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WIREs Dev Biol

Gene Networks and Genomics

Set2 mediated H3 lysine 36 methylation: regulation of transcription elongation and implications in organismal development

Advanced Review
Swaminathan Venkatesh, Jerry L. Workman
Published Online: Feb 01 2013
DOI:10.1002/wdev.109

Abstract Full article on Wiley Online Library:   HTML | PDF
The evolution of vision

Advanced Review
Walter J. Gehring
Published Online: Dec 21 2012
DOI:10.1002/wdev.96

Abstract Full article on Wiley Online Library:   HTML | PDF
The Caenorhabditis elegans intestine

Advanced Review
James D. McGhee
Published Online: Oct 09 2012
DOI:10.1002/wdev.93

Abstract Full article on Wiley Online Library:   HTML | PDF
Evolution of homeobox genes

Advanced Review
Peter W. H. Holland
Published Online: Sep 10 2012
DOI:10.1002/wdev.78

Abstract Full article on Wiley Online Library:   HTML | PDF
The molecular basis of human congenital limb malformations

Advanced Review
Aimée Zuniga, Rolf Zeller, Simone Probst
Published Online: Apr 26 2012
DOI:10.1002/wdev.59

Abstract Full article on Wiley Online Library:   HTML | PDF
Mathematical models of morphogen gradients and their effects on gene expression

Advanced Review
Stanislav Y. Shvartsman, Ruth E. Baker
Published Online: Apr 12 2012
DOI:10.1002/wdev.55

Abstract Full article on Wiley Online Library:   HTML | PDF
Morphogenesis in sea urchin embryos: linking cellular events to gene regulatory network states

Advanced Review
Deirdre C. Lyons, Stacy L. Kaltenbach, David R. McClay
Published Online: Dec 27 2011
DOI:10.1002/wdev.18

Abstract Full article on Wiley Online Library:   HTML | PDF
Perspectives on the RNA polymerase II core promoter

Advanced Review
James T. Kadonaga
Published Online: Dec 06 2011
DOI:10.1002/wdev.21

Abstract Full article on Wiley Online Library:   HTML | PDF
Neural crest specification: tissues, signals, and transcription factors

Advanced Review
C.D. Rogers, C.S. Jayasena, S. Nie, M.E. Bronner
Published Online: Nov 17 2011
DOI:10.1002/wdev.8

Abstract Full article on Wiley Online Library:   HTML | PDF

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In the Spotlight

Philip Benfey

Philip Benfey

Is intrigued by one of the key questions in developmental biology: how cells acquire their identities. This is an important question in human development, where stem cells divide and differentiate into skin, muscle, fat etc. It is equally central to plant development, where most organs and cells are formed from stem cell populations known as meristems. The Benfey lab addresses this question using a combination of genetics, molecular biology, and genomics to identify and characterize the genes that regulate formation of the root in the plant model system, Arabidopsis thaliana. The choice of the root as a model was based on the simplicity of its organization and its stereotyped developmental program.

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