Hofstadter, DR. Metamagical Themas: Questing for the Essence of Mind and Pattern. New York: Basic Books; 1985.
West‐Eberhard, MJ. Developmental Plasticity and Evolution. Oxford; New York: Oxford University Press; 2003.
Newman, SA, Bhat, R, Mezentseva, NV. Cell state switching factors and dynamical patterning modules: complementary mediators of plasticity in development and evolution. J Biosci 2009, 34:553–572.
Bissell, MJ, Hall, HG, Parry, G. How does the extracellular matrix direct gene expression? J Theor Biol 1982, 99:31–68.
Bissell, MJ, Hall, HG. %22Form and function in the mammary gland: the role of extracellular matrix%22. In: Nevell, MC, Neville, CWD, eds. The Mammary Gland: Development, Regulation and Function. New York: Plenum Publishing Corp; 1987, 97–146.
Davidson, EH. The Regulatory Genome: Gene Regulatory Networks in Development and Evolution (New edn). Oxford: Academic Press; 2005.
Wilmut, I, Schnieke, AE, McWhir, J, Kind, AJ, Campbell, KH. Viable offspring derived from fetal and adult mammalian cells. Nature 1997, 385:810–813.
Mezentseva, NV, Kumaratilake, JS, Newman, SA. The brown adipocyte differentiation pathway in birds: an evolutionary road not taken. BMC Biol 2008, 6:17.
Schlichting, CD, Smith, H. Phenotypic plasticity: linking molecular mechanisms with evolutionary outcomes. Evol Ecol 2002, 16:189–211.
Vedel, V, Chipman, AD, Akam, M, Arthur, W. Temperature‐dependent plasticity of segment number in an arthropod species: the centipede Strigamia maritima. Evol Dev 2008, 10:487–492.
Moczek, AP. Integrating micro‐ and macroevolution of development through the study of horned beetles. Heredity 2006, 97:168–178.
Weisser, WW, Braendle, C, Minoretti, N. Predator‐induced morphological shift in the pea aphid. Proc R Soc B Biol Sci 1999, 266:1175–1181.
Sturkie, PD. Suppression of polydactyly in the domestic fowl by low temperature. J Exp Zool 1943, 93:325–346.
Neufeld, CJ, Palmer, AR. Precisely proportioned: intertidal barnacles alter penis form to suit coastal wave action. Proceedings of the Royal Society B‐Biological Sciences 2008, 275:1081–1087.
Brakefield, PM, Kesbeke, F, Koch, PB. The regulation of phenotypic plasticity of eyespots in the butterfly Bicyclus anynana. Am Nat 1998, 152:853–860.
Miyakawa, H, Imai, M, Sugimoto, N, Ishikawa, Y, Ishikawa, A, Ishigaki, H, Okada, Y, Miyazaki, S, Koshikawa, S, Cornette, R, et al. Gene up‐regulation in response to predator kairomones in the water flea, Daphnia pulex. BMC Dev Biol 2010, 10:45.
Lamarck, JB. Philosophie zoologique, ou, Exposition des considérations relatives à l`histoire naturelle des animaux, Paris; 1809.
Newman, SA, Forgacs, G, Muller, GB. Before programs: the physical origination of multicellular forms. Int J Dev Biol 2006, 50:289–299.
de Gennes, PG. Soft matter. Science 1992, 256:495–497.
Mikhailov, AS. Foundations of Synergetics; Berlin; New York: Springer; 1990.
Suel, GM, Garcia‐Ojalvo, J, Liberman, LM, Elowitz, MB. An excitable gene regulatory circuit induces transient cellular differentiation. Nature 2006, 440:545–550.
Gasch, AP, Spellman, PT, Kao, CM, Carmel‐Harel, O, Eisen, MB, Storz, G, Botstein, D, Brown, PO. Genomic expression programs in the response of yeast cells to environmental changes. Mol Biol Cell 2000, 11:4241–4257.
Balazsi, G, van Oudenaarden, A, Collins, JJ. Cellular decision making and biological noise: from microbes to mammals. Cell 2011, 144:910–925.
Boettiger, AN, Levine, M. Synchronous and stochastic patterns of gene activation in the Drosophila embryo. Science 2009, 325:471–473.
Gregor, T, Tank, DW, Wieschaus, EF, Bialek, W. Probing the limits to positional information. Cell 2007, 130:153–164.
Wernet, MF, Mazzoni, EO, Celik, A, Duncan, DM, Duncan, I, Desplan, C. Stochastic spineless expression creates the retinal mosaic for colour vision. Nature 2006, 440:174–180.
Karp, X, Greenwald, I. Post‐transcriptional regulation of the E/Daughterless ortholog HLH‐2, negative feedback, and birth order bias during the AC/VU decision in C. elegans. Genes Dev 2003, 17:3100–3111.
Johnston, RJ Jr, Desplan, C. Stochastic mechanisms of cell fate specification that yield random or robust outcomes. Annu Rev Cell Dev Biol 2010, 26:689–719.
Kirschner, M, Gerhart, J, Mitchison, T. Molecular “vitalism”. Cell 2000, 100:79–88.
Driever, W, Nusslein‐Volhard, C. A gradient of bicoid protein in Drosophila embryos. Cell 1988, 54:83–93.
Jung, J, Zheng, M, Goldfarb, M, Zaret, KS. Initiation of mammalian liver development from endoderm by fibroblast growth factors. Science 1999, 284:1998–2003.
Lewis, WH. Transplantation of the lips of the blastopore in Rana palustris. Am J Anat 1907, 7:137–143.
Spemann, H, Mangold, H. The induction of embryonic predispositions by implantation of organizers foreign to the species. Arch Mikroskopis Anat Entwicklungsmech 1924, 100:599–638.
Lewis, WH. Experimental studies on the development of the eye in Amphibia I on the origin of the lens Rana palustras. Am J Anat 1904, 3:505–536.
Slack, JMW. From Egg to Embryo: Determinative Events in Early Development. Cambridge: Cambridge University Press; 1983.
Forgács, G, Newman, S. Biological Physics of the Developing Embryo. Cambridge; New York: Cambridge University Press; 2005.
Hens, JR, Wysolmerski, JJ. Key stages of mammary gland development: molecular mechanisms involved in the formation of the embryonic mammary gland. Breast Cancer Res 2005, 7:220–224.
Coleman, S, Silberstein, GB, Daniel, CW. Ductal morphogenesis in the mouse mammary gland: evidence supporting a role for epidermal growth factor. Dev Biol 1988, 127:304–315.
Kenney, NJ, Bowman, A, Korach, KS, Barrett, JC, Salomon, DS. Effect of exogenous epidermal‐like growth factors on mammary gland development and differentiation in the estrogen receptor‐α knockout (ERKO) mouse. Breast Cancer Res Treat 2003, 79:161–173.
Sternlicht, MD, Sunnarborg, SW, Kouros‐Mehr, H, Yu, Y, Lee, DC, Werb, Z. Mammary ductal morphogenesis requires paracrine activation of stromal EGFR via ADAM17‐dependent shedding of epithelial amphiregulin. Development 2005, 132:3923–3933.
Fata, JE, Mori, H, Ewald, AJ, Zhang, H, Yao, E, Werb, Z, Bissell, MJ. The MAPK(ERK‐1,2) pathway integrates distinct and antagonistic signals from TGFα and FGF7 in morphogenesis of mouse mammary epithelium. Dev Biol 2007, 306:193–207.
Ewan, KB, Shyamala, G, Ravani, SA, Tang, Y, Akhurst, R, Wakefield, L, Barcellos‐Hoff, MH. Latent transforming growth factor‐β activation in mammary gland: regulation by ovarian hormones affects ductal and alveolar proliferation. Am J Pathol 2002, 160:2081–2093.
Daniel, CW, Robinson, S, Silberstein, GB. The role of TGF‐β in patterning and growth of the mammary ductal tree. J Mammary Gland Biol Neoplasia 1996, 1:331–341.
Nelson, CM, Vanduijn, MM, Inman, JL, Fletcher, DA, Bissell, MJ. Tissue geometry determines sites of mammary branching morphogenesis in organotypic cultures. Science 2006, 314:298–300.
Pavlovich, AL, Boghaert, E, Nelson, CM. Mammary branch initiation and extension are inhibited by separate pathways downstream of TGFβ in culture. Exp Cell Res 2011, 317:1872–1884.
Hayes, S. Shaped to split. Nat Cell Biol 2006, 8:1325.
Barcellos‐Hoff, MH, Aggeler, J, Ram, TG, Bissell, MJ. Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane. Development 1989, 105:223–235.
Ervasti, JM, Campbell, KP. A role for the dystrophin‐glycoprotein complex as a transmembrane linker between laminin and actin. J Cell Biol 1993, 122:809–823.
Grobstein, C. %22xxx%22. In: Rudnik, D, ed. Aspects of Synthesis and Order in Growth. Princeton, NJ: Princeton University Press; 1955, 233–256.
Hauschka, SD, Konigsberg, IR. The influence of collagen on the development of muscle clones. Proc Natl Acad Sci U S A 1966, 55:119–126.
Meier, S, Hay, ED. Control of corneal differentiation by extracellular materials. Collagen as a promoter and stabilizer of epithelial stroma production. Dev Biol 1974, 38:249–270.
Keely, PJ, Wu, JE, Santoro, SA. The spatial and temporal expression of the α 2 β 1 integrin and its ligands, collagen I, collagen IV, and laminin, suggest important roles in mouse mammary morphogenesis. Differentiation 1995, 59:1–13.
Brownfield, DG, Venugopalan, G, Lo, A, Mori, H, Tanner, K, Fletcher, DA, Bissell, MJ. Patterned collagen fibers orient branching mammary epithelium through distinct signaling modules. Curr Biol 2013, xx:xx–xx.
Silberstein, GB, Daniel, CW. Glycosaminoglycans in the basal lamina and extracellular matrix of the developing mouse mammary duct. Dev Biol 1982, 90:215–222.
Lochter, A, Bissell, MJ. Involvement of extracellular matrix constituents in breast cancer. Semin Cancer Biol 1995, 6:165–173.
Menko, AS, Kreidberg, JA, Ryan, TT, Van Bockstaele, E, Kukuruzinska, MA. Loss of α3β1 integrin function results in an altered differentiation program in the mouse submandibular gland. Dev Dyn 2001, 220:337–349.
Kreidberg, JA, Donovan, MJ, Goldstein, SL, Rennke, H, Shepherd, K, Jones, RC, Jaenisch, R. α 3 β 1 integrin has a crucial role in kidney and lung organogenesis. Development 1996, 122:3537–3547.
Chen, J, Diacovo, TG, Grenache, DG, Santoro, SA, Zutter, MM. The α(2) integrin subunit‐deficient mouse: a multifaceted phenotype including defects of branching morphogenesis and hemostasis. Am J Pathol 2002, 161:337–344.
Klinowska, TC, Soriano, JV, Edwards, GM, Oliver, JM, Valentijn, AJ, Montesano, R, Streuli, CH. Laminin and β1 integrins are crucial for normal mammary gland development in the mouse. Dev Biol 1999, 215:13–32.
Mori, H, Lo, AT, Inman, JL, Alcaraz, J, Ghajar, CM, Mott, JD, Nelson, CM, Chen, CS, Zhang, H, Bascom, JL, et al. Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin β1. Development 2013, 140:343–352.
Wiseman, BS, Sternlicht, MD, Lund, LR, Alexander, CM, Mott, J, Bissell, MJ, Soloway, P, Itohara, S, Werb, Z. Site‐specific inductive and inhibitory activities of MMP‐2 and MMP‐3 orchestrate mammary gland branching morphogenesis. J Cell Biol 2003, 162:1123–1133.
Alcaraz, J, Mori, H, Ghajar, CM, Brownfield, D, Galgoczy, R, Bissell, MJ. Collective epithelial cell invasion overcomes mechanical barriers of collagenous extracellular matrix by a narrow tube‐like geometry and MMP14‐dependent local softening. Integr Biol 2011, 3:1153–1166.
Bronner‐Fraser, M. Mechanisms of neural crest cell migration. Bioessays 1993, 15:221–230.
Spencer, VA, Costes, S, Inman, JL, Xu, R, Chen, J, Hendzel, MJ, Bissell, MJ. Depletion of nuclear actin is a key mediator of quiescence in epithelial cells. J Cell Sci 2011, 124:123–132.
Gierer, A. Biological features and physical concepts of pattern formation exemplified by hydra. Curr Top Dev Biol 1977, 11:17–59.
Hynes, RO. The evolution of metazoan extracellular matrix. J Cell Biol 2012, 196:671–679.
Gould, SJ. Wonderful Life: The Burgess Shale and Nature of History. 1st ed. New York: W.W. Norton; 1989.
Louvi, A, Artavanis‐Tsakonas, S. Notch signalling in vertebrate neural development. Nat Rev Neurosci 2006, 7:93–102.
Irvine, KD. Fringe, Notch, and making developmental boundaries. Curr Opin Genet Dev 1999, 9:434–441.
Pasquale, EB, Deerinck, TJ, Singer, SJ, Ellisman, MH. Cek5: a membrane receptor‐type tyrosine kinase, is in neurons of the embryonic and postnatal avian brain. J Neurosci 1992, 12:3956–3967.
Ashton, RS, Conway, A, Pangarkar, C, Bergen, J, Lim, KI, Shah, P, Bissell, M, Schaffer, DV. Astrocytes regulate adult hippocampal neurogenesis through ephrin‐B signaling. Nat Neurosci 2012, 15:1399–1406.
Durbin, L, Brennan, C, Shiomi, K, Cooke, J, Barrios, A, Shanmugalingam, S, Guthrie, B, Lindberg, R, Holder, N. Eph signaling is required for segmentation and differentiation of the somites. Genes Dev 1998, 12:3096–3109.
Gerety, SS, Wang, HU, Chen, ZF, Anderson, DJ. Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin‐B2 in cardiovascular development. Mol Cell 1999, 4:403–414.
Kouros‐Mehr, H, Werb, Z. Candidate regulators of mammary branching morphogenesis identified by genome‐wide transcript analysis. Dev Dyn 2006, 235:3404–3412.
Vaught, D, Chen, J, Brantley‐Sieders, DM. Regulation of mammary gland branching morphogenesis by EphA2 receptor tyrosine kinase. Mol Biol Cell 2009, 20:2572–2581.
Hubbard, GD. Drumlinoids of the Catatonk folio. Bull Am Geogr Soc N Y 1906, 38:355–365.
Stedman, TL. Twentieth Century Practice: An International Encyclopedia of Modern Medical Science by Leading Authorities of Europe and America. New York: W. Wood and Company; 1895.
Daniel, CW, Deome, KB. Growth of mouse mammary glands in vivo after monolayer culture. Science 1965, 149:634–636.
Boulanger, CA, Mack, DL, Booth, BW, Smith, GH. Interaction with the mammary microenvironment redirects spermatogenic cell fate in vivo. Proc Natl Acad Sci U S A 2007, 104:3871–3876.
Booth, BW, Mack, DL, Androutsellis‐Theotokis, A, McKay, RD, Boulanger, CA, Smith, GH. The mammary microenvironment alters the differentiation repertoire of neural stem cells. Proc Natl Acad Sci U S A 2008, 105:14891–14896.
Petersen, OW, Ronnov‐Jessen, L, Howlett, AR, Bissell, MJ. Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells. Proc Natl Acad Sci U S A 1992, 89:9064–9068.
Boudreau, N, Sympson, CJ, Werb, Z, Bissell, MJ. Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix. Science 1995, 267:891–893.
Michalopoulos, G, Pitot, HC. Primary culture of parenchymal liver cells on collagen membranes. Morphological and biochemical observations. Exp Cell Res 1975, 94:70–78.
Emerman, JT, Pitelka, DR. Maintenance and induction of morphological differentiation in dissociated mammary epithelium on floating collagen membranes. In Vitro 1977, 13:316–328.
Bissell, MJ. The differentiated state of normal and malignant cells or how to define a “normal” cell in culture. Int Rev Cytol 1981, 70:27–100.
Lee, EY, Parry, G, Bissell, MJ. Modulation of secreted proteins of mouse mammary epithelial cells by the collagenous substrata. J Cell Biol 1984, 98:146–155.
Streuli, CH, Bissell, MJ. Expression of extracellular matrix components is regulated by substratum. J Cell Biol 1990, 110:1405–1415.
Alcaraz, J, Xu, R, Mori, H, Nelson, CM, Mroue, R, Spencer, VA, Brownfield, D, Radisky, DC, Bustamante, C, Bissell, MJ. Laminin and biomimetic extracellular elasticity enhance functional differentiation in mammary epithelia. EMBO J 2008, 27:2829–2838.
Streuli, CH, Bailey, N, Bissell, MJ. Control of mammary epithelial differentiation: basement membrane induces tissue‐specific gene expression in the absence of cell‐cell interaction and morphological polarity. J Cell Biol 1991, 115:1383–1395.
Chen, LH, Bissell, MJ. A novel regulatory mechanism for whey acidic protein gene expression. Cell Regul 1989, 1:45–54.
Lin, CQ, Bissell, MJ. Multi‐faceted regulation of cell differentiation by extracellular matrix. FASEB J 1993, 7:737–743.
Fu, HL, Moss, J, Shore, I, Slade, MJ, Coombes, RC. Ultrastructural localization of laminin and type IV collagen in normal human breast. Ultrastruct Pathol 2002, 26:77–80.
Streuli, CH, Schmidhauser, C, Bailey, N, Yurchenco, P, Skubitz, AP, Roskelley, C, Bissell, MJ. Laminin mediates tissue‐specific gene expression in mammary epithelia. J Cell Biol 1995, 129:591–603.
Gudjonsson, T, Ronnov‐Jessen, L, Villadsen, R, Rank, F, Bissell, MJ, Petersen, OW. Normal and tumor‐derived myoepithelial cells differ in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition. J Cell Sci 2002, 115:39–50.
Dickinson, DJ, Nelson, WJ, Weis, WI. A polarized epithelium organized by β‐ and α‐catenin predates cadherin and metazoan origins. Science 2011, 331:1336–1339.
Rizki, A, Weaver, VM, Lee, SY, Rozenberg, GI, Chin, K, Myers, CA, Bascom, JL, Mott, JD, Semeiks, JR, Grate, LR, et al. A human breast cell model of preinvasive to invasive transition. Cancer Res 2008, 68:1378–1387.
Plachot, C, Chaboub, LS, Adissu, HA, Wang, L, Urazaev, A, Sturgis, J, Asem, EK, Lelievre, SA. Factors necessary to produce basoapical polarity in human glandular epithelium formed in conventional and high‐throughput three‐dimensional culture: example of the breast epithelium. BMC Biol 2009, 7:77.
Underwood, JM, Imbalzano, KM, Weaver, VM, Fischer, AH, Imbalzano, AN, Nickerson, JA. The ultrastructure of MCF‐10A acini. J Cell Physiol 2006, 208:141–148.
Kleinman, HK, McGarvey, ML, Hassell, JR, Star, VL, Cannon, FB, Laurie, GW, Martin, GR. Basement membrane complexes with biological activity. Biochemistry 1986, 25:312–318.
Tanner, K, Mori, H, Mroue, R, Bruni‐Cardoso, A, Bissell, MJ. Coherent angular motion in the establishment of multicellular architecture of glandular tissues. Proc Natl Acad Sci U S A 2012, 109:1973–1978.
Wang, F, Weaver, VM, Petersen, OW, Larabell, CA, Dedhar, S, Briand, P, Lupu, R, Bissell, MJ. Reciprocal interactions between β1‐integrin and epidermal growth factor receptor in three‐dimensional basement membrane breast cultures: a different perspective in epithelial biology. Proc Natl Acad Sci U S A 1998, 95:14821–14826.
Beliveau, A, Mott, JD, Lo, A, Chen, EI, Koller, AA, Yaswen, P, Muschler, J, Bissell, MJ. Raf‐induced MMP9 disrupts tissue architecture of human breast cells in three‐dimensional culture and is necessary for tumor growth in vivo. Genes Dev 2010, 24:2800–2811.
Radisky, DC, Levy, DD, Littlepage, LE, Liu, H, Nelson, CM, Fata, JE, Leake, D, Godden, EL, Albertson, DG, Nieto, MA, et al. Rac1b and reactive oxygen species mediate MMP‐3‐induced EMT and genomic instability. Nature 2005, 436:123–127.
Sternlicht, MD, Lochter, A, Sympson, CJ, Huey, B, Rougier, JP, Gray, JW, Pinkel, D, Bissell, MJ, Werb, Z. The stromal proteinase MMP3/stromelysin‐1 promotes mammary carcinogenesis. Cell 1999, 98:137–146.
Weaver, VM, Petersen, OW, Wang, F, Larabell, CA, Briand, P, Damsky, C, Bissell, MJ. Reversion of the malignant phenotype of human breast cells in three‐dimensional culture and in vivo by integrin blocking antibodies. J Cell Biol 1997, 137:231–245.
Haigo, SL, Bilder, D. Global tissue revolutions in a morphogenetic movement controlling elongation. Science 2011, 331:1071–1074.
Bissell, MJ, Kenny, PA, Radisky, DC. Microenvironmental regulators of tissue structure and function also regulate tumor induction and progression: the role of extracellular matrix and its degrading enzymes. Cold Spring Harb Symp Quant Biol 2005, 70:343–356.
Liu, H, Radisky, DC, Wang, F, Bissell, MJ. Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3‐kinase in breast epithelial tumor cells. J Cell Biol 2004, 164:603–612.
Zhang, X, Fournier, MV, Ware, JL, Bissell, MJ, Yacoub, A, Zehner, ZE. Inhibition of vimentin or β1 integrin reverts morphology of prostate tumor cells grown in laminin‐rich extracellular matrix gels and reduces tumor growth in vivo. Mol Cancer Ther 2009, 8:499–508.
Pearson, GW, Hunter, T. PI‐3 kinase activity is necessary for ERK1/2‐induced disruption of mammary epithelial architecture. Breast Cancer Res 2009, 11:R29.
Zelinski, DP, Zantek, ND, Stewart, JC, Irizarry, AR, Kinch, MS. EphA2 overexpression causes tumorigenesis of mammary epithelial cells. Cancer Res 2001, 61:2301–2306.
Suh, HN, Kim, MO, Han, HJ. Laminin‐111 stimulates proliferation of mouse embryonic stem cells through a reduction of gap junctional intercellular communication via RhoA‐mediated Cx43 phosphorylation and dissociation of Cx43/ZO‐1/Drebrin complex. Stem Cells Dev 2012, xx:xx–xx.
Shekhar, MP, Werdell, J, Santner, SJ, Pauley, RJ, Tait, L. Breast stroma plays a dominant regulatory role in breast epithelial growth and differentiation: implications for tumor development and progression. Cancer Res 2001, 61:1320–1326.
Williams, TM, Sotgia, F, Lee, H, Hassan, G, Di Vizio, D, Bonuccelli, G, Capozza, F, Mercier, I, Rui, H, Pestell, RG, et al. Stromal and epithelial caveolin‐1 both confer a protective effect against mammary hyperplasia and tumorigenesis: caveolin‐1 antagonizes cyclin D1 function in mammary epithelial cells. Am J Pathol 2006, 169:1784–1801.
Strogatz, SH. Nonlinear Dynamics and Chaos: With Applications to Physics, Biology, Chemistry, and Engineering 1st pbk. print. edn. Cambridge, MA: Westview Press; 2000.
Haurie, C, Dale, DC, Mackey, MC. Cyclical neutropenia and other periodic hematological disorders: a review of mechanisms and mathematical models. Blood 1998, 92:2629–2640.
Kaneko, K. Characterization of stem cells and cancer cells on the basis of gene expression profile stability, plasticity, and robustness: dynamical systems theory of gene expressions under cell‐cell interaction explains mutational robustness of differentiated cells and suggests how cancer cells emerge. Bioessays 2011, 33:403–413.
Winfree, AT. The Geometry of Biological Time. 2nd ed. New York: Springer; 2001.
Kaneko K, Tsuda, I. Complex Systems: Chaos and Beyond: A Constructive Approach with Applications in Life Sciences. Berlin; New York: Springer; 2001.
Shiraishi, T, Matsuyama, S, Kitano, H. Large‐scale analysis of network bistability for human cancers. PLoS Comput Biol 2010, 6:e1000851.
Gupta, PB, Fillmore, CM, Jiang, G, Shapira, SD, Tao, K, Kuperwasser, C, Lander, ES. Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells. Cell 2011, 146:633–644.
Kim, J, Villadsen, R, Sorlie, T, Fogh, L, Gronlund, SZ, Fridriksdottir, AJ, Kuhn, I, Rank, F, Wielenga, VT, Solvang, H, et al. Tumor initiating but differentiated luminal‐like breast cancer cells are highly invasive in the absence of basal‐like activity. Proc Natl Acad Sci U S A 2012, 109:6124–6129.
Huang, S, Ernberg, I, Kauffman, S. Cancer attractors: a systems view of tumors from a gene network dynamics and developmental perspective. Semin Cell Dev Biol 2009, 20:869–876.
Dolberg, DS, Bissell, MJ. Inability of Rous sarcoma virus to cause sarcomas in the avian embryo. Nature 1984, 309:552–556.
Stoker, AW, Hatier, C, Bissell, MJ. The embryonic environment strongly attenuates v‐src oncogenesis in mesenchymal and epithelial tissues, but not in endothelia. J Cell Biol 1990, 111:217–228.
Le Beyec, J, Xu, R, Lee, SY, Nelson, CM, Rizki, A, Alcaraz, J, Bissell, MJ. Cell shape regulates global histone acetylation in human mammary epithelial cells. Exp Cell Res 2007, 313:3066–3075.
Plachot, C, Lelievre, SA. DNA methylation control of tissue polarity and cellular differentiation in the mammary epithelium. Exp Cell Res 2004, 298:122–132.
Torday, JS, Rehan, VK. Cell‐cell signaling drives the evolution of complex traits: introduction‐lung evo‐devo. Integr Comp Biol 2009, 49:142–154.
Gomez, C, Ozbudak, EM, Wunderlich, J, Baumann, D, Lewis, J, Pourquie, O. Control of segment number in vertebrate embryos. Nature 2008, 454:335–339.
Doyle, JC, Csete, M. Architecture, constraints, and behavior. Proc Natl Acad Sci U S A 2011, 108(Suppl 3):15624–15630.
Radisky, D, Hagios, C, Bissell, MJ. Tumors are unique organs defined by abnormal signaling and context. Semin Cancer Biol 2001, 11:87–95.