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Developmental Processes in Health and Disease

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Going low to reach high: Small‐scale ChIP‐seq maps new terrain

Advanced Review
John Arne Dahl, Gregor D. Gilfillan, Klaus Hansen, Mads Lerdrup, Adeel Manaf, Madeleine Fosslie
Published Online: Sep 03 2019
DOI:10.1002/wsbm.1465

Abstract Full article on Wiley Online Library:   HTML | PDF
Skeletal muscle: A review of molecular structure and function, in health and disease

Advanced Review
Shankar Subramaniam, Kavitha Mukund
Published Online: Aug 13 2019
DOI:10.1002/wsbm.1462

Abstract Full article on Wiley Online Library:   HTML | PDF
Decoding pluripotency: Genetic screens to interrogate the acquisition, maintenance, and exit of pluripotency

Overview
Qing V. Li, Bess P. Rosen, Danwei Huangfu
Published Online: Aug 13 2019
DOI:10.1002/wsbm.1464

Abstract Full article on Wiley Online Library:   HTML | PDF
Chromatin modifications in metabolic disease: Potential mediators of long‐term disease risk

Focus Article
Dustin E. Schones, Kevin R. Costello
Published Online: Jan 25 2018
DOI:10.1002/wsbm.1416

Abstract Full article on Wiley Online Library:   HTML | PDF
Quantitative approaches for investigating the spatial context of gene expression

Focus Article
Je H. Lee
Published Online: Dec 21 2016
DOI:10.1002/wsbm.1369

Abstract Full article on Wiley Online Library:   HTML | PDF
Behavioral epigenetics

Primer
David S. Moore
Published Online: Dec 01 2016
DOI:10.1002/wsbm.1333

Abstract Full article on Wiley Online Library:   HTML | PDF
Mathematical modeling of the female reproductive system: from oocyte to delivery

Overview
Alys R Clark, Jennifer A Kruger
Published Online: Sep 09 2016
DOI:10.1002/wsbm.1353

Abstract Full article on Wiley Online Library:   HTML | PDF
Multiscale modeling of brain dynamics: from single neurons and networks to mathematical tools

Advanced Review
Constantinos Siettos, Jens Starke
Published Online: Jun 24 2016
DOI:10.1002/wsbm.1348

Abstract Full article on Wiley Online Library:   HTML | PDF
CRISPR/Cas9 genome editing throws descriptive 3‐D genome folding studies for a loop

Advanced Review
Jonathan A. Beagan, Jennifer E. Phillips‐Cremins
Published Online: Jun 06 2016
DOI:10.1002/wsbm.1338

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems analysis of host–parasite interactions

Advanced Review
Justine Swann, Neema Jamshidi, Nathan E. Lewis, Elizabeth A. Winzeler
Published Online: Aug 26 2015
DOI:10.1002/wsbm.1311

Abstract Full article on Wiley Online Library:   HTML | PDF
Genome‐wide association studies in biliary atresia

Advanced Review
Mylarappa Ningappa, Jun Min, Brandon W. Higgs, Chethan Ashokkumar, Sarangarajan Ranganathan, Rakesh Sindhi
Published Online: May 11 2015
DOI:10.1002/wsbm.1303

Abstract Full article on Wiley Online Library:   HTML | PDF
The role of the microbiota in ageing: current state and perspectives

Focus Article
Denise B. Lynch, Ian B. Jeffery, Paul W. O'Toole
Published Online: Mar 16 2015
DOI:10.1002/wsbm.1293

Abstract Full article on Wiley Online Library:   HTML | PDF
Experience‐sensitive epigenetic mechanisms, developmental plasticity, and the biological embedding of chronic disease risk

Overview
Vincent T. Cunliffe
Published Online: Feb 20 2015
DOI:10.1002/wsbm.1291

Abstract Full article on Wiley Online Library:   HTML | PDF
Signaling networks in palate development

Focus Article
Jamie Lane, Vesa Kaartinen
Published Online: Mar 18 2014
DOI:10.1002/wsbm.1265

Abstract Full article on Wiley Online Library:   HTML | PDF
Axes of differentiation in breast cancer: untangling stemness, lineage identity, and the epithelial to mesenchymal transition

Advanced Review
Roy Z. Granit, Michal Slyper, Ittai Ben‐Porath
Published Online: Nov 08 2013
DOI:10.1002/wsbm.1252

Abstract Full article on Wiley Online Library:   HTML | PDF
Reprogramming cells and tissue patterning via bioelectrical pathways: molecular mechanisms and biomedical opportunities

Opinion
Michael Levin
Published Online: Jul 29 2013
DOI:10.1002/wsbm.1236

Abstract Full article on Wiley Online Library:   HTML | PDF
Using a systems biology approach to understand and study the mechanisms of metastasis

Focus Article
Ngoc‐Han Ha, Kent W. Hunter
Published Online: Jul 19 2013
DOI:10.1002/wsbm.1237

Abstract Full article on Wiley Online Library:   HTML | PDF
Endothelial cell motility, coordination and pattern formation during vasculogenesis

Advanced Review
Andras Czirok
Published Online: Jul 15 2013
DOI:10.1002/wsbm.1233

Abstract Full article on Wiley Online Library:   HTML | PDF
Riding the crest of the wave: parallels between the neural crest and cancer in epithelial‐to‐mesenchymal transition and migration

Focus Article
Davalyn R. Powell, Alex J. Blasky, Steven G. Britt, Kristin B. Artinger
Published Online: Apr 10 2013
DOI:10.1002/wsbm.1224

Abstract Full article on Wiley Online Library:   HTML | PDF
Hierarchical approaches for systems modeling in cardiac development

Overview
Russell A. Gould, Lina M. Aboulmouna, Jeffrey D. Varner, Jonathan T. Butcher
Published Online: Mar 05 2013
DOI:10.1002/wsbm.1217

Abstract Full article on Wiley Online Library:   HTML | PDF
Lower urinary tract development and disease

Advanced Review
Hila Milo Rasouly, Weining Lu
Published Online: Feb 13 2013
DOI:10.1002/wsbm.1212

Abstract Full article on Wiley Online Library:   HTML | PDF
Recent advances in prostate development and links to prostatic diseases

Focus Article
Ginny L. Powers, Paul C. Marker
Published Online: Jan 17 2013
DOI:10.1002/wsbm.1208

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of lung development and regeneration: current knowledge and recommendations for future research

Opinion
James S. Hagood, Namasivayam Ambalavanan
Published Online: Jan 04 2013
DOI:10.1002/wsbm.1205

Abstract Full article on Wiley Online Library:   HTML | PDF
Toward a systems‐level understanding of the Hedgehog signaling pathway: defining the complex, robust, and fragile

Focus Article
Pamela V. Tran, Salil A. Lachke, Rolf W. Stottmann
Published Online: Oct 11 2012
DOI:10.1002/wsbm.1193

Abstract Full article on Wiley Online Library:   HTML | PDF
Gut stem cells in tissue renewal and disease: methods, markers, and myths

Focus Article
Pamela Rizk, Nick Barker
Published Online: May 29 2012
DOI:10.1002/wsbm.1176

Abstract Full article on Wiley Online Library:   HTML | PDF
Diverse functional networks of Tbx3 in development and disease

Focus Article
Andrew J. Washkowitz, Svetlana Gavrilov, Salma Begum, Virginia E. Papaioannou
Published Online: Feb 14 2012
DOI:10.1002/wsbm.1162

Abstract Full article on Wiley Online Library:   HTML | PDF
Multiscale models of thrombogenesis

Advanced Review
Zhiliang Xu, Oleg Kim, Malgorzata Kamocka, Elliot D. Rosen, Mark Alber
Published Online: Jan 13 2012
DOI:10.1002/wsbm.1160

Abstract Full article on Wiley Online Library:   HTML | PDF
Mechanisms controlling hematopoietic stem cell functions during normal hematopoiesis and hematological malignancies

Advanced Review
Matthew R. Warr, Eric M. Pietras, Emmanuelle Passegué
Published Online: Mar 15 2011
DOI:10.1002/wsbm.145

Abstract Full article on Wiley Online Library:   HTML | PDF
Modeling the control of planar cell polarity

Advanced Review
Jeffrey D. Axelrod, Claire J. Tomlin
Published Online: Feb 16 2011
DOI:10.1002/wsbm.138

Abstract Full article on Wiley Online Library:   HTML | PDF
MicroRNAs in cardiomyocyte development

Advanced Review
Andrea P. Malizia, Da‐Zhi Wang
Published Online: Feb 08 2011
DOI:10.1002/wsbm.111

Abstract Full article on Wiley Online Library:   HTML | PDF
Signaling pathways in early cardiac development

Advanced Review
Wenrui Liu, Ann C. Foley
Published Online: Feb 08 2011
DOI:10.1002/wsbm.112

Abstract Full article on Wiley Online Library:   HTML | PDF
Cardiac function and disease: emerging role of small ubiquitin‐related modifier

Advanced Review
Jun Wang
Published Online: Dec 31 2010
DOI:10.1002/wsbm.130

Abstract Full article on Wiley Online Library:   HTML | PDF
The critical protein interactions and structures that elicit growth deregulation in cancer and viral replication

Focus Article
Clodagh C. O'Shea, Andrew P. May, Horng D. Ou
Published Online: Dec 16 2010
DOI:10.1002/wsbm.88

Abstract Full article on Wiley Online Library:   HTML | PDF
Gene–environment interactions, folate metabolism and the embryonic nervous system

Focus Article
M. Elizabeth Ross
Published Online: Jun 15 2010
DOI:10.1002/wsbm.72

Abstract Full article on Wiley Online Library:   HTML | PDF
Branch formation during organ development

Focus Article
Nikolce Gjorevski, Celeste M. Nelson
Published Online: Apr 21 2010
DOI:10.1002/wsbm.96

Abstract Full article on Wiley Online Library:   HTML | PDF
Building the developmental oculome: systems biology in vertebrate eye development and disease

Advanced Review
Salil A. Lachke, Richard L. Maas
Published Online: Apr 09 2010
DOI:10.1002/wsbm.59

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems analysis of salivary gland development and disease

Advanced Review
Melinda Larsen, Kenneth M. Yamada, Kurt Musselmann
Published Online: Apr 01 2010
DOI:10.1002/wsbm.94

Abstract Full article on Wiley Online Library:   HTML | PDF
Cardiac lineage selection: integrating biological complexity into computational models

Advanced Review
Ann Foley
Published Online: Nov 13 2009
DOI:10.1002/wsbm.43

Abstract Full article on Wiley Online Library:   HTML | PDF
Vertebrate retina and hypothalamus development

Focus Article
Mardi S. Byerly, Seth Blackshaw
Published Online: Nov 13 2009
DOI:10.1002/wsbm.22

Abstract Full article on Wiley Online Library:   HTML | PDF
Regulation of endothelial cell functions by basement membrane‐ and arachidonic acid‐derived products

Focus Article
Ambra Pozzi, Roy Zent
Published Online: Sep 22 2009
DOI:10.1002/wsbm.7

Abstract Full article on Wiley Online Library:   HTML | PDF
A systems biology approach to defining metastatic biomarkers and signaling pathways

Focus Article
Natalie E. Goldberger, Kent W. Hunter
Published Online: May 05 2009
DOI:10.1002/wsbm.6

Abstract Full article on Wiley Online Library:   HTML | PDF
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