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WIREs Syst Biol Med
Impact Factor: 3.542

Translational, Genomic, and Systems Medicine

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Systems medicine: evolution of systems biology from bench to bedside

Overview
Rui‐Sheng Wang, Bradley A. Maron, Joseph Loscalzo
Published Online: Apr 17 2015
DOI:10.1002/wsbm.1297

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems engineering meets quantitative systems pharmacology: from low‐level targets to engaging the host defenses

Opinion
Ioannis P. Androulakis
Published Online: Mar 16 2015
DOI:10.1002/wsbm.1294

Abstract Full article on Wiley Online Library:   HTML | PDF
A practical model for economic evaluation of tissue‐engineered therapies

Focus Article
Tien‐En Tan, Gary S. L. Peh, Eric A. Finkelstein, Jodhbir S. Mehta
Published Online: Feb 17 2015
DOI:10.1002/wsbm.1292

Abstract Full article on Wiley Online Library:   HTML | PDF
Exploring hypertension genome‐wide association studies findings and impact on pathophysiology, pathways, and pharmacogenetics

Advanced Review
Claudia P Cabrera, Fu Liang Ng, Helen R Warren, Michael R Barnes, Patricia B Munroe, Mark J Caulfield
Published Online: Feb 06 2015
DOI:10.1002/wsbm.1290

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of polycystic kidney disease: a critical review

Focus Article
Luis Fernando Menezes, Gregory G. Germino
Published Online: Feb 02 2015
DOI:10.1002/wsbm.1289

Abstract Full article on Wiley Online Library:   HTML | PDF
Personalizing oncology treatments by predicting drug efficacy, side‐effects, and improved therapy: mathematics, statistics, and their integration

Advanced Review
Zvia Agur, Moran Elishmereni, Yuri Kheifetz
Published Online: Mar 06 2014
DOI:10.1002/wsbm.1263

Abstract Full article on Wiley Online Library:   HTML | PDF
Recent advances in computational methodology for simulation of mechanical circulatory assist devices

Advanced Review
Alison L. Marsden, Yuri Bazilevs, Christopher C. Long, Marek Behr
Published Online: Jan 21 2014
DOI:10.1002/wsbm.1260

Abstract Full article on Wiley Online Library:   HTML | PDF
Using systems approaches to address challenges for clinical implementation of pharmacogenomics

Advanced Review
Jason H. Karnes, Sara Van Driest, Erica A. Bowton, Peter E. Weeke, Jonathan D. Mosley, Josh F. Peterson, Joshua C. Denny, Dan M. Roden
Published Online: Dec 06 2013
DOI:10.1002/wsbm.1255

Abstract Full article on Wiley Online Library:   HTML | PDF
Genome network medicine: innovation to overcome huge challenges in cancer therapy

Focus Article
Dimitrios H. Roukos
Published Online: Dec 06 2013
DOI:10.1002/wsbm.1254

Abstract Full article on Wiley Online Library:   HTML | PDF
Advances in modeling ventricular arrhythmias: from mechanisms to the clinic

Focus Article
Natalia A. Trayanova, Patrick M. Boyle
Published Online: Dec 06 2013
DOI:10.1002/wsbm.1256

Abstract Full article on Wiley Online Library:   HTML | PDF
Using systems biology approaches to understand cardiac inflammation and extracellular matrix remodeling in the setting of myocardial infarction

Advanced Review
Omid Ghasemi, Yonggang Ma, Merry L. Lindsey, Yu‐Fang Jin
Published Online: Nov 08 2013
DOI:10.1002/wsbm.1248

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology‐embedded target validation: improving efficacy in drug discovery

Opinion
Walter Kolch, Boris N. Kholodenko, William Fitzmaurice, Benedikt A. Minke, Drieke Vandamme
Published Online: Nov 08 2013
DOI:10.1002/wsbm.1253

Abstract Full article on Wiley Online Library:   HTML | PDF
Vascular tissue engineering: from in vitro to in situ

Advanced Review
Song Li, Debanti Sengupta, Shu Chien
Published Online: Oct 22 2013
DOI:10.1002/wsbm.1246

Abstract Full article on Wiley Online Library:   HTML | PDF
Agent‐based modeling: a systematic assessment of use cases and requirements for enhancing pharmaceutical research and development productivity

Advanced Review
C. Anthony Hunt, Ryan C. Kennedy, Sean H. J. Kim, Glen E. P. Ropella
Published Online: Jun 04 2013
DOI:10.1002/wsbm.1222

Abstract Full article on Wiley Online Library:   HTML | PDF
Mathematical modeling of folate metabolism

Focus Article
John C. Panetta, Steven W. Paugh, William E. Evans
Published Online: May 22 2013
DOI:10.1002/wsbm.1227

Abstract Full article on Wiley Online Library:   HTML | PDF
Branched‐chain amino acid supplementation: impact on signaling and relevance to critical illness

Advanced Review
John S. A. Mattick, Kubra Kamisoglu, Marianthi G. Ierapetritou, Ioannis P. Androulakis, Francois Berthiaume
Published Online: Mar 29 2013
DOI:10.1002/wsbm.1219

Abstract Full article on Wiley Online Library:   HTML | PDF
Toward the virtual stomach: progress in multiscale modeling of gastric electrophysiology and motility

Focus Article
Peng Du, Gregory O'Grady, Jerry Gao, Shameer Sathar, Leo K. Cheng
Published Online: Mar 05 2013
DOI:10.1002/wsbm.1218

Abstract Full article on Wiley Online Library:   HTML | PDF
Lower urinary tract development and disease

Advanced Review
Hila Milo Rasouly, Weining Lu
Published Online: Feb 13 2013
DOI:10.1002/wsbm.1212

Abstract Full article on Wiley Online Library:   HTML | PDF
Developing melanoma therapeutics: overview and update

Overview
John B. Korman, David E. Fisher
Published Online: Feb 13 2013
DOI:10.1002/wsbm.1210

Abstract Full article on Wiley Online Library:   HTML | PDF
Genomics and epigenomics of colorectal cancer

Advanced Review
Michal‐Ruth Schweiger, Michelle Hussong, Christina Röhr, Hans Lehrach
Published Online: Jan 16 2013
DOI:10.1002/wsbm.1206

Abstract Full article on Wiley Online Library:   HTML | PDF
Can a systems biology approach unlock the mysteries of Kawasaki disease?

Focus Article
Anne H. Rowley
Published Online: Jan 04 2013
DOI:10.1002/wsbm.1202

Abstract Full article on Wiley Online Library:   HTML | PDF
Pharmacogenomics discovery and implementation in genome‐wide association studies era

Opinion
Xiuqin Ni, Wei Zhang, R. Stephanie Huang
Published Online: Nov 27 2012
DOI:10.1002/wsbm.1199

Abstract Full article on Wiley Online Library:   HTML | PDF
Promise of personalized omics to precision medicine

Advanced Review
Rui Chen, Michael Snyder
Published Online: Nov 26 2012
DOI:10.1002/wsbm.1198

Abstract Full article on Wiley Online Library:   HTML | PDF
Mechanisms of memory enhancement

Advanced Review
Sarah A. Stern, Cristina M. Alberini
Published Online: Nov 13 2012
DOI:10.1002/wsbm.1196

Abstract Full article on Wiley Online Library:   HTML | PDF
Stem cell bioengineering at the interface of systems‐based models and high‐throughput platforms

Overview
Gregory H. Underhill
Published Online: Aug 23 2012
DOI:10.1002/wsbm.1189

Abstract Full article on Wiley Online Library:   HTML | PDF
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