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WIREs Nanomed Nanobiotechnol
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Wiley Interdisciplinary Reviews:
Nanomedicine and Nanobiotechnology
Volume 9 Issue 6 (November/December 2017)
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Cover Image, Volume 9, Issue 6
Published Online: Oct 12 2017
DOI: 10.1002/wnan.1501
In the Overview by Sangtani and Nag et al., the authors detail recent advances in multifunctional therapeutic nanoparticles (NPs) for drug delivery and imaging. The distinction is made between hard NPs such as quantum dots and gold NPs (where drug cargos are attached to the NP surface) and soft NPs such as liposomes and micelles (which allow both core loading and surface attachment). The image shows a cut away view of a mammalian cell interfaced with soft (foreground left) and hard (foreground right) NPs during the delivery of surface‐appended (green spheres) and core‐loaded (red rods) cargos. Illustration is courtesy Ella Maru Studio, Inc. DOI: 10.1002/wnan.1466.
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Overviews

Targeted nanoparticles for head and neck cancers: overview and perspectives
Published Online: Apr 07 2017
DOI: 10.1002/wnan.1469
Head and neck cancer statistics worldwide.
Abstract Full article on Wiley Online Library:   HTML | PDF
Antibodies from plants for bionanomaterials
Published Online: Mar 27 2017
DOI: 10.1002/wnan.1462
Plants are ideal for making antibodies and other recombinant proteins. The agroinfiltration system is particularly useful due to its speed and scalability and represents a powerful tool for generating plant antibodies to analyse and construct nanomaterials. Many recombinant genes can be coexpressed efficiently and this greatly supports synthetic biology approaches and allows for the combination with, e.g., plant virus‐like particles to assemble antibody‐based supramolecular structures and scaffolds.
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Multifunctional nanoparticle composites: progress in the use of soft and hard nanoparticles for drug delivery and imaging
Published Online: Mar 16 2017
DOI: 10.1002/wnan.1466
Multifunctional therapeutic nanoparticles (NPs) encompass soft and hard NP materials and their implementation requires careful consideration of numerous critical factors.
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Protein corona and nanoparticles: how can we investigate on?
Published Online: Mar 15 2017
DOI: 10.1002/wnan.1467
Protein corona (PC) represents the ‘visible side’ of the NPs into the physiological enviroment influencing NP fate in vivo. The PC consists of two layers, known as hard corona (HC) and soft corona (SC). A multidisciplinary approach to investigate both these protein layers is strongly needed to better understand NP in vivo behaviour.
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Advanced Reviews

Magnetic resonance relaxation induced by superparamagnetic particles used as contrast agents in magnetic resonance imaging: a theoretical review
Published Online: Apr 11 2017
DOI: 10.1002/wnan.1468
Nuclear magnetic resonance (NMR) relaxation by superparamagnetic nanoparticles is modeled by water protons that diffuse in the magnetic field inhomogeneities the particles produce.
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Bio‐inspired nanomedicine strategies for artificial blood components
Published Online: Mar 15 2017
DOI: 10.1002/wnan.1464
Representative nanomedicine designs for bio‐inspired artificial blood components.
Abstract Full article on Wiley Online Library:   HTML | PDF
Deconstruction of complex protein signaling switches: a roadmap toward engineering higher‐order gene regulators
Published Online: Feb 09 2017
DOI: 10.1002/wnan.1461
Modular engineering of a hypothetical co‐repressor using components scavenged from the versatile LacI/GalR repressor family reviewed here
Abstract Full article on Wiley Online Library:   HTML | PDF

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Mauro Ferrari

Mauro Ferrari

started out in mechanical engineering and became interested in nanotechnology with his studies on nanomechanics and nanofluidics. His research work and involvement with setting up some of the premier nano centers and alliances in the world, bringing together universities, hospitals, and federal agencies, showcases interdisciplinarity at work.

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