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WIREs Nanomed Nanobiotechnol
Impact Factor: 5.186

Therapeutics: An Interdisciplinary View

A collection of articles published throughout the Wiley Interdisciplinary Reviews (WIREs) series on the treatment of various acute and chronic diseases.

Systems pharmacology, pharmacogenetics, and clinical trial design in network medicine
Advanced Review
WIREs Systems Biology and Medicine
Published Online: May 11 2012
DOI: 10.1002/wsbm.1173
Abstract Full article on Wiley Online Library:   HTML | PDF
Dendrimers—revolutionary drugs for infectious diseases
Overview
WIREs Nanomedicine and Nanobiotechnology
Published Online: Jul 03 2012
DOI: 10.1002/wnan.1181
Abstract Full article on Wiley Online Library:   HTML | PDF
Small molecule screening in zebrafish: swimming in potential drug therapies
Focus Article
WIREs Developmental Biology
Published Online: Feb 28 2012
DOI: 10.1002/wdev.37
Abstract Full article on Wiley Online Library:   HTML | PDF
Cannabinoid receptors and neurodegenerative diseases
Advanced Review
WIREs Membrane Transport and Signaling
Published Online: Aug 07 2012
DOI: 10.1002/wmts.64
Abstract Full article on Wiley Online Library:   HTML | PDF
Harnessing the power of cell‐penetrating peptides: activatable carriers for targeting systemic delivery of cancer therapeutics and imaging agents
Advanced Review
WIREs Nanomedicine and Nanobiotechnology
Published Online: Sep 13 2012
DOI: 10.1002/wnan.1197
Abstract Full article on Wiley Online Library:   HTML | PDF
Peptide delivery using phospholipid micelles
Advanced Review
WIREs Nanomedicine and Nanobiotechnology
Published Online: Jul 30 2012
DOI: 10.1002/wnan.1185
Abstract Full article on Wiley Online Library:   HTML | PDF
Smart polymersomes for therapy and diagnosis: fast progress toward multifunctional biomimetic nanomedicines
Advanced Review
WIREs Nanomedicine and Nanobiotechnology
Published Online: Jul 03 2012
DOI: 10.1002/wnan.1183
Abstract Full article on Wiley Online Library:   HTML | PDF
Cytolytic peptide nanoparticles (‘NanoBees’) for cancer therapy
Focus Article
WIREs Nanomedicine and Nanobiotechnology
Published Online: Jan 10 2011
DOI: 10.1002/wnan.126
Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of pro‐angiogenic therapies targeting the VEGF system
Focus Article
WIREs Systems Biology and Medicine
Published Online: Apr 07 2010
DOI: 10.1002/wsbm.92
Abstract Full article on Wiley Online Library:   HTML | PDF
Nanotechnology and HIV: potential applications for treatment and prevention
Focus Article
WIREs Nanomedicine and Nanobiotechnology
Published Online: Sep 21 2010
DOI: 10.1002/wnan.118
Abstract Full article on Wiley Online Library:   HTML | PDF
Systems vaccinology: learning to compute the behavior of vaccine induced immunity
Focus Article
WIREs Systems Biology and Medicine
Published Online: Oct 19 2011
DOI: 10.1002/wsbm.163
Abstract Full article on Wiley Online Library:   HTML | PDF
Regenerative nanomedicine and the treatment of degenerative retinal diseases
Focus Article
WIREs Nanomedicine and Nanobiotechnology
Published Online: Dec 14 2011
DOI: 10.1002/wnan.167
Abstract Full article on Wiley Online Library:   HTML | PDF
RNA decay: a novel therapeutic target in bacteria
Focus Article
WIREs RNA
Published Online: Feb 28 2012
DOI: 10.1002/wrna.1110
Abstract Full article on Wiley Online Library:   HTML | PDF
Nanotechnology in interventional cardiology
Focus Article
WIREs Nanomedicine and Nanobiotechnology
Published Online: Jul 11 2011
DOI: 10.1002/wnan.154
Abstract Full article on Wiley Online Library:   HTML | PDF
Nanotherapeutic approaches for the treatment of rheumatoid arthritis
Advanced Review
WIREs Nanomedicine and Nanobiotechnology
Published Online: Aug 11 2011
DOI: 10.1002/wnan.157
Abstract Full article on Wiley Online Library:   HTML | PDF
Functionalized radioactive gold nanoparticles in tumor therapy
Advanced Review
WIREs Nanomedicine and Nanobiotechnology
Published Online: Sep 22 2011
DOI: 10.1002/wnan.161
Abstract Full article on Wiley Online Library:   HTML | PDF
Suppression of nonsense mutations as a therapeutic approach to treat genetic diseases
Advanced Review
WIREs RNA
Published Online: Jul 06 2011
DOI: 10.1002/wrna.95
Abstract Full article on Wiley Online Library:   HTML | PDF
New biotechnological and nanomedicine strategies for treatment of lysosomal storage disorders
Advanced Review
WIREs Nanomedicine and Nanobiotechnology
Published Online: Jan 28 2010
DOI: 10.1002/wnan.73
Abstract Full article on Wiley Online Library:   HTML | PDF
Lipid‐sensing nuclear receptors in the pathophysiology and treatment of the metabolic syndrome
Advanced Review
WIREs Systems Biology and Medicine
Published Online: Feb 16 2011
DOI: 10.1002/wsbm.137
Abstract Full article on Wiley Online Library:   HTML | PDF
Nanotechnology and the treatment of inner ear diseases
Focus Article
WIREs Nanomedicine and Nanobiotechnology
Published Online: Feb 04 2011
DOI: 10.1002/wnan.125
Abstract Full article on Wiley Online Library:   HTML | PDF
Microchips and controlled‐release drug reservoirs
Advanced Review
WIREs Nanomedicine and Nanobiotechnology
Published Online: Jun 01 2010
DOI: 10.1002/wnan.93
Abstract Full article on Wiley Online Library:   HTML | PDF
Emerging clinical applications in cardiovascular pharmacogenomics
Advanced Review
WIREs Systems Biology and Medicine
Published Online: Aug 20 2010
DOI: 10.1002/wsbm.113
Abstract Full article on Wiley Online Library:   HTML | PDF
Electrically active nanomaterials as improved neural tissue regeneration scaffolds
Advanced Review
WIREs Nanomedicine and Nanobiotechnology
Published Online: Aug 20 2010
DOI: 10.1002/wnan.109
Abstract Full article on Wiley Online Library:   HTML | PDF
Nanostructured bladder tissue replacements
Advanced Review
WIREs Nanomedicine and Nanobiotechnology
Published Online: Aug 20 2010
DOI: 10.1002/wnan.89
Abstract Full article on Wiley Online Library:   HTML | PDF
Tissue scaffolds for skin wound healing and dermal reconstruction
Advanced Review
WIREs Nanomedicine and Nanobiotechnology
Published Online: Jul 06 2010
DOI: 10.1002/wnan.100
Abstract Full article on Wiley Online Library:   HTML | PDF
Nanoscale surfacing for regenerative medicine
Advanced Review
WIREs Nanomedicine and Nanobiotechnology
Published Online: Apr 13 2010
DOI: 10.1002/wnan.74
Abstract Full article on Wiley Online Library:   HTML | PDF
Axon repair: surgical application at a subcellular scale
Advanced Review
WIREs Nanomedicine and Nanobiotechnology
Published Online: Jan 25 2010
DOI: 10.1002/wnan.76
Abstract Full article on Wiley Online Library:   HTML | PDF
Machine learning methods for predicting tumor response in lung cancer
Focus Article
WIREs Data Mining and Knowledge Discovery
Published Online: Jan 30 2012
DOI: 10.1002/widm.1047
Abstract Full article on Wiley Online Library:   HTML | PDF
In vivo injectable gels for tissue repair
Advanced Review
WIREs Nanomedicine and Nanobiotechnology
Published Online: Jul 21 2011
DOI: 10.1002/wnan.91
Abstract Full article on Wiley Online Library:   HTML | PDF
Emerging applications of nanotechnology for the diagnosis and management of vulnerable atherosclerotic plaques
Advanced Review
WIREs Nanomedicine and Nanobiotechnology
Published Online: Aug 10 2011
DOI: 10.1002/wnan.158
Abstract Full article on Wiley Online Library:   HTML | PDF
Novel approaches for drug delivery systems in nanomedicine: effects of particle design and shape
Advanced Review
WIREs Nanomedicine and Nanobiotechnology
Published Online: Dec 02 2011
DOI: 10.1002/wnan.165
Abstract Full article on Wiley Online Library:   HTML | PDF
P2X7 receptors and epithelial cancers
Focus Article
WIREs Membrane Transport and Signaling
Published Online: Jan 11 2012
DOI: 10.1002/wmts.33
Abstract Full article on Wiley Online Library:   HTML | PDF

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In the Spotlight

Robert Langer

Robert Langer

works at the interface of biotechnology and materials science. His lab is researching many topics, such as investigating the mechanism of release from polymeric delivery systems with concomitant microstructural analysis and mathematical modeling; studying applications of these systems including the development of effective long-term delivery systems for insulin, anti-cancer drugs, growth factors, gene therapy agents and vaccines; developing controlled release systems that can be magnetically, ultrasonically, or enzymatically triggered to increase release rates; synthesizing new biodegradable polymeric delivery systems which will ultimately be absorbed by the body; creating new approaches for delivering drugs such as proteins and genes across complex barriers such as the blood-brain barrier, the intestine, the lung and the skin; stem cell research including controlling growth and differentiation; and creating new biomaterials with shape memory or surface switching properties.

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