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WIREs RNA
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Microbes and RNA – Not Something to Sneeze At

You’ve heard the phrase "don’t kill the messenger," but what if the "messenger" (e.g., mRNA) was inherently designed to kill you? A key frontier in understanding the pathogenesis of many infectious diseases is the role of microbial RNAs. Groundbreaking discoveries from CRISPR to riboswitches have established RNA-based processes as novel, fascinating, and powerful entities in the microbial world. It's a pretty good bet that there's a lot more out there to be discovered.

This collection provides a set of accessible articles on various aspects of RNA biology in microbial systems. We hope that they will bring you up to speed on several interesting aspects of microbial molecular biology, and also stoke your interest to investigate and expand our understanding of RNAs in the microbial world.

Jeff Wilusz, Editor in Chief, WIREs RNA

Introduction

Microbes and RNA – Not Something to Sneeze At
Editorial Commentary
WIREs RNA
Published Online: Aug 17 2017
DOI: 10.1002/wrna.1439
Abstract Full article on Wiley Online Library:   PDF

Bacteriology

Ligand‐dependent ribozymes
Advanced Review
WIREs RNA
Published Online: Sep 30 2016
DOI: 10.1002/wrna.1395
Abstract Full article on Wiley Online Library:   HTML | PDF
The role of mRNA structure in bacterial translational regulation
Advanced Review
WIREs RNA
Published Online: Jun 14 2016
DOI: 10.1002/wrna.1370
Abstract Full article on Wiley Online Library:   HTML | PDF
Riboregulation of bacterial and archaeal transposition
Advanced Review
WIREs RNA
Published Online: Feb 04 2016
DOI: 10.1002/wrna.1341
Abstract Full article on Wiley Online Library:   HTML | PDF
Group II introns: versatile ribozymes and retroelements
Advanced Review
WIREs RNA
Published Online: Feb 15 2016
DOI: 10.1002/wrna.1339
Abstract Full article on Wiley Online Library:   HTML | PDF
Regulation and functions of bacterial PNPase
Advanced Review
WIREs RNA
Published Online: Jan 11 2016
DOI: 10.1002/wrna.1328
Abstract Full article on Wiley Online Library:   HTML | PDF
Structure and mechanism of the T‐box riboswitches
Advanced Review
WIREs RNA
Published Online: May 08 2015
DOI: 10.1002/wrna.1285
Abstract Full article on Wiley Online Library:   HTML | PDF

Virology

Small molecules targeting viral RNA
Opinion
WIREs RNA
Published Online: Jun 16 2016
DOI: 10.1002/wrna.1373
Abstract Full article on Wiley Online Library:   HTML | PDF
Virus‐derived small RNAs: molecular footprints of host–pathogen interactions
Advanced Review
WIREs RNA
Published Online: May 12 2016
DOI: 10.1002/wrna.1361
Abstract Full article on Wiley Online Library:   HTML | PDF
The evolving world of small RNAs from RNA viruses
Advanced Review
WIREs RNA
Published Online: Apr 05 2016
DOI: 10.1002/wrna.1351
Abstract Full article on Wiley Online Library:   HTML | PDF
A structurally plastic ribonucleoprotein complex mediates post‐transcriptional gene regulation in HIV ‐1
Advanced Review
WIREs RNA
Published Online: Mar 01 2016
DOI: 10.1002/wrna.1342
Abstract Full article on Wiley Online Library:   HTML | PDF
Prohead RNA : a noncoding viral RNA of novel structure and function
Advanced Review
WIREs RNA
Published Online: Jan 25 2016
DOI: 10.1002/wrna.1330
Abstract Full article on Wiley Online Library:   HTML | PDF
The KSHV RNA regulator ORF57 : target specificity and its role in the viral life cycle
Advanced Review
WIREs RNA
Published Online: Jan 14 2016
DOI: 10.1002/wrna.1323
Abstract Full article on Wiley Online Library:   HTML | PDF
Nucleocapsid proteins: roles beyond viral RNA packaging
Advanced Review
WIREs RNA
Published Online: Jan 08 2016
DOI: 10.1002/wrna.1326
Abstract Full article on Wiley Online Library:   HTML | PDF
lncRNAs regulate the innate immune response to viral infection
Advanced Review
WIREs RNA
Published Online: Dec 15 2015
DOI: 10.1002/wrna.1321
Abstract Full article on Wiley Online Library:   HTML | PDF
Satellite RNA pathogens of plants: impacts and origins—an RNA silencing perspective
Advanced Review
WIREs RNA
Published Online: Oct 20 2015
DOI: 10.1002/wrna.1311
Abstract Full article on Wiley Online Library:   HTML | PDF
Roles of microRNAs and long‐noncoding RNAs in human immunodeficiency virus replication
Advanced Review
WIREs RNA
Published Online: Sep 22 2015
DOI: 10.1002/wrna.1308
Abstract Full article on Wiley Online Library:   HTML | PDF
Understanding the potential of hepatitis C virus internal ribosome entry site domains to modulate translation initiation via their structure and function
Advanced Review
WIREs RNA
Published Online: Oct 28 2014
DOI: 10.1002/wrna.1268
Abstract Full article on Wiley Online Library:   HTML | PDF

Parasitology

Translational regulation in blood stages of the malaria parasite Plasmodium spp. : systems‐wide studies pave the way
Advanced Review
WIREs RNA
Published Online: May 26 2016
DOI: 10.1002/wrna.1365
Abstract Full article on Wiley Online Library:   HTML | PDF
Trypanosome RNA editing: the complexity of getting U in and taking U out
Advanced Review
WIREs RNA
Published Online: Nov 02 2015
DOI: 10.1002/wrna.1313
Abstract Full article on Wiley Online Library:   HTML | PDF

Mycology

mRNA decay: an adaptation tool for the environmental fungal pathogen Cryptococcus neoformans
Focus Article
WIREs RNA
Published Online: May 19 2017
DOI: 10.1002/wrna.1424
Abstract Full article on Wiley Online Library:   HTML | PDF
Insights into RNA structure and dynamics from recent NMR and X‐ray studies of the Neurospora Varkud satellite ribozyme
Advanced Review
WIREs RNA
Published Online: Apr 06 2017
DOI: 10.1002/wrna.1421
Abstract Full article on Wiley Online Library:   HTML | PDF

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