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WIREs Syst Biol Med
Impact Factor: 2.941

Developmental Processes in Health and Disease

Listings: 1-10   11-20   21-23
Riding the crest of the wave: parallels between the neural crest and cancer in epithelial‐to‐mesenchymal transition and migration

Focus Article
Davalyn R. Powell, Alex J. Blasky, Steven G. Britt, Kristin B. Artinger
Published Online: Apr 10 2013
DOI:10.1002/wsbm.1224

Abstract Full article on Wiley Online Library:   HTML | PDF
Hierarchical approaches for systems modeling in cardiac development

Overview
Russell A. Gould, Lina M. Aboulmouna, Jeffrey D. Varner, Jonathan T. Butcher
Published Online: Mar 05 2013
DOI:10.1002/wsbm.1217

Abstract Full article on Wiley Online Library:   HTML | PDF
Lower urinary tract development and disease

Advanced Review
Hila Milo Rasouly, Weining Lu
Published Online: Feb 13 2013
DOI:10.1002/wsbm.1212

Abstract Full article on Wiley Online Library:   HTML | PDF
Recent advances in prostate development and links to prostatic diseases

Focus Article
Ginny L. Powers, Paul C. Marker
Published Online: Jan 17 2013
DOI:10.1002/wsbm.1208

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of lung development and regeneration: current knowledge and recommendations for future research

Opinion
James S. Hagood, Namasivayam Ambalavanan
Published Online: Jan 04 2013
DOI:10.1002/wsbm.1205

Abstract Full article on Wiley Online Library:   HTML | PDF
Toward a systems‐level understanding of the Hedgehog signaling pathway: defining the complex, robust, and fragile

Focus Article
Pamela V. Tran, Salil A. Lachke, Rolf W. Stottmann
Published Online: Oct 11 2012
DOI:10.1002/wsbm.1193

Abstract Full article on Wiley Online Library:   HTML | PDF
Gut stem cells in tissue renewal and disease: methods, markers, and myths

Focus Article
Pamela Rizk, Nick Barker
Published Online: May 29 2012
DOI:10.1002/wsbm.1176

Abstract Full article on Wiley Online Library:   HTML | PDF
Diverse functional networks of Tbx3 in development and disease

Focus Article
Andrew J. Washkowitz, Svetlana Gavrilov, Salma Begum, Virginia E. Papaioannou
Published Online: Feb 14 2012
DOI:10.1002/wsbm.1162

Abstract Full article on Wiley Online Library:   HTML | PDF
Multiscale models of thrombogenesis

Advanced Review
Zhiliang Xu, Oleg Kim, Malgorzata Kamocka, Elliot D. Rosen, Mark Alber
Published Online: Jan 13 2012
DOI:10.1002/wsbm.1160

Abstract Full article on Wiley Online Library:   HTML | PDF
Mechanisms controlling hematopoietic stem cell functions during normal hematopoiesis and hematological malignancies

Advanced Review
Matthew R. Warr, Eric M. Pietras, Emmanuelle Passegué
Published Online: Mar 15 2011
DOI:10.1002/wsbm.145

Abstract Full article on Wiley Online Library:   HTML | PDF

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In the Spotlight

Philip Benfey

Philip Benfey

Is intrigued by one of the key questions in developmental biology: how cells acquire their identities. This is an important question in human development, where stem cells divide and differentiate into skin, muscle, fat etc. It is equally central to plant development, where most organs and cells are formed from stem cell populations known as meristems. The Benfey lab addresses this question using a combination of genetics, molecular biology, and genomics to identify and characterize the genes that regulate formation of the root in the plant model system, Arabidopsis thaliana. The choice of the root as a model was based on the simplicity of its organization and its stereotyped developmental program.

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