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RNA in Disease

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The role of RNA G‐quadruplexes in human diseases and therapeutic strategies

Overview
Soumitra Basu, Nathan Beals, Sumirtha Balaratnam, Prakash Kharel
Published Online: Sep 12 2019
DOI:10.1002/wrna.1568

Abstract Full article on Wiley Online Library:   HTML | PDF
Highlighting transcribed ultraconserved regions in human diseases

Advanced Review
Jaqueline Carvalho de Oliveira, George A. Calin, Daniela Fiori Gradia, Enilze M. Souza Fonseca Ribeiro, Ana Carolina Rodrigues, Carolina Mathias, Erika Pereira Zambalde
Published Online: Sep 05 2019
DOI:10.1002/wrna.1567

Abstract Full article on Wiley Online Library:   HTML | PDF
Cluster miRNAs and cancer: Diagnostic, prognostic and therapeutic opportunities

Advanced Review
Shama Prasada Kabekkodu, Vaibhav Shukla, Vinay Koshy Varghese, Divya Adiga, Padacherri Vethil Jishnu, Sanjiban Chakrabarty, Kapaettu Satyamoorthy
Published Online: Aug 22 2019
DOI:10.1002/wrna.1563

Abstract Full article on Wiley Online Library:   HTML | PDF
Fusion transcripts: Unexploited vulnerabilities in cancer?

Opinion
Carla Neckles, Soumya Sundara Rajan, Natasha J. Caplen
Published Online: Aug 13 2019
DOI:10.1002/wrna.1562

Abstract Full article on Wiley Online Library:   HTML | PDF
How to get away with nonsense: Mechanisms and consequences of escape from nonsense‐mediated RNA decay

Advanced Review
Sujatha Jagannathan, Michael A. Cortazar, Divya Kolakada, Michael C. Dyle
Published Online: Jul 29 2019
DOI:10.1002/wrna.1560

Abstract Full article on Wiley Online Library:   HTML | PDF
RNA control in pain: Blame it on the messenger

Overview
June Bryan I. Peña, Jane J. Song, Zachary T. Campbell
Published Online: May 14 2019
DOI:10.1002/wrna.1546

Abstract Full article on Wiley Online Library:   HTML | PDF
Alternative polyadenylation and the stress response

Advanced Review
Jason Sadek, Amr Omer, Derek Hall, Kholoud Ashour, Imed Eddine Gallouzi
Published Online: May 02 2019
DOI:10.1002/wrna.1540

Abstract Full article on Wiley Online Library:   HTML | PDF
RNA regulatory processes in RNA virus biology

Advanced Review
Shaun T. Cross, Daniel Michalski, Megan R. Miller, Jeffrey Wilusz
Published Online: Apr 29 2019
DOI:10.1002/wrna.1536

Abstract Full article on Wiley Online Library:   HTML | PDF
Intriguing circles: Conflicts and controversies in circular RNA research

Advanced Review
Hui‐Min Li, Xiu‐Lan Ma, Hong‐Gang Li
Published Online: Apr 29 2019
DOI:10.1002/wrna.1538

Abstract Full article on Wiley Online Library:   HTML | PDF
Viral modulation of cellular RNA alternative splicing: A new key player in virus–host interactions?

Advanced Review
Simon Boudreault, Patricia Roy, Guy Lemay, Martin Bisaillon
Published Online: Apr 29 2019
DOI:10.1002/wrna.1543

Abstract Full article on Wiley Online Library:   HTML | PDF
RNA regulation of the antiviral protein 2′‐5′‐oligoadenylate synthetase

Focus Article
Samantha L. Schwartz, Graeme L. Conn
Published Online: Apr 15 2019
DOI:10.1002/wrna.1534

Abstract Full article on Wiley Online Library:   HTML | PDF
Extracellular RNA in viral–host interactions: Thinking outside the cell

Advanced Review
Sarah Ressel, Adelina Rosca, Katrina Gordon, Amy H. Buck
Published Online: Apr 08 2019
DOI:10.1002/wrna.1535

Abstract Full article on Wiley Online Library:   HTML | PDF
Splicing and neurodegeneration: Insights and mechanisms

Advanced Review
Sara Nik, Teresa V. Bowman
Published Online: Mar 20 2019
DOI:10.1002/wrna.1532

Abstract Full article on Wiley Online Library:   HTML | PDF
miR‐146a‐5p: Expression, regulation, and functions in cancer

Advanced Review
Carol S. Lutz, Joseph R. Iacona
Published Online: Mar 20 2019
DOI:10.1002/wrna.1533

Abstract Full article on Wiley Online Library:   HTML | PDF
Splicing and cancer: Challenges and opportunities

Advanced Review
Patricia P. Coltri, Maria G.P. dos Santos, Guilherme H.G. da Silva
Published Online: Feb 17 2019
DOI:10.1002/wrna.1527

Abstract Full article on Wiley Online Library:   HTML | PDF
Diverse roles of RNA‐binding proteins in cancer traits and their implications in gastrointestinal cancers

Advanced Review
Kiyoshi Masuda, Yuki Kuwano
Published Online: Nov 26 2018
DOI:10.1002/wrna.1520

Abstract Full article on Wiley Online Library:   HTML | PDF
Dynamic and reversible RNA N6‐methyladenosine methylation

Focus Article
Guifang Jia, Ye Wang, Hong‐Chao Duan
Published Online: Sep 25 2018
DOI:10.1002/wrna.1507

Abstract Full article on Wiley Online Library:   HTML | PDF
Toxins targeting transfer RNAs: Translation inhibition by bacterial toxin–antitoxin systems

Advanced Review
Lauren R. Walling, J. Scott Butler
Published Online: Sep 16 2018
DOI:10.1002/wrna.1506

Abstract Full article on Wiley Online Library:   HTML | PDF
Glycogen synthase kinase‐3 and alternative splicing

Advanced Review
Xiaolei Liu, Peter S. Klein
Published Online: Aug 17 2018
DOI:10.1002/wrna.1501

Abstract Full article on Wiley Online Library:   HTML | PDF
Unconventional RNA‐binding proteins step into the virus–host battlefront

Advanced Review
Manuel Garcia‐Moreno, Aino I. Järvelin, Alfredo Castello
Published Online: Aug 09 2018
DOI:10.1002/wrna.1498

Abstract Full article on Wiley Online Library:   HTML | PDF
Ataxin‐2: A versatile posttranscriptional regulator and its implication in neural function

Focus Article
Jongbo Lee, Minjong Kim, Taichi Q. Itoh, Chunghun Lim
Published Online: Jun 05 2018
DOI:10.1002/wrna.1488

Abstract Full article on Wiley Online Library:   HTML | PDF
Targeting RNA in mammalian systems with small molecules

Advanced Review
Amanda E. Hargrove, Anita Donlic
Published Online: May 03 2018
DOI:10.1002/wrna.1477

Abstract Full article on Wiley Online Library:   HTML | PDF
Alternative‐splicing defects in cancer: Splicing regulators and their downstream targets, guiding the way to novel cancer therapeutics

Advanced Review
Olga Anczuków, Nathan Leclair, Laura M. Urbanski
Published Online: Apr 25 2018
DOI:10.1002/wrna.1476

Abstract Full article on Wiley Online Library:   HTML | PDF
Genetic variants in mRNA untranslated regions

Overview
Valeria Orrù, Michael B. Whalen, M. Laura Idda, Maristella Steri
Published Online: Mar 26 2018
DOI:10.1002/wrna.1474

Abstract Full article on Wiley Online Library:   HTML | PDF
Complex HuR function in pancreatic cancer cells

Focus Article
Dan A. Dixon, Jonathan R. Brody
Published Online: Feb 16 2018
DOI:10.1002/wrna.1469

Abstract Full article on Wiley Online Library:   HTML | PDF
Therapeutic applications of group I intron‐based trans‐splicing ribozymes

Advanced Review
Chang Ho Lee, Seung Ryul Han, Seong‐Wook Lee
Published Online: Jan 31 2018
DOI:10.1002/wrna.1466

Abstract Full article on Wiley Online Library:   HTML | PDF
Natural antisense transcripts in diseases: From modes of action to targeted therapies

Advanced Review
Michał Wojciech Szcześniak, Izabela Makałowska, Wojciech Rosikiewicz, Magdalena Regina Kubiak, Elżbieta Wanowska
Published Online: Jan 17 2018
DOI:10.1002/wrna.1461

Abstract Full article on Wiley Online Library:   HTML | PDF
Noncoding RNAs in Alzheimer's disease

Advanced Review
Myriam Gorospe, Kotb Abdelmohsen, Rachel Munk, M. Laura Idda
Published Online: Jan 12 2018
DOI:10.1002/wrna.1463

Abstract Full article on Wiley Online Library:   HTML | PDF
Cold‐inducible RNA binding protein in cancer and inflammation

Focus Article
Daniel A. Lujan, Joey L. Ochoa, Rebecca S. Hartley
Published Online: Jan 11 2018
DOI:10.1002/wrna.1462

Abstract Full article on Wiley Online Library:   HTML | PDF
Emerging roles of RNA‐binding proteins in diabetes and their therapeutic potential in diabetic complications

Advanced Review
Curtis A. Nutter, Muge N. Kuyumcu‐Martinez
Published Online: Dec 27 2017
DOI:10.1002/wrna.1459

Abstract Full article on Wiley Online Library:   HTML | PDF
RNA versatility, flexibility, and thermostability for practice in RNA nanotechnology and biomedical applications

Advanced Review
Farzin Haque, Fengmei Pi, Zhengyi Zhao, Shanqing Gu, Haibo Hu, Hang Yu, Peixuan Guo
Published Online: Nov 03 2017
DOI:10.1002/wrna.1452

Abstract Full article on Wiley Online Library:   HTML | PDF
Cyclic‐di‐GMP regulation of virulence in bacterial pathogens

Overview
Vincent T. Lee, Cherisse L. Hall
Published Online: Oct 08 2017
DOI:10.1002/wrna.1454

Abstract Full article on Wiley Online Library:   HTML | PDF
Regulation and function of CMTR1‐dependent mRNA cap methylation

Advanced Review
Francisco Inesta‐Vaquera, Victoria H Cowling
Published Online: Oct 02 2017
DOI:10.1002/wrna.1450

Abstract Full article on Wiley Online Library:   HTML | PDF
Rules and tools to predict the splicing effects of exonic and intronic mutations

Advanced Review
Akio Masuda, Jun‐ichi Takeda, Kinji Ohno
Published Online: Sep 26 2017
DOI:10.1002/wrna.1451

Abstract Full article on Wiley Online Library:   HTML | PDF
Endonuclease Regnase‐1/Monocyte chemotactic protein‐1‐induced protein‐1 (MCPIP1) in controlling immune responses and beyond

Advanced Review
Osamu Takeuchi
Published Online: Sep 20 2017
DOI:10.1002/wrna.1449

Abstract Full article on Wiley Online Library:   HTML | PDF
Microbes and RNA – Not Something to Sneeze At

Editorial Commentary
Jeffrey Wilusz
Published Online: Aug 17 2017
DOI:10.1002/wrna.1439

Abstract Full article on Wiley Online Library:   HTML | PDF
Organization of the Flavivirus RNA replicase complex

Advanced Review
Carolin Brand, Martin Bisaillon, Brian J. Geiss
Published Online: Aug 16 2017
DOI:10.1002/wrna.1437

Abstract Full article on Wiley Online Library:   HTML | PDF
Urinary microRNAs for prostate cancer diagnosis, prognosis, and treatment response: are we there yet?

Advanced Review
Ovidiu Balacescu, Bogdan Petrut, Oana Tudoran, Dragos Feflea, Loredana Balacescu, Andrei Anghel, Ioan O. Sirbu, Edward Seclaman, Catalin Marian
Published Online: Aug 16 2017
DOI:10.1002/wrna.1438

Abstract Full article on Wiley Online Library:   HTML | PDF
Ancient and modern: hints of a core post‐transcriptional network driving chemotherapy resistance in ovarian cancer

Focus Article
Sarah Blagden, Mai Abdel Mouti, James Chettle
Published Online: Aug 01 2017
DOI:10.1002/wrna.1432

Abstract Full article on Wiley Online Library:   HTML | PDF
Discovery and function of transfer RNA‐derived fragments and their role in disease

Focus Article
Manuel Santos, Ana Raquel Soares
Published Online: Jun 12 2017
DOI:10.1002/wrna.1423

Abstract Full article on Wiley Online Library:   HTML | PDF
Chimeric RNAs in cancer and normal physiology

Advanced Review
Katarzyna Chwalenia, Loryn Facemire, Hui Li
Published Online: Jun 07 2017
DOI:10.1002/wrna.1427

Abstract Full article on Wiley Online Library:   HTML | PDF
Box C/D small nucleolar RNA genes and the Prader‐Willi syndrome: a complex interplay

Advanced Review
Jérôme Cavaillé
Published Online: Mar 13 2017
DOI:10.1002/wrna.1417

Abstract Full article on Wiley Online Library:   HTML | PDF
Cell cycle RNA regulons coordinating early lymphocyte development

Focus Article
Alison Galloway, Martin Turner
Published Online: Feb 23 2017
DOI:10.1002/wrna.1419

Abstract Full article on Wiley Online Library:   HTML | PDF
Microexons: discovery, regulation, and function

Advanced Review
Dmytro Ustianenko, Sebastien M. Weyn‐Vanhentenryck, Chaolin Zhang
Published Online: Feb 11 2017
DOI:10.1002/wrna.1418

Abstract Full article on Wiley Online Library:   HTML | PDF
Structures of RNA repeats associated with neurological diseases

Overview
Agnieszka Kiliszek, Wojciech Rypniewski, Leszek Błaszczyk
Published Online: Jan 28 2017
DOI:10.1002/wrna.1412

Abstract Full article on Wiley Online Library:   HTML | PDF
Regulation of mRNA following brain ischemia and reperfusion

Advanced Review
Donald J. DeGracia
Published Online: Jan 17 2017
DOI:10.1002/wrna.1415

Abstract Full article on Wiley Online Library:   HTML | PDF
Long noncoding RNAs in the p53 network

Advanced Review
Ritu Chaudhary, Ashish Lal
Published Online: Dec 19 2016
DOI:10.1002/wrna.1410

Abstract Full article on Wiley Online Library:   HTML | PDF
Current progress on microRNAs‐based therapeutics in neurodegenerative diseases

Advanced Review
Patrícia Pereira, João A. Queiroz, Ana Figueiras, Fani Sousa
Published Online: Nov 24 2016
DOI:10.1002/wrna.1409

Abstract Full article on Wiley Online Library:   HTML | PDF
Regulation of mRNA turnover in cystic fibrosis lung disease

Focus Article
Harvey B. Pollard, Parameet Kumar, Roopa Biswas
Published Online: Nov 13 2016
DOI:10.1002/wrna.1408

Abstract Full article on Wiley Online Library:   HTML | PDF
Posttranscriptional regulation of intestinal epithelial integrity by noncoding RNAs

Focus Article
Jun‐Yao Wang, Lan Xiao, Jian‐Ying Wang
Published Online: Oct 04 2016
DOI:10.1002/wrna.1399

Abstract Full article on Wiley Online Library:   HTML | PDF
RNA‐binding proteins implicated in neurodegenerative diseases

Focus Article
Mark R Cookson
Published Online: Sep 23 2016
DOI:10.1002/wrna.1397

Abstract Full article on Wiley Online Library:   HTML | PDF
Neurodegeneration and RNA‐binding proteins

Advanced Review
Laura De Conti, Marco Baralle, Emanuele Buratti
Published Online: Sep 22 2016
DOI:10.1002/wrna.1394

Abstract Full article on Wiley Online Library:   HTML | PDF
Extracellular RNA in aging

Overview
Douglas F. Dluzen, Nicole Noren Hooten, Michele K. Evans
Published Online: Aug 17 2016
DOI:10.1002/wrna.1385

Abstract Full article on Wiley Online Library:   HTML | PDF
Advances in the characterization of RNA‐binding proteins

Advanced Review
Domenica Marchese, Natalia Sanchez de Groot, Nieves Lorenzo Gotor, Carmen Maria Livi, Gian G. Tartaglia
Published Online: Aug 08 2016
DOI:10.1002/wrna.1378

Abstract Full article on Wiley Online Library:   HTML | PDF
Roles of long noncoding RNAs in chromosome domains

Advanced Review
Saori Tomita, Mohamed Osama Ali Abdalla, Saori Fujiwara, Tatsuro Yamamoto, Hirotaka Iwase, Mitsuyoshi Nakao, Noriko Saitoh
Published Online: Aug 03 2016
DOI:10.1002/wrna.1384

Abstract Full article on Wiley Online Library:   HTML | PDF
Identifying fusion transcripts using next generation sequencing

Advanced Review
Shailesh Kumar, Sundus Khalid Razzaq, Angie Duy Vo, Mamta Gautam, Hui Li
Published Online: Aug 02 2016
DOI:10.1002/wrna.1382

Abstract Full article on Wiley Online Library:   HTML | PDF
Hallmarks of cancer and AU‐rich elements

Advanced Review
Khalid S. A. Khabar
Published Online: Jun 01 2016
DOI:10.1002/wrna.1368

Abstract Full article on Wiley Online Library:   HTML | PDF
Exosome‐mediated small RNA delivery for gene therapy

Advanced Review
Yu Zhou, Geyu Zhou, Chenfei Tian, Waner Jiang, Ling Jin, Chenyu Zhang, Xi Chen
Published Online: May 16 2016
DOI:10.1002/wrna.1363

Abstract Full article on Wiley Online Library:   HTML | PDF
RNA‐binding proteins in eye development and disease: implication of conserved RNA granule components

Advanced Review
Soma Dash, Archana D. Siddam, Carrie E. Barnum, Sarath Chandra Janga, Salil A. Lachke
Published Online: May 01 2016
DOI:10.1002/wrna.1355

Abstract Full article on Wiley Online Library:   HTML | PDF
Dysregulated axonal RNA translation in amyotrophic lateral sclerosis

Advanced Review
Kyota Yasuda, Stavroula Mili
Published Online: Mar 31 2016
DOI:10.1002/wrna.1352

Abstract Full article on Wiley Online Library:   HTML | PDF
Emerging functions of the Quaking RNA‐binding proteins and link to human diseases

Advanced Review
Lama Darbelli, Stéphane Richard
Published Online: Mar 14 2016
DOI:10.1002/wrna.1344

Abstract Full article on Wiley Online Library:   HTML | PDF
siRNA and RNAi optimization

Advanced Review
Adele Alagia, Ramon Eritja
Published Online: Feb 02 2016
DOI:10.1002/wrna.1337

Abstract Full article on Wiley Online Library:   HTML | PDF
Matrin3: connecting gene expression with the nuclear matrix

Advanced Review
Christopher W.J. Smith, Jernej Ule, Jan Attig, Miguel B. Coelho
Published Online: Jan 26 2016
DOI:10.1002/wrna.1336

Abstract Full article on Wiley Online Library:   HTML | PDF
Diverse roles of the nucleic acid‐binding protein KHSRP in cell differentiation and disease

Advanced Review
Roberto Gherzi, Nora Perrone‐Bizzozero, Martina Rossi, Franco Gorlero, Margherita Puppo, Domenico Bordo, Paola Briata
Published Online: Dec 27 2015
DOI:10.1002/wrna.1327

Abstract Full article on Wiley Online Library:   HTML | PDF
lncRNAs regulate the innate immune response to viral infection

Advanced Review
Jing Ouyang, Jiayue Hu, Ji‐Long Chen
Published Online: Dec 15 2015
DOI:10.1002/wrna.1321

Abstract Full article on Wiley Online Library:   HTML | PDF
Can circulating miRNAs live up to the promise of being minimal invasive biomarkers in clinical settings?

Focus Article
Eckart Meese, Andreas Keller
Published Online: Dec 15 2015
DOI:10.1002/wrna.1320

Abstract Full article on Wiley Online Library:   HTML | PDF
Satellite RNA pathogens of plants: impacts and origins—an RNA silencing perspective

Advanced Review
Ming‐Bo Wang, Neil A. Smith
Published Online: Oct 20 2015
DOI:10.1002/wrna.1311

Abstract Full article on Wiley Online Library:   HTML | PDF
Roles of microRNAs and long‐noncoding RNAs in human immunodeficiency virus replication

Advanced Review
Andrew P. Rice
Published Online: Sep 22 2015
DOI:10.1002/wrna.1308

Abstract Full article on Wiley Online Library:   HTML | PDF
‘Micro‐managers’ of hepatic lipid metabolism and NAFLD

Advanced Review
Wei Liu, Hongchao Cao, Jun Yan, Ruimin Huang, Hao Ying
Published Online: Jul 21 2015
DOI:10.1002/wrna.1295

Abstract Full article on Wiley Online Library:   HTML | PDF
The potential of the riboSNitch in personalized medicine

Advanced Review
Amanda C. Solem, Matthew Halvorsen, Silvia B. V. Ramos, Alain Laederach
Published Online: Jun 26 2015
DOI:10.1002/wrna.1291

Abstract Full article on Wiley Online Library:   HTML | PDF
Recombinant messenger RNA technology and its application in cancer immunotherapy, transcript replacement therapies, pluripotent stem cell induction, and beyond

Advanced Review
Britta Vallazza, Sebastian Petri, Marco A. Poleganov, Florian Eberle, Andreas N. Kuhn, Ugur Sahin
Published Online: Jun 09 2015
DOI:10.1002/wrna.1288

Abstract Full article on Wiley Online Library:   HTML | PDF
Modulation of alternative splicing by anticancer drugs

Advanced Review
Sayeed Ur Rehman, Mohammed Amir Husain, Tarique Sarwar, Hassan Mubarak Ishqi, Mohammad Tabish
Published Online: Apr 24 2015
DOI:10.1002/wrna.1283

Abstract Full article on Wiley Online Library:   HTML | PDF
Cutting, dicing, healing and sealing: the molecular surgery of tRNA

Advanced Review
Raphael R.S. Lopes, Alan C. Kessler, Carla Polycarpo, Juan D. Alfonzo
Published Online: Mar 06 2015
DOI:10.1002/wrna.1279

Abstract Full article on Wiley Online Library:   HTML | PDF
Functional roles of alternative splicing factors in human disease

Advanced Review
Russ P. Carstens, Benjamin Cieply
Published Online: Jan 28 2015
DOI:10.1002/wrna.1276

Abstract Full article on Wiley Online Library:   HTML | PDF
Small RNAs with big implications: new insights into H/ACA snoRNA function and their role in human disease

Advanced Review
Mary McMahon, Adrian Contreras, Davide Ruggero
Published Online: Oct 31 2014
DOI:10.1002/wrna.1266

Abstract Full article on Wiley Online Library:   HTML | PDF
Understanding the potential of hepatitis C virus internal ribosome entry site domains to modulate translation initiation via their structure and function

Advanced Review
Martin Pospisek, Vaclav Vopalensky, Anas Khawaja
Published Online: Oct 28 2014
DOI:10.1002/wrna.1268

Abstract Full article on Wiley Online Library:   HTML | PDF
An overview of pre‐ribosomal RNA processing in eukaryotes

Overview
Pierre‐Emmanuel Gleizes, Anirban Chakraborty, Marie‐Françoise O'Donohue, Célia Plisson‐Chastang, Anthony K. Henras
Published Online: Oct 27 2014
DOI:10.1002/wrna.1269

Abstract Full article on Wiley Online Library:   HTML | PDF
CLP1 as a novel player in linking tRNA splicing to neurodegenerative disorders

Advanced Review
Javier Martinez, Josef M. Penninger, Toshikatsu Hanada, Stefan Weitzer
Published Online: Aug 20 2014
DOI:10.1002/wrna.1255

Abstract Full article on Wiley Online Library:   HTML | PDF
microRNAs: role in leukemia and their computational perspective

Advanced Review
Rama Kant Singh, Navneet Kumar Yadav, Poonam Singh, Ankur Omer
Published Online: Aug 15 2014
DOI:10.1002/wrna.1256

Abstract Full article on Wiley Online Library:   HTML | PDF
Not miR‐ly micromanagers: the functions and regulatory networks of microRNAs in mammalian skin

Advanced Review
Rui Yi, Jaimee E Hoefert, Kent Riemondy
Published Online: Jul 09 2014
DOI:10.1002/wrna.1250

Abstract Full article on Wiley Online Library:   HTML | PDF
The role of microRNA in resistance to breast cancer therapy

Advanced Review
Neil M. Robertson, Mehmet V. Yigit
Published Online: Jul 08 2014
DOI:10.1002/wrna.1248

Abstract Full article on Wiley Online Library:   HTML | PDF
Small noncoding RNAs and male infertility

Overview
Lan‐Tao Gou, Peng Dai, Mo‐Fang Liu
Published Online: Jul 08 2014
DOI:10.1002/wrna.1252

Abstract Full article on Wiley Online Library:   HTML | PDF
MicroRNA in skeletal muscle development, growth, atrophy, and disease

Advanced Review
Anja Kovanda, Tadeja Režen, Boris Rogelj
Published Online: May 16 2014
DOI:10.1002/wrna.1227

Abstract Full article on Wiley Online Library:   HTML | PDF
MicroRNAs as therapeutic targets in human cancers

Advanced Review
Maitri Y. Shah, George A. Calin
Published Online: Mar 28 2014
DOI:10.1002/wrna.1229

Abstract Full article on Wiley Online Library:   HTML | PDF
Physiological networks and disease functions of RNA‐binding protein AUF1

Advanced Review
Ashleigh E. Moore, Devon M. Chenette, Lauren C. Larkin, Robert J. Schneider
Published Online: Mar 28 2014
DOI:10.1002/wrna.1230

Abstract Full article on Wiley Online Library:   HTML | PDF
Neuronal RNA‐binding proteins in health and disease

Advanced Review
Silvia Carolina Lenzken, Tilmann Achsel, Maria Teresa Carrì, Silvia M.L. Barabino
Published Online: Mar 28 2014
DOI:10.1002/wrna.1231

Abstract Full article on Wiley Online Library:   HTML | PDF
Telomeric noncoding RNA: telomeric repeat‐containing RNA in telomere biology

Advanced Review
Emilio Cusanelli, Pascal Chartrand
Published Online: Feb 12 2014
DOI:10.1002/wrna.1220

Abstract Full article on Wiley Online Library:   HTML | PDF
Battle against RNA oxidation: molecular mechanisms for reducing oxidized RNA to protect cells

Advanced Review
Zhongwei Li, Sulochan Malla, Brian Shin, James M. Li
Published Online: Dec 16 2013
DOI:10.1002/wrna.1214

Abstract Full article on Wiley Online Library:   HTML | PDF
Effects of stress and aging on ribonucleoprotein assembly and function in the germ line

Advanced Review
Jennifer A. Schisa
Published Online: Nov 13 2013
DOI:10.1002/wrna.1204

Abstract Full article on Wiley Online Library:   HTML | PDF
Regulation of genes in the arachidonic acid metabolic pathway by RNA processing and RNA‐mediated mechanisms

Advanced Review
Carol S. Lutz, Ashley L. Cornett
Published Online: Aug 16 2013
DOI:10.1002/wrna.1183

Abstract Full article on Wiley Online Library:   HTML | PDF
Regulation of flavivirus RNA synthesis and capping

Advanced Review
Bejan J. Saeedi, Brian J. Geiss
Published Online: Aug 08 2013
DOI:10.1002/wrna.1191

Abstract Full article on Wiley Online Library:   HTML | PDF
Messenger RNA‐based vaccines: progress, challenges, applications

Focus Article
Thomas Kramps, Jochen Probst
Published Online: Jul 25 2013
DOI:10.1002/wrna.1189

Abstract Full article on Wiley Online Library:   HTML | PDF
miR‐122 Promotion of the hepatitis C virus life cycle: sound in the silence

Advanced Review
Joyce A. Wilson, Adam Huys
Published Online: Jul 23 2013
DOI:10.1002/wrna.1186

Abstract Full article on Wiley Online Library:   HTML | PDF
Aberrant splicing in neurological diseases

Advanced Review
Dairong Feng, Jiuyong Xie
Published Online: Jul 02 2013
DOI:10.1002/wrna.1184

Abstract Full article on Wiley Online Library:   HTML | PDF
U6 RNA biogenesis and disease association

Advanced Review
Seweryn Mroczek, Andrzej Dziembowski
Published Online: Jun 14 2013
DOI:10.1002/wrna.1181

Abstract Full article on Wiley Online Library:   HTML | PDF
The RNase II/RNB family of exoribonucleases: putting the ‘Dis’ in disease

Focus Article
Filipa P. Reis, Vânia Pobre, Inês J. Silva, Michal Malecki, Cecília M. Arraiano
Published Online: Jun 14 2013
DOI:10.1002/wrna.1180

Abstract Full article on Wiley Online Library:   HTML | PDF
Alternative RNA splicing and cancer

Advanced Review
Sali Liu, Chonghui Cheng
Published Online: Jun 13 2013
DOI:10.1002/wrna.1178

Abstract Full article on Wiley Online Library:   HTML | PDF
Posttranscriptional regulation of retroviral gene expression: primary RNA transcripts play three roles as pre‐mRNA, mRNA, and genomic RNA

Advanced Review
Jason LeBlanc, Jason Weil, Karen Beemon
Published Online: Jun 10 2013
DOI:10.1002/wrna.1179

Abstract Full article on Wiley Online Library:   HTML | PDF
Mapping and significance of the mRNA methylome

Advanced Review
Tennille Sibbritt, Hardip R. Patel, Thomas Preiss
Published Online: May 16 2013
DOI:10.1002/wrna.1166

Abstract Full article on Wiley Online Library:   HTML | PDF
Perturbations of RNA helicases in cancer

Advanced Review
Francis Robert, Jerry Pelletier
Published Online: May 08 2013
DOI:10.1002/wrna.1163

Abstract Full article on Wiley Online Library:   HTML | PDF
RNA synthetic mechanisms employed by diverse families of RNA viruses

Advanced Review
Sarah M. McDonald
Published Online: Apr 18 2013
DOI:10.1002/wrna.1164

Abstract Full article on Wiley Online Library:   HTML | PDF
Regulation of stress granules and P‐bodies during RNA virus infection

Advanced Review
Richard E. Lloyd
Published Online: Apr 03 2013
DOI:10.1002/wrna.1162

Abstract Full article on Wiley Online Library:   HTML | PDF
Targeting RNA splicing for disease therapy

Advanced Review
Mallory A. Havens, Dominik M. Duelli, Michelle L. Hastings
Published Online: Mar 19 2013
DOI:10.1002/wrna.1158

Abstract Full article on Wiley Online Library:   HTML | PDF
RNAs of the human chromosome 15q11‐q13 imprinted region

Advanced Review
Stormy J. Chamberlain
Published Online: Dec 03 2012
DOI:10.1002/wrna.1150

Abstract Full article on Wiley Online Library:   HTML | PDF
The curious case of miRNAs in circulation: potential diagnostic biomarkers?

Focus Article
Radha Duttagupta, Keith W. Jones
Published Online: Nov 08 2012
DOI:10.1002/wrna.1149

Abstract Full article on Wiley Online Library:   HTML | PDF
Perspectives on the ARE as it turns 25 years old

Focus Article
Daniel Beisang, Paul R. Bohjanen
Published Online: Jun 25 2012
DOI:10.1002/wrna.1125

Abstract Full article on Wiley Online Library:   HTML | PDF
Potential pitfalls in microRNA profiling

Advanced Review
Pauline Chugh, Dirk P. Dittmer
Published Online: May 07 2012
DOI:10.1002/wrna.1120

Abstract Full article on Wiley Online Library:   HTML | PDF
The 5′ → 3′ exoribonuclease XRN1/Pacman and its functions in cellular processes and development

Advanced Review
Christopher Iain Jones, Maria Vasilyevna Zabolotskaya, Sarah Faith Newbury
Published Online: Mar 01 2012
DOI:10.1002/wrna.1109

Abstract Full article on Wiley Online Library:   HTML | PDF
RNA decay: a novel therapeutic target in bacteria

Focus Article
Tess M. Eidem, Christelle M. Roux, Paul M. Dunman
Published Online: Feb 28 2012
DOI:10.1002/wrna.1110

Abstract Full article on Wiley Online Library:   HTML | PDF
Current advances in Phi29 pRNA biology and its application in drug delivery

Advanced Review
Xin Ye, Maged Hemida, Huifang M. Zhang, Paul Hanson, Qiu Ye, Decheng Yang
Published Online: Feb 23 2012
DOI:10.1002/wrna.1111

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Roles of tRNA in cell wall biosynthesis

Advanced Review
Kiley Dare, Michael Ibba
Published Online: Jan 19 2012
DOI:10.1002/wrna.1108

Abstract Full article on Wiley Online Library:   HTML | PDF
The role of RNA in mammalian prion protein conversion

Advanced Review
Mariana P. B. Gomes, Tuane C. R. G. Vieira, Yraima Cordeiro, Jerson L. Silva
Published Online: Nov 17 2011
DOI:10.1002/wrna.118

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Quality control in tRNA charging

Advanced Review
Hieronim Jakubowski
Published Online: Nov 17 2011
DOI:10.1002/wrna.122

Abstract Full article on Wiley Online Library:   HTML | PDF
Genetic variation of pre‐mRNA alternative splicing in human populations

Focus Article
Zhi‐Xiang Lu, Peng Jiang, Yi Xing
Published Online: Nov 17 2011
DOI:10.1002/wrna.120

Abstract Full article on Wiley Online Library:   HTML | PDF
RNA‐binding proteins in neurodegenerative disease: TDP‐43 and beyond

Advanced Review
Keith A. Hanson, Sang Hwa Kim, Randal S. Tibbetts
Published Online: Oct 25 2011
DOI:10.1002/wrna.111

Abstract Full article on Wiley Online Library:   HTML | PDF
Aging—RNA in development and disease

Advanced Review
Mark R. Cookson
Published Online: Sep 06 2011
DOI:10.1002/wrna.109

Abstract Full article on Wiley Online Library:   HTML | PDF
mRNA export and cancer

Advanced Review
Nadeem Siddiqui, Katherine L. B. Borden
Published Online: Jul 27 2011
DOI:10.1002/wrna.101

Abstract Full article on Wiley Online Library:   HTML | PDF
Regulating iron storage and metabolism with RNA: an overview of posttranscriptional controls of intracellular iron homeostasis

Overview
Hubert Salvail, Eric Massé
Published Online: Jul 25 2011
DOI:10.1002/wrna.102

Abstract Full article on Wiley Online Library:   HTML | PDF
The maze of paramutation: a rough guide to the puzzling epigenetics of paramutation

Advanced Review
Jan Brzeski, Katarzyna Brzeska
Published Online: Jul 08 2011
DOI:10.1002/wrna.97

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Suppression of nonsense mutations as a therapeutic approach to treat genetic diseases

Advanced Review
Kim M. Keeling, David M. Bedwell
Published Online: Jul 06 2011
DOI:10.1002/wrna.95

Abstract Full article on Wiley Online Library:   HTML | PDF
Biogenesis of spliceosomal small nuclear ribonucleoproteins

Advanced Review
Utz Fischer, Clemens Englbrecht, Ashwin Chari
Published Online: Apr 25 2011
DOI:10.1002/wrna.87

Abstract Full article on Wiley Online Library:   HTML | PDF
Eukaryotic 5S rRNA biogenesis

Advanced Review
Martin Ciganda, Noreen Williams
Published Online: Feb 25 2011
DOI:10.1002/wrna.74

Abstract Full article on Wiley Online Library:   HTML | PDF
SMN in spinal muscular atrophy and snRNP biogenesis

Advanced Review
Tristan H. Coady, Christian L. Lorson
Published Online: Feb 17 2011
DOI:10.1002/wrna.76

Abstract Full article on Wiley Online Library:   HTML | PDF
The roles of TTP and BRF proteins in regulated mRNA decay

Advanced Review
Sandhya Sanduja, Fernando F. Blanco, Dan A. Dixon
Published Online: Dec 16 2010
DOI:10.1002/wrna.28

Abstract Full article on Wiley Online Library:   HTML | PDF
HuR's role in gemcitabine efficacy: an exception or opportunity?

Advanced Review
Jonathan R. Brody, Gregory E. Gonye
Published Online: Nov 30 2010
DOI:10.1002/wrna.62

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MicroRNAs in cardiac hypertrophy: angels or devils

Advanced Review
Su‐Ling Ding, Lu‐Yu Zhou, Pei‐Feng Li
Published Online: Nov 22 2010
DOI:10.1002/wrna.61

Abstract Full article on Wiley Online Library:   HTML | PDF
RNA diagnostics: real‐time RT‐PCR strategies and promising novel target RNAs

Focus Article
Günter Mayer, Jens Müller, Christina E. Lünse
Published Online: Sep 27 2010
DOI:10.1002/wrna.46

Abstract Full article on Wiley Online Library:   HTML | PDF
The nucleolus: structure/function relationship in RNA metabolism

Advanced Review
Danièle Hernandez‐Verdun, Pascal Roussel, Marc Thiry, Valentina Sirri, Denis L. J. Lafontaine
Published Online: Sep 22 2010
DOI:10.1002/wrna.39

Abstract Full article on Wiley Online Library:   HTML | PDF
A central role for RNA in the induction and biological activities of type 1 interferons

Advanced Review
Xiao‐Ling Li, Heather J. Ezelle, Teresa Y. Hsi, Bret A. Hassel
Published Online: Aug 24 2010
DOI:10.1002/wrna.32

Abstract Full article on Wiley Online Library:   HTML | PDF
Delivery of RNAi mediators

Focus Article
Lance P. Ford, Masoud M. Toloue
Published Online: Aug 17 2010
DOI:10.1002/wrna.12

Abstract Full article on Wiley Online Library:   HTML | PDF
From cradle to grave: RNA biology in malaria parasites

Advanced Review
Katie R. Hughes, Nisha Philip, G. Lucas Starnes, Sonya Taylor, Andrew P. Waters
Published Online: Aug 02 2010
DOI:10.1002/wrna.30

Abstract Full article on Wiley Online Library:   HTML | PDF
Mitochondrial tRNA mutations and disease

Advanced Review
John W. Yarham, Joanna L. Elson, Emma L. Blakely, Robert McFarland, Robert W. Taylor
Published Online: Jul 21 2010
DOI:10.1002/wrna.27

Abstract Full article on Wiley Online Library:   HTML | PDF
Viroids: self‐replicating, mobile, and fast‐evolving noncoding regulatory RNAs

Advanced Review
Biao Ding
Published Online: Jun 23 2010
DOI:10.1002/wrna.22

Abstract Full article on Wiley Online Library:   HTML | PDF
Repeat expansion diseases: when a good RNA turns bad

Advanced Review
Alexa M. Dickson, Carol J. Wilusz
Published Online: May 25 2010
DOI:10.1002/wrna.18

Abstract Full article on Wiley Online Library:   HTML | PDF
Inflammation: cytokines and RNA‐based regulation

Advanced Review
Deborah J. Stumpo, Wi S. Lai, Perry J. Blackshear
Published Online: May 06 2010
DOI:10.1002/wrna.1

Abstract Full article on Wiley Online Library:   HTML | PDF
Biogenesis and function of endogenous and exogenous siRNAs

Advanced Review
Nicholas M. Snead, John J. Rossi
Published Online: May 06 2010
DOI:10.1002/wrna.14

Abstract Full article on Wiley Online Library:   HTML | PDF
Viruses and the cellular RNA decay machinery

Advanced Review
Marta Maria Gaglia, Britt A. Glaunsinger
Published Online: May 06 2010
DOI:10.1002/wrna.3

Abstract Full article on Wiley Online Library:   HTML | PDF
Posttranscriptional regulation of cancer traits by HuR

Advanced Review
Kotb Abdelmohsen, Myriam Gorospe
Published Online: May 06 2010
DOI:10.1002/wrna.4

Abstract Full article on Wiley Online Library:   HTML | PDF
Posttranscriptional control and the role of RNA‐binding proteins in gene regulation in trypanosomatid protozoan parasites

Advanced Review
Sandra M. Fernández‐Moya, Antonio M. Estévez
Published Online: May 06 2010
DOI:10.1002/wrna.6

Abstract Full article on Wiley Online Library:   HTML | PDF
Plant viruses versus RNAi: Simple pathogens reveal complex insights on plant antimicrobial defense

Advanced Review
Feng Qu
Published Online: May 06 2010
DOI:10.1002/wrna.7

Abstract Full article on Wiley Online Library:   HTML | PDF
RNase MRP and disease

Advanced Review
Sandy Mattijssen, Tim J. M. Welting, Ger J. M. Pruijn
Published Online: May 06 2010
DOI:10.1002/wrna.9

Abstract Full article on Wiley Online Library:   HTML | PDF
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