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WIREs Syst Biol Med
Impact Factor: 3.542

Translational, Genomic, and Systems Medicine

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From base pair to bedside: molecular simulation and the translation of genomics to personalized medicine

Advanced Review
David W. Wright, Shunzhou Wan, Nour Shublaq, Stefan J. Zasada, Peter V. Coveney
Published Online: Aug 15 2012
DOI:10.1002/wsbm.1186

Abstract Full article on Wiley Online Library:   HTML | PDF
The role of regulatory T cells in neurodegenerative diseases

Advanced Review
Feng He, Rudi Balling
Published Online: Aug 15 2012
DOI:10.1002/wsbm.1187

Abstract Full article on Wiley Online Library:   HTML | PDF
Recent approaches to the prioritization of candidate disease genes

Advanced Review
Nadezhda T. Doncheva, Tim Kacprowski, Mario Albrecht
Published Online: Jun 11 2012
DOI:10.1002/wsbm.1177

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems pharmacology, pharmacogenetics, and clinical trial design in network medicine

Advanced Review
Joseph Loscalzo, Scott Weiss, Elliott Antman
Published Online: May 11 2012
DOI:10.1002/wsbm.1173

Abstract Full article on Wiley Online Library:   HTML | PDF
Deciphering the complexities of human diseases and disorders by coupling induced‐pluripotent stem cells and systems genetics

Advanced Review
Wing Y. Chang, Kamal Garcha, Janet L. Manias, William L. Stanford
Published Online: Apr 10 2012
DOI:10.1002/wsbm.1170

Abstract Full article on Wiley Online Library:   HTML | PDF
Integration of proteomics into systems biology of cancer

Advanced Review
S. Hanash, M. Schliekelman, Q. Zhang, A. Taguchi
Published Online: Mar 08 2012
DOI:10.1002/wsbm.1169

Abstract Full article on Wiley Online Library:   HTML | PDF
The virtual liver: a multidisciplinary, multilevel challenge for systems biology

Overview
Hermann‐Georg Holzhütter, Dirk Drasdo, Tobias Preusser, Jörg Lippert, Adriano M. Henney
Published Online: Jan 13 2012
DOI:10.1002/wsbm.1158

Abstract Full article on Wiley Online Library:   HTML | PDF
Engineered tissue grafts: opportunities and challenges in regenerative medicine

Focus Article
Adam W. Feinberg
Published Online: Oct 19 2011
DOI:10.1002/wsbm.164

Abstract Full article on Wiley Online Library:   HTML | PDF
A systems biology approach to synovial joint lubrication in health, injury, and disease

Overview
Alexander Y. Hui, William J. McCarty, Koichi Masuda, Gary S. Firestein, Robert L. Sah
Published Online: Aug 08 2011
DOI:10.1002/wsbm.157

Abstract Full article on Wiley Online Library:   HTML | PDF
Pathways, networks, and systems medicine—the meeting place of the Aegean and the mind

Editorial Commentary
Shankar Subramaniam, Joseph H. Nadeau
Published Online: Apr 01 2011
DOI:10.1002/wsbm.153

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology and the future of medicine

Opinion
Joseph Loscalzo, Albert‐Laszlo Barabasi
Published Online: Feb 24 2011
DOI:10.1002/wsbm.144

Abstract Full article on Wiley Online Library:   HTML | PDF
Estrogen receptor‐positive breast cancer: a multidisciplinary challenge

Focus Article
Wilbert Zwart, Vasiliki Theodorou, Jason S. Carroll
Published Online: Feb 08 2011
DOI:10.1002/wsbm.109

Abstract Full article on Wiley Online Library:   HTML | PDF
Role of systems pharmacology in understanding drug adverse events

Opinion
Seth I. Berger, Ravi Iyengar
Published Online: Aug 27 2010
DOI:10.1002/wsbm.114

Abstract Full article on Wiley Online Library:   HTML | PDF
Emerging clinical applications in cardiovascular pharmacogenomics

Advanced Review
Samir B. Damani, Eric J. Topol
Published Online: Aug 20 2010
DOI:10.1002/wsbm.113

Abstract Full article on Wiley Online Library:   HTML | PDF
Modeling of blood flow in arterial trees

Focus Article
Tomer Anor, Leopold Grinberg, Hyoungsu Baek, Joseph R. Madsen, Mahesh V. Jayaraman, George E. Karniadakis
Published Online: Aug 04 2010
DOI:10.1002/wsbm.90

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems medicine—viewed through the real and computing lenses

Editorial Commentary
Shankar Subramaniam, Joseph H. Nadeau
Published Online: Jun 15 2010
DOI:10.1002/wsbm.103

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems Biology and Medicine—Metazoan Life and Processes

Editorial Commentary
Shankar Subramaniam, Joseph H. Nadeau
Published Online: Apr 09 2010
DOI:10.1002/wsbm.99

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of pro‐angiogenic therapies targeting the VEGF system

Focus Article
Feilim Mac Gabhann, Amina A. Qutub, Brian H. Annex, Aleksander S. Popel
Published Online: Apr 07 2010
DOI:10.1002/wsbm.92

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems analysis of salivary gland development and disease

Advanced Review
Melinda Larsen, Kenneth M. Yamada, Kurt Musselmann
Published Online: Apr 01 2010
DOI:10.1002/wsbm.94

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems approaches and algorithms for discovery of combinatorial therapies

Advanced Review
Jacob D. Feala, Jorge Cortes, Phillip M. Duxbury, Carlo Piermarocchi, Andrew D. McCulloch, Giovanni Paternostro
Published Online: Mar 26 2010
DOI:10.1002/wsbm.51

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems Biology and Medicine—Meta‐Issues and Frameworks

Editorial Commentary
Shankar Subramaniam, Joseph H. Nadeau
Published Online: Mar 26 2010
DOI:10.1002/wsbm.98

Abstract Full article on Wiley Online Library:   HTML | PDF
The network as the target

Opinion
Julie E. Baggs, Michael E. Hughes, John B. Hogenesch
Published Online: Mar 26 2010
DOI:10.1002/wsbm.57

Abstract Full article on Wiley Online Library:   HTML | PDF
Toward a VPH/Physiome ToolKit

Overview
Alan Garny, Jonathan Cooper, Peter J. Hunter
Published Online: Mar 26 2010
DOI:10.1002/wsbm.63

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology—old wine in a new bottle or is the bottle changing the wine?

Editorial Commentary
Joseph H. Nadeau, Shankar Subramaniam
Published Online: Jan 15 2010
DOI:10.1002/wsbm.91

Abstract Full article on Wiley Online Library:   HTML | PDF
Pharmacogenomics: a systems approach

Overview
Liewei Wang
Published Online: Jan 15 2010
DOI:10.1002/wsbm.42

Abstract Full article on Wiley Online Library:   HTML | PDF
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