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Aegean Conferences on Pathways, Networks, and Systems Medicine

Aegean Conferences organizes international meetings on Pathways, Networks, and Systems Medicine where biomedical researchers engaged in systems biology-related efforts present their latest research developments. This collection contains peer-reviewed review articles containing information on the research areas presented at these conferences.

13th Conference, 2019

Modeling immune cell behavior across scales in cancer
Advanced Review
WIREs WIREs Systems Biology and Medicine
Sahak Z. Makaryan,Colin G. Cess,Stacey D. Finley
Published Online: Mar 04 2020
DOI: 10.1002/wsbm.1484
Abstract Full article on Wiley Online Library:   HTML | PDF
Lipidomics: Current state of the art in a fast moving field
Focus Article
WIREs WIREs Systems Biology and Medicine
Valerie B. O'Donnell,Kim Ekroos,Gerhard Liebisch,Michael Wakelam
Published Online: Oct 23 2019
DOI: 10.1002/wsbm.1466
Abstract Full article on Wiley Online Library:   HTML | PDF
Intracellular signaling dynamics and their role in coordinating tissue repair
Focus Article
WIREs WIREs Systems Biology and Medicine
Samuel J. Ghilardi,Breanna M. O'Reilly,Allyson E. Sgro
Published Online: Feb 08 2020
DOI: 10.1002/wsbm.1479
Abstract Full article on Wiley Online Library:   HTML | PDF
How personalized heart modeling can help treatment of lethal arrhythmias: A focus on ventricular tachycardia ablation strategies in post‐infarction patients
Advanced Review
WIREs WIREs Systems Biology and Medicine
Natalia A. Trayanova,Ashish N. Doshi,Adityo Prakosa
Published Online: Jan 09 2020
DOI: 10.1002/wsbm.1477
Abstract Full article on Wiley Online Library:   HTML | PDF
The evolution of genomic imprinting: Epigenetic control of mammary gland development and postnatal resource control
Focus Article
WIREs WIREs Systems Biology and Medicine
Geula Hanin,Anne C. Ferguson‐Smith
Published Online: Dec 26 2019
DOI: 10.1002/wsbm.1476
Abstract Full article on Wiley Online Library:   HTML | PDF
Cholesterol interaction motifs in G protein‐coupled receptors: Slippery hot spots?
Advanced Review
WIREs WIREs Systems Biology and Medicine
Parijat Sarkar,Amitabha Chattopadhyay
Published Online: Feb 07 2020
DOI: 10.1002/wsbm.1481
Abstract Full article on Wiley Online Library:   HTML | PDF

12th Conference, 2017

Human microbiota, blood group antigens, and disease
Advanced Review
WIREs WIREs Systems Biology and Medicine
D. Rose Ewald,Susan C.J. Sumner
Published Online: Jan 09 2018
DOI: 10.1002/wsbm.1413
Abstract Full article on Wiley Online Library:   HTML | PDF
Diversification of transcription factor–DNA interactions and the evolution of gene regulatory networks
Advanced Review
WIREs WIREs Systems Biology and Medicine
Julia M. Rogers,Martha L. Bulyk
Published Online: Apr 25 2018
DOI: 10.1002/wsbm.1423
Abstract Full article on Wiley Online Library:   HTML | PDF
Cell cycle regulation of folate‐mediated one‐carbon metabolism
Advanced Review
WIREs WIREs Systems Biology and Medicine
Xu Lan,Martha S. Field,Patrick J. Stover
Published Online: Jun 11 2018
DOI: 10.1002/wsbm.1426
Abstract Full article on Wiley Online Library:   HTML | PDF

11th Conference, 2015

Therapeutic genome engineering via CRISPR‐Cas systems
Advanced Review
WIREs WIREs Systems Biology and Medicine
Ana M. Moreno,Prashant Mali
Published Online: Feb 15 2017
DOI: 10.1002/wsbm.1380
Abstract Full article on Wiley Online Library:   HTML | PDF
In search for symmetries in the metabolism of cancer
Advanced Review
WIREs WIREs Systems Biology and Medicine
Francesco Gatto,Jens Nielsen
Published Online: Nov 05 2015
DOI: 10.1002/wsbm.1321
Abstract Full article on Wiley Online Library:   HTML | PDF
Mitochondrial metabolic remodeling in response to genetic and environmental perturbations
Advanced Review
WIREs WIREs Systems Biology and Medicine
Kate E.R. Hollinshead,Daniel A. Tennant
Published Online: May 19 2016
DOI: 10.1002/wsbm.1334
Abstract Full article on Wiley Online Library:   HTML | PDF
Data sources for in vivo molecular profiling of human phenotypes
Advanced Review
WIREs WIREs Systems Biology and Medicine
Timothy Cardozo,Priyanka Gupta,Eric Ni,Lauren M. Young,Doreen Tivon,Klara Felsovalyi
Published Online: Sep 07 2016
DOI: 10.1002/wsbm.1354
Abstract Full article on Wiley Online Library:   HTML | PDF
Modeling calcium regulation of contraction, energetics, signaling, and transcription in the cardiac myocyte
Advanced Review
WIREs WIREs Systems Biology and Medicine
Raimond L. Winslow,Mark A. Walker,Joseph L. Greenstein
Published Online: Nov 12 2015
DOI: 10.1002/wsbm.1322
Abstract Full article on Wiley Online Library:   HTML | PDF
Role of frameshift ubiquitin B protein in Alzheimer's disease
Advanced Review
WIREs WIREs Systems Biology and Medicine
Xin Chen,Dina Petranovic
Published Online: May 30 2016
DOI: 10.1002/wsbm.1340
Abstract Full article on Wiley Online Library:   HTML | PDF
Systems medicine in colorectal cancer: from a mathematical model toward a new type of clinical trial
Advanced Review
WIREs WIREs Systems Biology and Medicine
Nicoletta Castagnino,Massimo Maffei,Lorenzo Tortolina,Gabriele Zoppoli,Daniela Piras,Alessio Nencioni,Eva Moran,Alberto Ballestrero,Franco Patrone,Silvio Parodi
Published Online: May 30 2016
DOI: 10.1002/wsbm.1342
Abstract Full article on Wiley Online Library:   HTML | PDF

10th Conference, 2012

Modeling cellular compartmentation in one‐carbon metabolism
Advanced Review
WIREs WIREs Systems Biology and Medicine
Marco Scotti,Lorenzo Stella,Emily J. Shearer,Patrick J. Stover
Published Online: Feb 13 2013
DOI: 10.1002/wsbm.1209
Abstract Full article on Wiley Online Library:   HTML | PDF

9th Conference, 2011

Understanding multimodal biological decisions from single cell and population dynamics
Advanced Review
WIREs WIREs Systems Biology and Medicine
Kumar Selvarajoo
Published Online: May 14 2012
DOI: 10.1002/wsbm.1175
Abstract Full article on Wiley Online Library:   HTML | PDF
Recent approaches to the prioritization of candidate disease genes
Advanced Review
WIREs WIREs Systems Biology and Medicine
Nadezhda T. Doncheva,Tim Kacprowski,Mario Albrecht
Published Online: Jun 11 2012
DOI: 10.1002/wsbm.1177
Abstract Full article on Wiley Online Library:   HTML | PDF
Decoding the functions of post‐transcriptional regulators in the determination of inflammatory states: focus on macrophage activation
Focus Article
WIREs WIREs Systems Biology and Medicine
Panagiota Kafasla,Ioannis Karakasiliotis,Dimitris L. Kontoyiannis
Published Online: Jul 03 2012
DOI: 10.1002/wsbm.1179
Abstract Full article on Wiley Online Library:   HTML | PDF

8th Conference, 2010

Mathematical models in biology: from molecules to life
Advanced Review
WIREs WIREs Systems Biology and Medicine
Yiannis N. Kaznessis
Published Online: Feb 18 2011
DOI: 10.1002/wsbm.142
Abstract Full article on Wiley Online Library:   HTML | PDF
Functional genomics of the brain: uncovering networks in the CNS using a systems approach
Advanced Review
WIREs WIREs Systems Biology and Medicine
Genevieve Konopka
Published Online: Dec 31 2010
DOI: 10.1002/wsbm.139
Abstract Full article on Wiley Online Library:   HTML | PDF
Integration of cardiovascular regulation by the blood/endothelium cell‐free layer
Advanced Review
WIREs WIREs Systems Biology and Medicine
C. Makena Hightower,Beatriz Y. Salazar Vázquez,Sung Woo Park,Krishna Sriram,Judith Martini,Ozlem Yalcin,Amy G. Tsai,Pedro Cabrales,Daniel M. Tartakovsky,Paul C. Johnson,Marcos Intaglietta
Published Online: Apr 26 2011
DOI: 10.1002/wsbm.150
Abstract Full article on Wiley Online Library:   HTML | PDF
Drug repurposing and adverse event prediction using high‐throughput literature analysis
Advanced Review
WIREs WIREs Systems Biology and Medicine
Spyros N. Deftereos,Christos Andronis,Ellen J. Friedla,Aris Persidis,Andreas Persidis
Published Online: Feb 16 2011
DOI: 10.1002/wsbm.147
Abstract Full article on Wiley Online Library:   HTML | PDF
Regulatory gene network circuits underlying T cell development from multipotent progenitors
Advanced Review
WIREs WIREs Systems Biology and Medicine
Hao Yuan Kueh,Ellen V. Rothenberg
Published Online: Oct 04 2011
DOI: 10.1002/wsbm.162
Abstract Full article on Wiley Online Library:   HTML | PDF
Potential role of atomic force microscopy in systems biology
Advanced Review
WIREs WIREs Systems Biology and Medicine
Srinivasan Ramachandran,Fernando Teran Arce,Ratnesh Lal
Published Online: Jul 15 2011
DOI: 10.1002/wsbm.154
Abstract Full article on Wiley Online Library:   HTML | PDF
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