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Cancer: A Systems Approach

A collection of articles published in WIREs Systems Biology and Medicine on cancer research or related topics.

DNA methylation alterations in multiple myeloma as a model for epigenetic changes in cancer
Advanced Review
WIREs Systems Biology and Medicine
Amy Sharma,Christoph J. Heuck,Melissa J. Fazzari,Jayesh Mehta,Seema Singhal,John M. Greally,Amit Verma
Published Online: Mar 24 2010
DOI: 10.1002/wsbm.89
Abstract Full article on Wiley Online Library:   HTML | PDF
In silico models of cancer
Advanced Review
WIREs Systems Biology and Medicine
Lucas B. Edelman,James A. Eddy,Nathan D. Price
Published Online: Nov 20 2009
DOI: 10.1002/wsbm.75
Abstract Full article on Wiley Online Library:   HTML | PDF
A systems biology approach to defining metastatic biomarkers and signaling pathways
Focus Article
WIREs Systems Biology and Medicine
Natalie E. Goldberger,Kent W. Hunter
Published Online: May 04 2009
DOI: 10.1002/wsbm.6
Abstract Full article on Wiley Online Library:   HTML | PDF
Networks and pathways in pigmentation, health, and disease
Focus Article
WIREs Systems Biology and Medicine
Laura L. Baxter,Stacie K. Loftus,William J. Pavan
Published Online: Apr 29 2009
DOI: 10.1002/wsbm.20
Abstract Full article on Wiley Online Library:   HTML | PDF
Modeling breast biomechanics for multi‐modal image analysis—successes and challenges
Advanced Review
WIREs Systems Biology and Medicine
Vijay Rajagopal,Poul M. F. Nielsen,Martyn P. Nash
Published Online: Oct 28 2009
DOI: 10.1002/wsbm.58
Abstract Full article on Wiley Online Library:   HTML | PDF
The critical protein interactions and structures that elicit growth deregulation in cancer and viral replication
Focus Article
WIREs Systems Biology and Medicine
Horng D. Ou,Andrew P. May,Clodagh C. O'Shea
Published Online: Apr 15 2010
DOI: 10.1002/wsbm.88
Abstract Full article on Wiley Online Library:   HTML | PDF
Intercellular adhesion: mechanisms for growth and metastasis of epithelial cancers
Focus Article
WIREs Systems Biology and Medicine
Eric M. Balzer,Konstantinos Konstantopoulos
Published Online: Sep 12 2011
DOI: 10.1002/wsbm.160
Abstract Full article on Wiley Online Library:   HTML | PDF
Estrogen receptor‐positive breast cancer: a multidisciplinary challenge
Focus Article
WIREs Systems Biology and Medicine
Wilbert Zwart,Vasiliki Theodorou,Jason S. Carroll
Published Online: Jul 26 2010
DOI: 10.1002/wsbm.109
Abstract Full article on Wiley Online Library:   HTML | PDF
Mechanistic modeling to investigate signaling by oncogenic Ras mutants
Focus Article
WIREs Systems Biology and Medicine
Edward C. Stites,Kodi S. Ravichandran
Published Online: Jul 15 2011
DOI: 10.1002/wsbm.156
Abstract Full article on Wiley Online Library:   HTML | PDF
Hybrid models of tumor growth
Focus Article
WIREs Systems Biology and Medicine
Katarzyna A. Rejniak,Alexander R. A. Anderson
Published Online: Jul 07 2010
DOI: 10.1002/wsbm.102
Abstract Full article on Wiley Online Library:   HTML | PDF
Integrative physical oncology
Opinion
WIREs Systems Biology and Medicine
Haralampos Hatzikirou,Arnaud Chauviere,Amy L. Bauer,André Leier,Michael T. Lewis,Paul Macklin,Tatiana T. Marquez‐Lago,Elaine L. Bearer,Vittorio Cristini
Published Online: Aug 18 2011
DOI: 10.1002/wsbm.158
Abstract Full article on Wiley Online Library:   HTML | PDF
Normal morphogenesis of epithelial tissues and progression of epithelial tumors
Advanced Review
WIREs Systems Biology and Medicine
Chun‐Chao Wang,Leen Jamal,Kevin A. Janes
Published Online: Sep 02 2011
DOI: 10.1002/wsbm.159
Abstract Full article on Wiley Online Library:   HTML | PDF

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