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WIREs Syst Biol Med
Impact Factor: 3.542

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Wiley Interdisciplinary Reviews:
Systems Biology and Medicine
Volume 11 Issue 4 (July 2019)
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Towards multiscale modeling of the CD8+ T cell response to viral infections
Published Online: Feb 27 2019
DOI: 10.1002/wsbm.1446
Multiscale modeling of CD8+ T cell signaling, differentiation, and effector responses facilitate a quantitative understanding of viral infections and treatments.
Abstract Full article on Wiley Online Library:   HTML | PDF

Focus Articles

Recent advancement of light‐based single‐molecule approaches for studying biomolecules
Published Online: Feb 06 2019
DOI: 10.1002/wsbm.1445
Emerging techniques utilizing optical methods for single‐molecule studies.
Abstract Full article on Wiley Online Library:   HTML | PDF
Models of polymer physics for the architecture of the cell nucleus
Published Online: Dec 19 2018
DOI: 10.1002/wsbm.1444
Different molecular mechanisms shape chromosome folding. In one classical scenario contacts between distal DNA sites are established by bridging transcription factors. In another one, DNA extruding molecules produce loops. We discuss polymer physics models developed to describe such scenarios.
Abstract Full article on Wiley Online Library:   HTML | PDF

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