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WIREs Syst Biol Med
Impact Factor: 3.542

Translational Medicine

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Molecular networks in Network Medicine: Development and applications

Advanced Review
Edwin K. Silverman, Harald H. H. W. Schmidt, Eleni Anastasiadou, Lucia Altucci, Marco Angelini, Lina Badimon, Jean‐Luc Balligand, Giuditta Benincasa, Giovambattista Capasso, Federica Conte, Antonella Di Costanzo, Lorenzo Farina, Giulia Fiscon, Laurent Gatto, Michele Gentili, Joseph Loscalzo, Cinzia Marchese, Claudio Napoli, Paola Paci, Manuela Petti, John Quackenbush, Paolo Tieri, Davide Viggiano, Gemma Vilahur, Kimberly Glass, Jan Baumbach
Published Online: Apr 20 2020
DOI:10.1002/wsbm.1489

Abstract Full article on Wiley Online Library:   HTML | PDF
The immunologic Warburg effect: Evidence and therapeutic opportunities in autoimmunity

Advanced Review
Michael D. Kornberg
Published Online: Feb 27 2020
DOI:10.1002/wsbm.1486

Abstract Full article on Wiley Online Library:   HTML | PDF
Glucose transporter 1 in rheumatoid arthritis and autoimmunity

Advanced Review
Nadine Biesemann, Matthias Herrmann, Oezen Sercan‐Alp, Ekaterina Zezina
Published Online: Feb 21 2020
DOI:10.1002/wsbm.1483

Abstract Full article on Wiley Online Library:   HTML | PDF
How personalized heart modeling can help treatment of lethal arrhythmias: A focus on ventricular tachycardia ablation strategies in post‐infarction patients

Advanced Review
Natalia A. Trayanova, Ashish N. Doshi, Adityo Prakosa
Published Online: Jan 09 2020
DOI:10.1002/wsbm.1477

Abstract Full article on Wiley Online Library:   HTML | PDF
Structural neuroimaging of the altered brain stemming from pediatric and adolescent hearing loss—Scientific and clinical challenges

Advanced Review
J. Tilak Ratnanather
Published Online: Dec 04 2019
DOI:10.1002/wsbm.1469

Abstract Full article on Wiley Online Library:   HTML | PDF
Agent‐based models of inflammation in translational systems biology: A decade later

UPDATE
Gary An, Yoram Vodovotz
Published Online: Jul 01 2019
DOI:10.1002/wsbm.1460

Abstract Full article on Wiley Online Library:   HTML | PDF
Integrating molecular networks with genetic variant interpretation for precision medicine

Overview
Emidio Capriotti, Kivilcim Ozturk, Hannah Carter
Published Online: Dec 12 2018
DOI:10.1002/wsbm.1443

Abstract Full article on Wiley Online Library:   HTML | PDF
PharmGKB: A worldwide resource for pharmacogenomic information

Advanced Review
Teri E. Klein, Russ B. Altman, Michelle Whirl‐Carrillo, Julia M. Barbarino
Published Online: Feb 23 2018
DOI:10.1002/wsbm.1417

Abstract Full article on Wiley Online Library:   HTML | PDF
Human microbiota, blood group antigens, and disease

Advanced Review
D. Rose Ewald, Susan C.J. Sumner
Published Online: Jan 09 2018
DOI:10.1002/wsbm.1413

Abstract Full article on Wiley Online Library:   HTML | PDF
Biomechanics of the human uterus

Focus Article
Kristin M. Myers, David Elad
Published Online: May 12 2017
DOI:10.1002/wsbm.1388

Abstract Full article on Wiley Online Library:   HTML | PDF
Integrated precision medicine: the role of electronic health records in delivering personalized treatment

Focus Article
Amy Sitapati, Hyeoneui Kim, Barbara Berkovich, Rebecca Marmor, Siddharth Singh, Robert El‐Kareh, Brian Clay, Lucila Ohno‐Machado
Published Online: Feb 16 2017
DOI:10.1002/wsbm.1378

Abstract Full article on Wiley Online Library:   HTML | PDF
Modified mRNA as a therapeutic tool to induce cardiac regeneration in ischemic heart disease

Focus Article
Yoav Hadas, Michael G. Katz, Charles R. Bridges, Lior Zangi
Published Online: Dec 02 2016
DOI:10.1002/wsbm.1367

Abstract Full article on Wiley Online Library:   HTML | PDF
Computational approaches for the identification of cancer genes and pathways

Advanced Review
Christos M. Dimitrakopoulos, Niko Beerenwinkel
Published Online: Nov 11 2016
DOI:10.1002/wsbm.1364

Abstract Full article on Wiley Online Library:   HTML | PDF
Engineering of synthetic gene circuits for (re‐)balancing physiological processes in chronic diseases

Advanced Review
Lina Schukur, Martin Fussenegger
Published Online: Jun 24 2016
DOI:10.1002/wsbm.1345

Abstract Full article on Wiley Online Library:   HTML | PDF
Mathematical models of breast and ovarian cancers

Advanced Review
Dana‐Adriana Botesteanu, Stanley Lipkowitz, Jung‐Min Lee, Doron Levy
Published Online: Jun 03 2016
DOI:10.1002/wsbm.1343

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems medicine in colorectal cancer: from a mathematical model toward a new type of clinical trial

Advanced Review
Nicoletta Castagnino, Massimo Maffei, Lorenzo Tortolina, Gabriele Zoppoli, Daniela Piras, Alessio Nencioni, Eva Moran, Alberto Ballestrero, Franco Patrone, Silvio Parodi
Published Online: May 30 2016
DOI:10.1002/wsbm.1342

Abstract Full article on Wiley Online Library:   HTML | PDF
In silico methods for drug repurposing and pharmacology

Overview
Rachel A. Hodos, Brian A. Kidd, Khader Shameer, Ben P. Readhead, Joel T. Dudley
Published Online: Apr 15 2016
DOI:10.1002/wsbm.1337

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology approaches for identifying adverse drug reactions and elucidating their underlying biological mechanisms

Advanced Review
Nicholas P. Tatonetti, Robert Moskovitch, Joseph D. Romano, Tal Lorberbaum, Alexandra Jacunski, Mary Regina Boland
Published Online: Nov 12 2015
DOI:10.1002/wsbm.1323

Abstract Full article on Wiley Online Library:   HTML | PDF
Integrative biomarker discovery in neurodegenerative diseases

Overview
André V. Carreiro, Alexandre Mendonça, Mamede de Carvalho, Sara C. Madeira
Published Online: Jul 02 2015
DOI:10.1002/wsbm.1310

Abstract Full article on Wiley Online Library:   HTML | PDF
Genome‐wide association studies in biliary atresia

Advanced Review
Mylarappa Ningappa, Jun Min, Brandon W. Higgs, Chethan Ashokkumar, Sarangarajan Ranganathan, Rakesh Sindhi
Published Online: May 11 2015
DOI:10.1002/wsbm.1303

Abstract Full article on Wiley Online Library:   HTML | PDF
Parsing interindividual drug variability: an emerging role for systems pharmacology

Advanced Review
Richard M. Turner, B. Kevin Park, Munir Pirmohamed
Published Online: May 07 2015
DOI:10.1002/wsbm.1302

Abstract Full article on Wiley Online Library:   HTML | PDF
Network pharmacodynamic models for customized cancer therapy

Focus Article
James M. Gallo, Marc R. Birtwistle
Published Online: Apr 24 2015
DOI:10.1002/wsbm.1300

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems medicine: evolution of systems biology from bench to bedside

Overview
Rui‐Sheng Wang, Bradley A. Maron, Joseph Loscalzo
Published Online: Apr 17 2015
DOI:10.1002/wsbm.1297

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems engineering meets quantitative systems pharmacology: from low‐level targets to engaging the host defenses

Opinion
Ioannis P. Androulakis
Published Online: Mar 16 2015
DOI:10.1002/wsbm.1294

Abstract Full article on Wiley Online Library:   HTML | PDF
A practical model for economic evaluation of tissue‐engineered therapies

Focus Article
Tien‐En Tan, Gary S. L. Peh, Eric A. Finkelstein, Jodhbir S. Mehta
Published Online: Feb 17 2015
DOI:10.1002/wsbm.1292

Abstract Full article on Wiley Online Library:   HTML | PDF
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