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WIREs Syst Biol Med
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8th International Conference on Pathways, Networks, and Systems Medicine

Each year, Aegean Conferences organizes an international conference where biomedical researchers engaged in systems biology-related efforts present their latest research developments. This collection contains peer-reviewed articles of conference presentations from the 8th International Conference on Pathways, Networks, and Systems Medicine, held in June 2010.

Pathways, networks, and systems medicine—the meeting place of the Aegean and the mind
Editorial Commentary
WIREs Systems Biology and Medicine
Published Online: Apr 01 2011
DOI: 10.1002/wsbm.153
Abstract Full article on Wiley Online Library:   PDF
Integration of cardiovascular regulation by the blood/endothelium cell‐free layer
Advanced Review
WIREs Systems Biology and Medicine
Published Online: Apr 26 2011
DOI: 10.1002/wsbm.150
Abstract Full article on Wiley Online Library:   HTML | PDF
Drug repurposing and adverse event prediction using high‐throughput literature analysis
Advanced Review
WIREs Systems Biology and Medicine
Published Online: Feb 16 2011
DOI: 10.1002/wsbm.147
Abstract Full article on Wiley Online Library:   HTML | PDF
Mathematical models in biology: from molecules to life
Advanced Review
WIREs Systems Biology and Medicine
Published Online: Feb 18 2011
DOI: 10.1002/wsbm.142
Abstract Full article on Wiley Online Library:   HTML | PDF
International Conference on Pathways, Networks, and Systems Medicine
Click here for articles by speakers from
the 9th annual conference in 2011.

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William J. Pavan

William J. Pavan

is interested in using genomic tools to understand how an embryo develops into a functioning organism. His group focuses on neural crest cells, a group of stem cells that differentiate into a wide variety of tissues in the bodys. Issues with the development of the neural crest cells can cause many diseases, ranging from Waardenburg syndrome to cleft lip and palate. Using genomic research tools, Dr. Pavan seeks to identify the genes necessary for normal neural crest cell development, specifically the ones which differentiate into melanocytes. At least 15 genes have been recognized as important in the development of neural crest cells, but there are likely hundreds of genes involved in total. Dr. Pavan’s lab often uses the models of neural crest cell disorders in mice in order to identify the genes needed for normal development. They then study how these genes function, and whether there are corresponding genes in humans that can cause human diseases.

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