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WIREs Syst Biol Med
Impact Factor: 2.941

Mammalian Physiology in Health and Disease

Listings: 1-10   11-20   21-30
Cyclic nucleotide signaling in intestinal epithelia: getting to the gut of the matter

Overview
Najla Arshad, Sandhya S. Visweswariah
Published Online: Apr 22 2013
DOI:10.1002/wsbm.1223

Abstract Full article on Wiley Online Library:   HTML | PDF
Branched‐chain amino acid supplementation: impact on signaling and relevance to critical illness

Advanced Review
John S. A. Mattick, Kubra Kamisoglu, Marianthi G. Ierapetritou, Ioannis P. Androulakis, Francois Berthiaume
Published Online: Mar 29 2013
DOI:10.1002/wsbm.1219

Abstract Full article on Wiley Online Library:   HTML | PDF
Modeling cellular compartmentation in one‐carbon metabolism

Advanced Review
Marco Scotti, Lorenzo Stella, Emily J. Shearer, Patrick J. Stover
Published Online: Feb 13 2013
DOI:10.1002/wsbm.1209

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of adipose tissue metabolism: regulation of growth, signaling and inflammation

Advanced Review
Sara Manteiga, Kyungoh Choi, Arul Jayaraman, Kyongbum Lee
Published Online: Feb 13 2013
DOI:10.1002/wsbm.1213

Abstract Full article on Wiley Online Library:   HTML | PDF
Can a systems biology approach unlock the mysteries of Kawasaki disease?

Focus Article
Anne H. Rowley
Published Online: Jan 04 2013
DOI:10.1002/wsbm.1202

Abstract Full article on Wiley Online Library:   HTML | PDF
Lymphatic vessels in health and disease

Focus Article
Cristina T. Kesler, Shan Liao, Lance L. Munn, Timothy P. Padera
Published Online: Dec 03 2012
DOI:10.1002/wsbm.1201

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems analysis of biological networks in skeletal muscle function

Advanced Review
Lucas R. Smith, Gretchen Meyer, Richard L. Lieber
Published Online: Nov 27 2012
DOI:10.1002/wsbm.1197

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology approaches to finding novel pain mediators

Advanced Review
Ana Antunes‐Martins, James R. Perkins, Jonathan Lees, Tobias Hildebrandt, Christine Orengo, David L.H. Bennett
Published Online: Oct 11 2012
DOI:10.1002/wsbm.1192

Abstract Full article on Wiley Online Library:   HTML | PDF
Role of fibroblast growth factor signaling in vascular formation and maintenance: orchestrating signaling networks as an integrated system

Focus Article
Masahiro Murakami, Takashi Sakurai
Published Online: Aug 28 2012
DOI:10.1002/wsbm.1190

Abstract Full article on Wiley Online Library:   HTML | PDF
Large‐scale mouse knockouts and phenotypes

Advanced Review
Ramiro Ramírez‐Solis, Edward Ryder, Richard Houghton, Jacqueline K. White, Joanna Bottomley
Published Online: Aug 15 2012
DOI:10.1002/wsbm.1183

Abstract Full article on Wiley Online Library:   HTML | PDF

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Philip Benfey

Philip Benfey

Is intrigued by one of the key questions in developmental biology: how cells acquire their identities. This is an important question in human development, where stem cells divide and differentiate into skin, muscle, fat etc. It is equally central to plant development, where most organs and cells are formed from stem cell populations known as meristems. The Benfey lab addresses this question using a combination of genetics, molecular biology, and genomics to identify and characterize the genes that regulate formation of the root in the plant model system, Arabidopsis thaliana. The choice of the root as a model was based on the simplicity of its organization and its stereotyped developmental program.

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