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WIREs Nanomed Nanobiotechnol
Impact Factor: 4.761

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Wiley Interdisciplinary Reviews:
Nanomedicine and Nanobiotechnology
Volume 9 Issue 5 (September/October 2017)
Page 0 - 0

Cover Image

Cover Image, Volume 9, Issue 5
Published Online: Aug 16 2017
DOI: 10.1002/wnan.1489
The cover image, by Altug Ozcelikkale et al., is based on the Advanced Review In vitro microfluidic models of tumor microenvironment to screen transport of drugs and nanoparticles, DOI: 10.1002/wnan.1460.
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Overviews

ELISA ‐type assays of trace biomarkers using microfluidic methods
Published Online: Feb 20 2017
DOI: 10.1002/wnan.1457
Micro open‐sandwich enzyme‐linked immunosorbent assay.
Abstract Full article on Wiley Online Library:   HTML | PDF
Renal clearable noble metal nanoparticles: photoluminescence, elimination, and biomedical applications
Published Online: Jan 10 2017
DOI: 10.1002/wnan.1453
Renal clearable luminescent metal nanoparticles.
Abstract Full article on Wiley Online Library:   HTML | PDF

Advanced Reviews

Nanomedicine approaches to improve cancer immunotherapy
Published Online: Mar 10 2017
DOI: 10.1002/wnan.1456
Several strategies of nanoimmunotherapy have been developed to kill cancer cells. Nanoparticles(NPs) can delivery adjuvants to induce dendritic cell (DC) maturation, meanwhile NPs can easily co‐deliver tumor antigens and adjuvants to DCs ensuring effective activation and presentation. Additionally, NPs can restore T cell antitumor function by delivering CTLA‐4 or PD‐1/PD‐L1 antibodies that stop anergy.
Abstract Full article on Wiley Online Library:   HTML | PDF
Pioneering medical advances through nanofluidic implantable technologies
Published Online: Mar 10 2017
DOI: 10.1002/wnan.1455
a) Render of a next‐generation, nanofluidic implantable system capable of active controlled delivery. (b and c) Illustration of how ion concentration polarization (ICP) is employed for active control. (d) Graph of dendritic fullerene 1 release modulation over 2 days. Interruption was accomplished with both bias directions.
Abstract Full article on Wiley Online Library:   HTML | PDF
Stimuli‐responsive liposomes for drug delivery
Published Online: Feb 15 2017
DOI: 10.1002/wnan.1450
Controlled drug delivery system using stimuli‐responsive liposomes
Abstract Full article on Wiley Online Library:   HTML | PDF
In vitro microfluidic models of tumor microenvironment to screen transport of drugs and nanoparticles
Published Online: Feb 14 2017
DOI: 10.1002/wnan.1460
Bridging the gap
Abstract Full article on Wiley Online Library:   HTML | PDF
Nanoescapology: progress toward understanding the endosomal escape of polymeric nanoparticles
Published Online: Feb 03 2017
DOI: 10.1002/wnan.1452
Nanoparticles have the potential to drastically improve the delivery of therapeutics, but their use is limited by their ability to escape endosomes after being internalized into cells. As new materials are engineered it is essential we understand how they behave in cells to overcome this substantial barrier.
Abstract Full article on Wiley Online Library:   HTML | PDF
The effects of nanomaterials on blood coagulation in hemostasis and thrombosis
Published Online: Jan 11 2017
DOI: 10.1002/wnan.1448
Effects of nanomaterials on blood platelets and plasma coagulation system.
Abstract Full article on Wiley Online Library:   HTML | PDF

Focus Article

Reengineering red blood cells for cellular therapeutics and diagnostics
Published Online: Jan 24 2017
DOI: 10.1002/wnan.1454
From bench to clinical experiences. Development of reengineered red blood cells as delivery systems for therapeutic and diagnostic applications: the route from in vitro studies up to clinical investigations through an industrial manufacturing.
Abstract Full article on Wiley Online Library:   HTML | PDF

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Mauro Ferrari

Mauro Ferrari

started out in mechanical engineering and became interested in nanotechnology with his studies on nanomechanics and nanofluidics. His research work and involvement with setting up some of the premier nano centers and alliances in the world, bringing together universities, hospitals, and federal agencies, showcases interdisciplinarity at work.

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