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WIREs Syst Biol Med
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Genetic/Genomic Methods

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Computational methods for analyzing and modeling genome structure and organization

Focus Article
Dejun Lin, Giancarlo Bonora, Galip Gürkan Yardımcı, William S. Noble
Published Online: Jul 18 2018
DOI:10.1002/wsbm.1435

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems analysis of dilated cardiomyopathy in the next generation sequencing era

Focus Article
Magdalena Harakalova, Folkert W. Asselbergs
Published Online: Feb 27 2018
DOI:10.1002/wsbm.1419

Abstract Full article on Wiley Online Library:   HTML | PDF
Genome organization during the cell cycle: unity in division

Focus Article
Rosela Golloshi, Jacob T. Sanders, Rachel Patton McCord
Published Online: May 16 2017
DOI:10.1002/wsbm.1389

Abstract Full article on Wiley Online Library:   HTML | PDF
Therapeutic genome engineering via CRISPR ‐Cas systems

Advanced Review
Ana M. Moreno, Prashant Mali
Published Online: Feb 15 2017
DOI:10.1002/wsbm.1380

Abstract Full article on Wiley Online Library:   HTML | PDF
Regulatory elements in molecular networks

Advanced Review
Ashley S. Doane, Olivier Elemento
Published Online: Jan 17 2017
DOI:10.1002/wsbm.1374

Abstract Full article on Wiley Online Library:   HTML | PDF
Quantitative approaches for investigating the spatial context of gene expression

Focus Article
Je H. Lee
Published Online: Dec 21 2016
DOI:10.1002/wsbm.1369

Abstract Full article on Wiley Online Library:   HTML | PDF
Data sources for in vivo molecular profiling of human phenotypes

Advanced Review
Timothy Cardozo, Priyanka Gupta, Eric Ni, Lauren M. Young, Doreen Tivon, Klara Felsovalyi
Published Online: Sep 07 2016
DOI:10.1002/wsbm.1354

Abstract Full article on Wiley Online Library:   HTML | PDF
CRISPR /Cas9 genome editing throws descriptive 3‐D genome folding studies for a loop

Advanced Review
Jonathan A. Beagan, Jennifer E. Phillips‐Cremins
Published Online: Jun 06 2016
DOI:10.1002/wsbm.1338

Abstract Full article on Wiley Online Library:   HTML | PDF
Accelerated genome engineering through multiplexing

Advanced Review
Zehua Bao, Ryan E. Cobb, Huimin Zhao
Published Online: Sep 22 2015
DOI:10.1002/wsbm.1319

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of polycystic kidney disease: a critical review

Focus Article
Luis Fernando Menezes, Gregory G. Germino
Published Online: Feb 02 2015
DOI:10.1002/wsbm.1289

Abstract Full article on Wiley Online Library:   HTML | PDF
Comparative epigenomics: defining and utilizing epigenomic variations across species, time‐course, and individuals

Opinion
Shu Xiao, Xiaoyi Cao, Sheng Zhong
Published Online: Jul 15 2014
DOI:10.1002/wsbm.1274

Abstract Full article on Wiley Online Library:   HTML | PDF
Integrating omics into the cardiac differentiation of human pluripotent stem cells

Focus Article
Agustin Rojas‐Muñoz, Mano R. Maurya, Frederick Lo, Erik Willems
Published Online: Apr 21 2014
DOI:10.1002/wsbm.1268

Abstract Full article on Wiley Online Library:   HTML | PDF
Genome network medicine: innovation to overcome huge challenges in cancer therapy

Focus Article
Dimitrios H. Roukos
Published Online: Dec 06 2013
DOI:10.1002/wsbm.1254

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology approaches to epidemiological studies of complex diseases

Opinion
Hongzhe Li
Published Online: Sep 09 2013
DOI:10.1002/wsbm.1242

Abstract Full article on Wiley Online Library:   HTML | PDF
Genomics and epigenomics of colorectal cancer

Advanced Review
Michal‐Ruth Schweiger, Michelle Hussong, Christina Röhr, Hans Lehrach
Published Online: Jan 16 2013
DOI:10.1002/wsbm.1206

Abstract Full article on Wiley Online Library:   HTML | PDF
Pharmacogenomics discovery and implementation in genome‐wide association studies era

Opinion
Xiuqin Ni, Wei Zhang, R. Stephanie Huang
Published Online: Nov 27 2012
DOI:10.1002/wsbm.1199

Abstract Full article on Wiley Online Library:   HTML | PDF
Promise of personalized omics to precision medicine

Advanced Review
Rui Chen, Michael Snyder
Published Online: Nov 26 2012
DOI:10.1002/wsbm.1198

Abstract Full article on Wiley Online Library:   HTML | PDF
Stem cell bioengineering at the interface of systems‐based models and high‐throughput platforms

Overview
Gregory H. Underhill
Published Online: Aug 23 2012
DOI:10.1002/wsbm.1189

Abstract Full article on Wiley Online Library:   HTML | PDF
Large‐scale mouse knockouts and phenotypes

Advanced Review
Ramiro Ramírez‐Solis, Edward Ryder, Richard Houghton, Jacqueline K. White, Joanna Bottomley
Published Online: Aug 15 2012
DOI:10.1002/wsbm.1183

Abstract Full article on Wiley Online Library:   HTML | PDF
Recent approaches to the prioritization of candidate disease genes

Advanced Review
Nadezhda T. Doncheva, Tim Kacprowski, Mario Albrecht
Published Online: Jun 11 2012
DOI:10.1002/wsbm.1177

Abstract Full article on Wiley Online Library:   HTML | PDF
Deciphering the complexities of human diseases and disorders by coupling induced‐pluripotent stem cells and systems genetics

Advanced Review
Wing Y. Chang, Kamal Garcha, Janet L. Manias, William L. Stanford
Published Online: Apr 10 2012
DOI:10.1002/wsbm.1170

Abstract Full article on Wiley Online Library:   HTML | PDF
Potential role of atomic force microscopy in systems biology

Advanced Review
Srinivasan Ramachandran, Fernando Teran Arce, Ratnesh Lal
Published Online: Jul 15 2011
DOI:10.1002/wsbm.154

Abstract Full article on Wiley Online Library:   HTML | PDF
Postgenomic technologies targeting the Wnt signaling network

Advanced Review
Raluca Pancratov, Ramanuj DasGupta
Published Online: Mar 04 2011
DOI:10.1002/wsbm.140

Abstract Full article on Wiley Online Library:   HTML | PDF
Genome‐wide approaches in the study of microRNA biology

Advanced Review
Melissa L. Wilbert, Gene W. Yeo
Published Online: Dec 31 2010
DOI:10.1002/wsbm.128

Abstract Full article on Wiley Online Library:   HTML | PDF
Layers of epistasis: genome‐wide regulatory networks and network approaches to genome‐wide association studies

Advanced Review
Richard Cowper‐Sal·lari, Michael D. Cole, Margaret R. Karagas, Mathieu Lupien, Jason H. Moore
Published Online: Dec 31 2010
DOI:10.1002/wsbm.132

Abstract Full article on Wiley Online Library:   HTML | PDF
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