Home
This Title All WIREs
WIREs RSS Feed
How to cite this WIREs title:
WIREs RNA
Impact Factor: 4.928

Small noncoding RNAs and male infertility

Full article on Wiley Online Library:   HTML PDF

Can't access this content? Tell your librarian.

Small noncoding RNAs (ncRNAs) are a novel class of gene regulators that modulate gene expression at transcriptional, post‐transcriptional, and epigenetic levels, and they play crucial roles in almost all cellular processes in eukaryotes. Recent studies have indicated that several types of small noncoding RNAs, including microRNAs (miRNAs), endo‐small interference RNAs (endo‐siRNAs), and Piwi‐interacting RNAs (piRNAs), are expressed in the male germline and are required for spermatogenesis in animals. In this review, we summarize the recent knowledge of these small noncoding RNAs in male germ cells and their biological functions and mechanisms of action in animal spermatogenesis. WIREs RNA 2014, 5:733–745. doi: 10.1002/wrna.1252 This article is categorized under: Regulatory RNAs/RNAi/Riboswitches > Regulatory RNAs RNA in Disease and Development > RNA in Disease RNA in Disease and Development > RNA in Development
Function of small RNAs in mouse spermatogenesis. A schematic drawing of the expression and function of microRNAs, pre‐pachytene piRNAs, and pachytene piRNAs during mouse spermatogenesis.
[ Normal View | Magnified View ]

Related Articles

Epigenetics: An Interdisciplinary View

Browse by Topic

Regulatory RNAs/RNAi/Riboswitches > Regulatory RNAs
RNA in Disease and Development > RNA in Development
RNA in Disease and Development > RNA in Disease

Access to this WIREs title is by subscription only.

Recommend to Your
Librarian Now!

The latest WIREs articles in your inbox

Sign Up for Article Alerts