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WIREs Syst Biol Med
Impact Factor: 2.941

Organismal Models

Large‐scale mouse knockouts and phenotypes

Advanced Review
Ramiro Ramírez‐Solis, Edward Ryder, Richard Houghton, Jacqueline K. White, Joanna Bottomley
Published Online: Aug 15 2012
DOI:10.1002/wsbm.1183

Abstract Full article on Wiley Online Library:   HTML | PDF
Computational models for the study of heart–lung interactions in mammals

Advanced Review
Alona Ben‐Tal
Published Online: Dec 02 2011
DOI:10.1002/wsbm.167

Abstract Full article on Wiley Online Library:   HTML | PDF
Mathematical models in biology: from molecules to life

Advanced Review
Yiannis N. Kaznessis
Published Online: Feb 18 2011
DOI:10.1002/wsbm.142

Abstract Full article on Wiley Online Library:   HTML | PDF
Toward a VPH/Physiome ToolKit

Overview
Alan Garny, Jonathan Cooper, Peter J. Hunter
Published Online: Sep 29 2009
DOI:10.1002/wsbm.63

Abstract Full article on Wiley Online Library:   HTML | PDF

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Philip Benfey

Philip Benfey

Is intrigued by one of the key questions in developmental biology: how cells acquire their identities. This is an important question in human development, where stem cells divide and differentiate into skin, muscle, fat etc. It is equally central to plant development, where most organs and cells are formed from stem cell populations known as meristems. The Benfey lab addresses this question using a combination of genetics, molecular biology, and genomics to identify and characterize the genes that regulate formation of the root in the plant model system, Arabidopsis thaliana. The choice of the root as a model was based on the simplicity of its organization and its stereotyped developmental program.

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