in autoimmunity

Advanced Review
Michael D. Kornberg
Published Online: Feb 27 2020
DOI:10.1002/wsbm.1486

Abstract Full article on Wiley Online Library:   HTML | PDF
Glucose transporter 1 in rheumatoid arthritis and autoimmunity

Advanced Review
Nadine Biesemann, Matthias Herrmann, Oezen Sercan‐Alp, Ekaterina Zezina
Published Online: Feb 21 2020
DOI:10.1002/wsbm.1483

Abstract Full article on Wiley Online Library:   HTML | PDF
How personalized heart modeling can help treatment of lethal arrhythmias: A focus on ventricular tachycardia ablation strategies in post‐infarction patients

Advanced Review
Natalia A. Trayanova, Ashish N. Doshi, Adityo Prakosa
Published Online: Jan 09 2020
DOI:10.1002/wsbm.1477

Abstract Full article on Wiley Online Library:   HTML | PDF
Structural neuroimaging of the altered brain stemming from pediatric and adolescent hearing loss—Scientific and clinical challenges

Advanced Review
J. Tilak Ratnanather
Published Online: Dec 04 2019
DOI:10.1002/wsbm.1469

Abstract Full article on Wiley Online Library:   HTML | PDF
MRI in systems medicine

Focus Article
Thomas T. Liu
Published Online: Jul 31 2019
DOI:10.1002/wsbm.1463

Abstract Full article on Wiley Online Library:   HTML | PDF
Hybrid modeling frameworks of tumor development and treatment

UPDATE
Ibrahim M. Chamseddine, Katarzyna A. Rejniak
Published Online: Jul 17 2019
DOI:10.1002/wsbm.1461

Abstract Full article on Wiley Online Library:   HTML | PDF
Agent‐based models of inflammation in translational systems biology: A decade later

UPDATE
Gary An, Yoram Vodovotz
Published Online: Jul 01 2019
DOI:10.1002/wsbm.1460

Abstract Full article on Wiley Online Library:   HTML | PDF
Integrating molecular networks with genetic variant interpretation for precision medicine

Overview
Emidio Capriotti, Kivilcim Ozturk, Hannah Carter
Published Online: Dec 12 2018
DOI:10.1002/wsbm.1443

Abstract Full article on Wiley Online Library:   HTML | PDF
Context‐dependent regulation of receptor tyrosine kinases: Insights from systems biology approaches

Focus Article
Inez Lam, Christina M. Pickering, Feilim Mac Gabhann
Published Online: Sep 26 2018
DOI:10.1002/wsbm.1437

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems approaches to optimizing deep brain stimulation therapies in Parkinson’s disease

Overview
Sabato Santaniello, John T. Gale, Sridevi V. Sarma
Published Online: Mar 20 2018
DOI:10.1002/wsbm.1421

Abstract Full article on Wiley Online Library:   HTML | PDF
PharmGKB: A worldwide resource for pharmacogenomic information

Advanced Review
Julia M. Barbarino, Michelle Whirl‐Carrillo, Russ B. Altman, Teri E. Klein
Published Online: Feb 23 2018
DOI:10.1002/wsbm.1417

Abstract Full article on Wiley Online Library:   HTML | PDF
Human microbiota, blood group antigens, and disease

Advanced Review
Susan C.J. Sumner, D. Rose Ewald
Published Online: Jan 09 2018
DOI:10.1002/wsbm.1413

Abstract Full article on Wiley Online Library:   HTML | PDF
Biomechanics of the human uterus

Focus Article
Kristin M. Myers, David Elad
Published Online: May 12 2017
DOI:10.1002/wsbm.1388

Abstract Full article on Wiley Online Library:   HTML | PDF
Integrated precision medicine: the role of electronic health records in delivering personalized treatment

Focus Article
Amy Sitapati, Hyeoneui Kim, Barbara Berkovich, Rebecca Marmor, Siddharth Singh, Robert El‐Kareh, Brian Clay, Lucila Ohno‐Machado
Published Online: Feb 16 2017
DOI:10.1002/wsbm.1378

Abstract Full article on Wiley Online Library:   HTML | PDF
Therapeutic genome engineering via CRISPR‐Cas systems

Advanced Review
Prashant Mali, Ana M. Moreno
Published Online: Feb 15 2017
DOI:10.1002/wsbm.1380

Abstract Full article on Wiley Online Library:   HTML | PDF
Modified mRNA as a therapeutic tool to induce cardiac regeneration in ischemic heart disease

Focus Article
Yoav Hadas, Michael G. Katz, Charles R. Bridges, Lior Zangi
Published Online: Dec 02 2016
DOI:10.1002/wsbm.1367

Abstract Full article on Wiley Online Library:   HTML | PDF
Computational approaches for the identification of cancer genes and pathways

Advanced Review
Christos M. Dimitrakopoulos, Niko Beerenwinkel
Published Online: Nov 11 2016
DOI:10.1002/wsbm.1364

Abstract Full article on Wiley Online Library:   HTML | PDF
Blood type biochemistry and human disease

Focus Article
D. Rose Ewald, Susan C.J. Sumner
Published Online: Sep 07 2016
DOI:10.1002/wsbm.1355

Abstract Full article on Wiley Online Library:   HTML | PDF
Omics‐based approaches to understand mechanosensitive endothelial biology and atherosclerosis

Advanced Review
Rachel D. Simmons, Sandeep Kumar, Salim Raid Thabet, Sanjoli Sur, Hanjoong Jo
Published Online: Jun 24 2016
DOI:10.1002/wsbm.1344

Abstract Full article on Wiley Online Library:   HTML | PDF
Engineering of synthetic gene circuits for (re‐)balancing physiological processes in chronic diseases

Advanced Review
Lina Schukur, Martin Fussenegger
Published Online: Jun 24 2016
DOI:10.1002/wsbm.1345

Abstract Full article on Wiley Online Library:   HTML | PDF
Mathematical models of breast and ovarian cancers

Advanced Review
Dana‐Adriana Botesteanu, Stanley Lipkowitz, Jung‐Min Lee, Doron Levy
Published Online: Jun 03 2016
DOI:10.1002/wsbm.1343

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems medicine in colorectal cancer: from a mathematical model toward a new type of clinical trial

Advanced Review
Nicoletta Castagnino, Massimo Maffei, Lorenzo Tortolina, Gabriele Zoppoli, Daniela Piras, Alessio Nencioni, Eva Moran, Alberto Ballestrero, Franco Patrone, Silvio Parodi
Published Online: May 30 2016
DOI:10.1002/wsbm.1342

Abstract Full article on Wiley Online Library:   HTML | PDF
In silico methods for drug repurposing and pharmacology

Overview
Rachel A. Hodos, Brian A. Kidd, Khader Shameer, Ben P. Readhead, Joel T. Dudley
Published Online: Apr 15 2016
DOI:10.1002/wsbm.1337

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology approaches for identifying adverse drug reactions and elucidating their underlying biological mechanisms

Advanced Review
Mary Regina Boland, Alexandra Jacunski, Tal Lorberbaum, Joseph D. Romano, Robert Moskovitch, Nicholas P. Tatonetti
Published Online: Nov 12 2015
DOI:10.1002/wsbm.1323

Abstract Full article on Wiley Online Library:   HTML | PDF
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