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WIREs Syst Biol Med
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9th International Conference on Pathways, Networks, and Systems Medicine

Each year, Aegean Conferences organizes an international conference where biomedical researchers engaged in systems biology-related efforts present their latest research developments. This collection contains peer-reviewed articles of conference presentations from the 9th International Conference on Pathways, Networks, and Systems Medicine, held in June 2011.

Pathways, networks, and systems medicine—the meeting place of the Aegean and the mind
Editorial Commentary
WIREs Systems Biology and Medicine
Published Online: Apr 01 2011
DOI: 10.1002/wsbm.153
Abstract Full article on Wiley Online Library:   PDF
Understanding multimodal biological decisions from single cell and population dynamics
Advanced Review
WIREs Systems Biology and Medicine
Published Online: May 14 2012
DOI: 10.1002/wsbm.1175
Abstract Full article on Wiley Online Library:   HTML | PDF
Recent approaches to the prioritization of candidate disease genes
Advanced Review
WIREs Systems Biology and Medicine
Published Online: Jun 11 2012
DOI: 10.1002/wsbm.1177
Abstract Full article on Wiley Online Library:   HTML | PDF
Decoding the functions of post‐transcriptional regulators in the determination of inflammatory states: focus on macrophage activation
Focus Article
WIREs Systems Biology and Medicine
Published Online: Jul 03 2012
DOI: 10.1002/wsbm.1179
Abstract Full article on Wiley Online Library:   HTML | PDF

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William J. Pavan

William J. Pavan

is interested in using genomic tools to understand how an embryo develops into a functioning organism. His group focuses on neural crest cells, a group of stem cells that differentiate into a wide variety of tissues in the bodys. Issues with the development of the neural crest cells can cause many diseases, ranging from Waardenburg syndrome to cleft lip and palate. Using genomic research tools, Dr. Pavan seeks to identify the genes necessary for normal neural crest cell development, specifically the ones which differentiate into melanocytes. At least 15 genes have been recognized as important in the development of neural crest cells, but there are likely hundreds of genes involved in total. Dr. Pavan’s lab often uses the models of neural crest cell disorders in mice in order to identify the genes needed for normal development. They then study how these genes function, and whether there are corresponding genes in humans that can cause human diseases.

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