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WIREs Nanomed Nanobiotechnol
Impact Factor: 7.689

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Wiley Interdisciplinary Reviews:
WIREs Nanomedicine and Nanobiotechnology
Volume 12 Issue 4 (July 2020)
Page 0 - 0

Cover Image

Cover Image, Volume 12, Issue 4
Published Online: Jun 05 2020
DOI: 10.1002/wnan.1655
The cover image is based on the Advanced Review 2D and 3D electrospinning technologies for the fabrication of nanofibrous scaffolds for skin tissue engineering: A review, by Antonios Keirouz, Michael Chung, Jaehoon Kwon, Giuseppino Fortunato and Norbert Radacsi. https://doi.org/10.1002/wnan.1626.
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Overview

Phage nanofibers in nanomedicine: Biopanning for early diagnosis, targeted therapy, and proteomics analysis
Published Online: Mar 08 2020
DOI: 10.1002/wnan.1623
Phages can be used as a platform to discover peptides or proteins that can target cells (such as cancer cells and stem cells), tissues (such as tumors), signaling pathways, or immune checkpoints. These peptides or proteins as well as phages bearing them can be used to develop nanomedicines for early diagnosis, targeted therapy, and proteomics analysis.
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Advanced Reviews

Emerging methods in therapeutics using multifunctional nanoparticles
Published Online: Mar 20 2020
DOI: 10.1002/wnan.1625
Novel approaches in designing nanoparticles to overcome challenges faced by traditional nanoparticle‐based drug delivery systems.
Abstract Full article on Wiley Online Library:   HTML | PDF
2D and 3D electrospinning technologies for the fabrication of nanofibrous scaffolds for skin tissue engineering: A review
Published Online: Mar 12 2020
DOI: 10.1002/wnan.1626
Engineered 2D and 3D electrospun nanomaterials are being extensively examined toward their ability to provide a biomimetic niche that integrates the appropriate architecture and material to tissue interface capacities to stimulate better healing and accelerate skin regeneration.
Abstract Full article on Wiley Online Library:   HTML | PDF
Tailoring nanoparticles based on boron dipyrromethene for cancer imaging and therapy
Published Online: Mar 12 2020
DOI: 10.1002/wnan.1627
Boron dipyrromethene nanoparticles which can be formed via self‐assembly of small molecules, chemical conjugation, and physical encapsulation are widely used for cellular imaging, near‐infrared fluorescence imaging, computed tomography imaging, photoacoustic imaging, phototherapy, and theranostics.
Abstract Full article on Wiley Online Library:   HTML | PDF
Image‐guided tumor surgery: The emerging role of nanotechnology
Published Online: Mar 11 2020
DOI: 10.1002/wnan.1624
Nanoparticles reported for surgical guidance.
Abstract Full article on Wiley Online Library:   HTML | PDF
Progress in extracellular vesicle biology and their application in cancer medicine
Published Online: Mar 04 2020
DOI: 10.1002/wnan.1621
Landscape of extracellular vesicles in biology and disease.
Abstract Full article on Wiley Online Library:   HTML | PDF
Molecular imaging of extracellular matrix proteins with targeted probes using magnetic resonance imaging
Published Online: Mar 03 2020
DOI: 10.1002/wnan.1622
Direction of visualization of biological processes and pathological alterations at cellular and molecular levels with extracellular matrix targeted magnetic resonance imaging probes.
Abstract Full article on Wiley Online Library:   HTML | PDF
Regulation of cancer‐immunity cycle and tumor microenvironment by nanobiomaterials to enhance tumor immunotherapy
Published Online: Mar 01 2020
DOI: 10.1002/wnan.1612
Overview of the process of the cancer‐immunity cycle and the targets, mediation of cancer immunotherapies by nanobiomaterials.
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Recent advances of smart acid‐responsive gold nanoparticles in tumor therapy
Published Online: Feb 10 2020
DOI: 10.1002/wnan.1619
Schematic illustration of smart acid‐responsive AuNPs proposed for tumor theranostics.
Abstract Full article on Wiley Online Library:   HTML | PDF
Fluorescent carbon dots as intracellular imaging probes
Published Online: Feb 10 2020
DOI: 10.1002/wnan.1617
Application potential of fluorescent carbon dot as intracellular imaging probe is described with the focus on relevant surface chemistry and functionalization.
Abstract Full article on Wiley Online Library:   HTML | PDF
Recent advances in photoacoustic contrast agents for in vivo imaging
Published Online: Feb 06 2020
DOI: 10.1002/wnan.1618
Schematic illustration of various types of contrast agents for photoacoustic imaging. NP: Nanoparticles; TMC: Transition metal chalcogenides.
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Impact of the protein corona on nanomaterial immune response and targeting ability
Published Online: Jan 30 2020
DOI: 10.1002/wnan.1615
Nanoparticles are usually employed as carriers of therapeutic agents (e.g. anticancer drugs) and surface functionalized to promote favorable interactions with target cells. When nanoparticles are administered in vivo, they get covered by a protein corona that activates the immune response and influences the targeted delivery of nanomedicine
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Protein‐based nanoplatforms for tumor imaging and therapy
Published Online: Jan 30 2020
DOI: 10.1002/wnan.1616
Schematic illustration of various protein‐based nanoplatforms for diverse tumor imaging and therapy methods. Inside the inner circle indicates several characteristic protein‐based nanoplatforms acquired with permission from Chen et al. (2019), Zhang, Chen, Ma, Wang, and Chen (2018), Zhang, Wang, Ma, Luo, and Chen (2019), and RCSB PDB (rcsb.org) of PDB ID 2FHA. (Upper and lower left: BSA‐based nanoplatforms; upper right: transferrin‐based nanoplatforms; lower right: ferritin‐based nanoplatforms.) CDT, chemodynamic therapy; Chemo‐T, chemotherapy; CT, X‐ray computed tomography; FL, fluorescence; MR, magnetic resonance; PA, photoacoustic; PDT, photodynamic therapy; PET, positron emission computed tomography; PTT, photothermal therapy; RT, radiotherapy. Note: Other imaging and therapy methods like SPECT imaging and immunotherapy are also involved in this review but not present in this scheme.
Abstract Full article on Wiley Online Library:   HTML | PDF
Physical virology: From virus self‐assembly to particle mechanics
Published Online: Jan 20 2020
DOI: 10.1002/wnan.1613
Viruses are highly ordered supramolecular complexes that have evolved to propagate between related organisms. Although viruses are very diverse, they share common functions and properties. In this review, we aim to provide an overview of virus self‐assembly and viral particle mechanics, summarizing the latest scientific achievements within these areas.
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Scale‐up of electrospinning technology: Applications in the pharmaceutical industry
Published Online: Dec 20 2019
DOI: 10.1002/wnan.1611
Application of scaled‐up electrospinning in oral drug delivery.
Abstract Full article on Wiley Online Library:   HTML | PDF

Focus Article

Stimuli‐activatable nanomedicines for chemodynamic therapy of cancer
Published Online: Feb 03 2020
DOI: 10.1002/wnan.1614
Schematic illustration of activatable nanomedicine for chemodynamic therapy (CDT). The ˙OH produced by intratumoral Fenton or Fenton‐like reactions could kill cancer cells effectively. CDT shows its own merits for cancer treatment, including highly specific toward the TME, highly toxicity ˙OH production, and reverse the hypoxia and immunosuppressive TME.
Abstract Full article on Wiley Online Library:   HTML | PDF

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