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WIREs Syst Biol Med
Impact Factor: 2.941

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Wiley Interdisciplinary Reviews:
Systems Biology and Medicine
Volume 5 Issue 3 (May/June 2013)
Page 257 - 390

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Hierarchical approaches for systems modeling in cardiac development
Published Online: Mar 05 2013
DOI: 10.1002/wsbm.1217
Abstract Full article on Wiley Online Library:   HTML | PDF
Engineered genetic information processing circuits
Published Online: Feb 26 2013
DOI: 10.1002/wsbm.1216
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Developing melanoma therapeutics: overview and update
Published Online: Feb 13 2013
DOI: 10.1002/wsbm.1210
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Advanced Reviews

Modeling cellular compartmentation in one‐carbon metabolism
Published Online: Feb 13 2013
DOI: 10.1002/wsbm.1209
Abstract Full article on Wiley Online Library:   HTML | PDF
Lower urinary tract development and disease
Published Online: Feb 13 2013
DOI: 10.1002/wsbm.1212
Abstract Full article on Wiley Online Library:   HTML | PDF
Bioimage informatics for understanding spatiotemporal dynamics of cellular processes
Published Online: Feb 13 2013
DOI: 10.1002/wsbm.1214
Abstract Full article on Wiley Online Library:   HTML | PDF

Focus Article

Mechano‐sensing and transduction by endothelial surface glycocalyx: composition, structure, and function
Published Online: Feb 07 2013
DOI: 10.1002/wsbm.1211
Abstract Full article on Wiley Online Library:   HTML | PDF

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In the Spotlight

Philip Benfey

Philip Benfey

Is intrigued by one of the key questions in developmental biology: how cells acquire their identities. This is an important question in human development, where stem cells divide and differentiate into skin, muscle, fat etc. It is equally central to plant development, where most organs and cells are formed from stem cell populations known as meristems. The Benfey lab addresses this question using a combination of genetics, molecular biology, and genomics to identify and characterize the genes that regulate formation of the root in the plant model system, Arabidopsis thaliana. The choice of the root as a model was based on the simplicity of its organization and its stereotyped developmental program.

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