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Therapeutic Methods

Hybrid modeling frameworks of tumor development and treatment

UPDATE
Katarzyna A. Rejniak, Ibrahim M. Chamseddine
Published Online: Jul 17 2019
DOI:10.1002/wsbm.1461

Abstract Full article on Wiley Online Library:   HTML | PDF
Context‐dependent regulation of receptor tyrosine kinases: Insights from systems biology approaches

Focus Article
Inez Lam, Christina M. Pickering, Feilim Mac Gabhann
Published Online: Sep 26 2018
DOI:10.1002/wsbm.1437

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems approaches to optimizing deep brain stimulation therapies in Parkinson’s disease

Overview
Sabato Santaniello, John T. Gale, Sridevi V. Sarma
Published Online: Mar 20 2018
DOI:10.1002/wsbm.1421

Abstract Full article on Wiley Online Library:   HTML | PDF
Therapeutic genome engineering via CRISPR‐Cas systems

Advanced Review
Prashant Mali, Ana M. Moreno
Published Online: Feb 15 2017
DOI:10.1002/wsbm.1380

Abstract Full article on Wiley Online Library:   HTML | PDF
Modified mRNA as a therapeutic tool to induce cardiac regeneration in ischemic heart disease

Focus Article
Yoav Hadas, Michael G. Katz, Charles R. Bridges, Lior Zangi
Published Online: Dec 02 2016
DOI:10.1002/wsbm.1367

Abstract Full article on Wiley Online Library:   HTML | PDF
Omics‐based approaches to understand mechanosensitive endothelial biology and atherosclerosis

Advanced Review
Rachel D. Simmons, Sandeep Kumar, Salim Raid Thabet, Sanjoli Sur, Hanjoong Jo
Published Online: Jun 24 2016
DOI:10.1002/wsbm.1344

Abstract Full article on Wiley Online Library:   HTML | PDF
Engineering of synthetic gene circuits for (re‐)balancing physiological processes in chronic diseases

Advanced Review
Lina Schukur, Martin Fussenegger
Published Online: Jun 24 2016
DOI:10.1002/wsbm.1345

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems approaches to design of targeted therapeutic delivery

Overview
Jacob W. Myerson, Jacob S. Brenner, Colin F. Greineder, Vladimir R. Muzykantov
Published Online: May 06 2015
DOI:10.1002/wsbm.1304

Abstract Full article on Wiley Online Library:   HTML | PDF
Genome network medicine: innovation to overcome huge challenges in cancer therapy

Focus Article
Dimitrios H. Roukos
Published Online: Dec 06 2013
DOI:10.1002/wsbm.1254

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology‐embedded target validation: improving efficacy in drug discovery

Opinion
Walter Kolch, Boris N. Kholodenko, William Fitzmaurice, Benedikt A. Minke, Drieke Vandamme
Published Online: Nov 08 2013
DOI:10.1002/wsbm.1253

Abstract Full article on Wiley Online Library:   HTML | PDF
Vascular tissue engineering: from in vitro to in situ

Advanced Review
Shu Chien, Debanti Sengupta, Song Li
Published Online: Oct 22 2013
DOI:10.1002/wsbm.1246

Abstract Full article on Wiley Online Library:   HTML | PDF
Mathematical modeling of folate metabolism

Focus Article
John C. Panetta, Steven W. Paugh, William E. Evans
Published Online: May 22 2013
DOI:10.1002/wsbm.1227

Abstract Full article on Wiley Online Library:   HTML | PDF
Developing melanoma therapeutics: overview and update

Overview
John B. Korman, David E. Fisher
Published Online: Feb 13 2013
DOI:10.1002/wsbm.1210

Abstract Full article on Wiley Online Library:   HTML | PDF
Genomics and epigenomics of colorectal cancer

Advanced Review
Michal‐Ruth Schweiger, Michelle Hussong, Christina Röhr, Hans Lehrach
Published Online: Jan 16 2013
DOI:10.1002/wsbm.1206

Abstract Full article on Wiley Online Library:   HTML | PDF
Mechanisms of memory enhancement

Advanced Review
Cristina M. Alberini, Sarah A. Stern
Published Online: Nov 13 2012
DOI:10.1002/wsbm.1196

Abstract Full article on Wiley Online Library:   HTML | PDF
The role of regulatory T cells in neurodegenerative diseases

Advanced Review
Feng He, Rudi Balling
Published Online: Aug 15 2012
DOI:10.1002/wsbm.1187

Abstract Full article on Wiley Online Library:   HTML | PDF
Engineered tissue grafts: opportunities and challenges in regenerative medicine

Focus Article
Adam W. Feinberg
Published Online: Oct 19 2011
DOI:10.1002/wsbm.164

Abstract Full article on Wiley Online Library:   HTML | PDF
Role of systems pharmacology in understanding drug adverse events

Opinion
Seth I. Berger, Ravi Iyengar
Published Online: Aug 27 2010
DOI:10.1002/wsbm.114

Abstract Full article on Wiley Online Library:   HTML | PDF
Emerging clinical applications in cardiovascular pharmacogenomics

Advanced Review
Samir B. Damani, Eric J. Topol
Published Online: Aug 20 2010
DOI:10.1002/wsbm.113

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems analysis of salivary gland development and disease

Advanced Review
Melinda Larsen, Kenneth M. Yamada, Kurt Musselmann
Published Online: Apr 01 2010
DOI:10.1002/wsbm.94

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems approaches and algorithms for discovery of combinatorial therapies

Advanced Review
Jacob D. Feala, Jorge Cortes, Phillip M. Duxbury, Carlo Piermarocchi, Andrew D. McCulloch, Giovanni Paternostro
Published Online: Mar 26 2010
DOI:10.1002/wsbm.51

Abstract Full article on Wiley Online Library:   HTML | PDF
The network as the target

Opinion
Julie E. Baggs, Michael E. Hughes, John B. Hogenesch
Published Online: Mar 26 2010
DOI:10.1002/wsbm.57

Abstract Full article on Wiley Online Library:   HTML | PDF

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