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WIREs Syst Biol Med
Impact Factor: 3.542

Translational Medicine

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Advances in modeling ventricular arrhythmias: from mechanisms to the clinic

Focus Article
Natalia A. Trayanova, Patrick M. Boyle
Published Online: Dec 06 2013
DOI:10.1002/wsbm.1256

Abstract Full article on Wiley Online Library:   HTML | PDF
Using systems biology approaches to understand cardiac inflammation and extracellular matrix remodeling in the setting of myocardial infarction

Advanced Review
Omid Ghasemi, Yonggang Ma, Merry L. Lindsey, Yu‐Fang Jin
Published Online: Nov 08 2013
DOI:10.1002/wsbm.1248

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology‐embedded target validation: improving efficacy in drug discovery

Opinion
Walter Kolch, Boris N. Kholodenko, William Fitzmaurice, Benedikt A. Minke, Drieke Vandamme
Published Online: Nov 08 2013
DOI:10.1002/wsbm.1253

Abstract Full article on Wiley Online Library:   HTML | PDF
Vascular tissue engineering: from in vitro to in situ

Advanced Review
Song Li, Debanti Sengupta, Shu Chien
Published Online: Oct 22 2013
DOI:10.1002/wsbm.1246

Abstract Full article on Wiley Online Library:   HTML | PDF
Agent‐based modeling: a systematic assessment of use cases and requirements for enhancing pharmaceutical research and development productivity

Advanced Review
C. Anthony Hunt, Ryan C. Kennedy, Sean H. J. Kim, Glen E. P. Ropella
Published Online: Jun 04 2013
DOI:10.1002/wsbm.1222

Abstract Full article on Wiley Online Library:   HTML | PDF
Branched‐chain amino acid supplementation: impact on signaling and relevance to critical illness

Advanced Review
John S. A. Mattick, Kubra Kamisoglu, Marianthi G. Ierapetritou, Ioannis P. Androulakis, Francois Berthiaume
Published Online: Mar 29 2013
DOI:10.1002/wsbm.1219

Abstract Full article on Wiley Online Library:   HTML | PDF
Lower urinary tract development and disease

Advanced Review
Hila Milo Rasouly, Weining Lu
Published Online: Feb 13 2013
DOI:10.1002/wsbm.1212

Abstract Full article on Wiley Online Library:   HTML | PDF
Genomics and epigenomics of colorectal cancer

Advanced Review
Michal‐Ruth Schweiger, Michelle Hussong, Christina Röhr, Hans Lehrach
Published Online: Jan 16 2013
DOI:10.1002/wsbm.1206

Abstract Full article on Wiley Online Library:   HTML | PDF
Can a systems biology approach unlock the mysteries of Kawasaki disease?

Focus Article
Anne H. Rowley
Published Online: Jan 04 2013
DOI:10.1002/wsbm.1202

Abstract Full article on Wiley Online Library:   HTML | PDF
Pharmacogenomics discovery and implementation in genome‐wide association studies era

Opinion
Xiuqin Ni, Wei Zhang, R. Stephanie Huang
Published Online: Nov 27 2012
DOI:10.1002/wsbm.1199

Abstract Full article on Wiley Online Library:   HTML | PDF
Promise of personalized omics to precision medicine

Advanced Review
Michael Snyder, Rui Chen
Published Online: Nov 26 2012
DOI:10.1002/wsbm.1198

Abstract Full article on Wiley Online Library:   HTML | PDF
Mechanisms of memory enhancement

Advanced Review
Sarah A. Stern, Cristina M. Alberini
Published Online: Nov 13 2012
DOI:10.1002/wsbm.1196

Abstract Full article on Wiley Online Library:   HTML | PDF
Stem cell bioengineering at the interface of systems‐based models and high‐throughput platforms

Overview
Gregory H. Underhill
Published Online: Aug 23 2012
DOI:10.1002/wsbm.1189

Abstract Full article on Wiley Online Library:   HTML | PDF
From base pair to bedside: molecular simulation and the translation of genomics to personalized medicine

Advanced Review
David W. Wright, Shunzhou Wan, Nour Shublaq, Stefan J. Zasada, Peter V. Coveney
Published Online: Aug 15 2012
DOI:10.1002/wsbm.1186

Abstract Full article on Wiley Online Library:   HTML | PDF
The role of regulatory T cells in neurodegenerative diseases

Advanced Review
Feng He, Rudi Balling
Published Online: Aug 15 2012
DOI:10.1002/wsbm.1187

Abstract Full article on Wiley Online Library:   HTML | PDF
Recent approaches to the prioritization of candidate disease genes

Advanced Review
Nadezhda T. Doncheva, Tim Kacprowski, Mario Albrecht
Published Online: Jun 11 2012
DOI:10.1002/wsbm.1177

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems pharmacology, pharmacogenetics, and clinical trial design in network medicine

Advanced Review
Joseph Loscalzo, Scott Weiss, Elliott Antman
Published Online: May 11 2012
DOI:10.1002/wsbm.1173

Abstract Full article on Wiley Online Library:   HTML | PDF
Deciphering the complexities of human diseases and disorders by coupling induced‐pluripotent stem cells and systems genetics

Advanced Review
Wing Y. Chang, Kamal Garcha, Janet L. Manias, William L. Stanford
Published Online: Apr 10 2012
DOI:10.1002/wsbm.1170

Abstract Full article on Wiley Online Library:   HTML | PDF
Integration of proteomics into systems biology of cancer

Advanced Review
A. Taguchi, Q. Zhang, M. Schliekelman, S. Hanash
Published Online: Mar 08 2012
DOI:10.1002/wsbm.1169

Abstract Full article on Wiley Online Library:   HTML | PDF
The virtual liver: a multidisciplinary, multilevel challenge for systems biology

Overview
Hermann‐Georg Holzhütter, Dirk Drasdo, Tobias Preusser, Jörg Lippert, Adriano M. Henney
Published Online: Jan 13 2012
DOI:10.1002/wsbm.1158

Abstract Full article on Wiley Online Library:   HTML | PDF
Engineered tissue grafts: opportunities and challenges in regenerative medicine

Focus Article
Adam W. Feinberg
Published Online: Oct 19 2011
DOI:10.1002/wsbm.164

Abstract Full article on Wiley Online Library:   HTML | PDF
A systems biology approach to synovial joint lubrication in health, injury, and disease

Overview
Alexander Y. Hui, William J. McCarty, Koichi Masuda, Gary S. Firestein, Robert L. Sah
Published Online: Aug 08 2011
DOI:10.1002/wsbm.157

Abstract Full article on Wiley Online Library:   HTML | PDF
Pathways, networks, and systems medicine—the meeting place of the Aegean and the mind

Editorial Commentary
Shankar Subramaniam, Joseph H. Nadeau
Published Online: Apr 01 2011
DOI:10.1002/wsbm.153

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology and the future of medicine

Opinion
Joseph Loscalzo, Albert‐Laszlo Barabasi
Published Online: Feb 24 2011
DOI:10.1002/wsbm.144

Abstract Full article on Wiley Online Library:   HTML | PDF
Estrogen receptor‐positive breast cancer: a multidisciplinary challenge

Focus Article
Wilbert Zwart, Vasiliki Theodorou, Jason S. Carroll
Published Online: Feb 08 2011
DOI:10.1002/wsbm.109

Abstract Full article on Wiley Online Library:   HTML | PDF
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