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WIREs Syst Biol Med
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Wiley Interdisciplinary Reviews:
Systems Biology and Medicine
Volume 10 Issue 6 (November/December 2018)
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Cover Image, Volume 10, Issue 6
Published Online: Oct 18 2018
DOI: 10.1002/wsbm.1441
The cover image is based on Advanced Review Computational anatomy and diffeomorphometry: A dynamical systems model of neuroanatomy in the soft condensed matter continuum by Michael I. Miller et al., DOI: 10.1002/wsbm.1425.
Abstract Full article on Wiley Online Library:   HTML | PDF

Advanced Reviews

Cell cycle regulation of folate‐mediated one‐carbon metabolism
Published Online: Jun 11 2018
DOI: 10.1002/wsbm.1426
Individual enzymes within the FOCM network compete for limited folate cofactors. Cell cycle regulated‐expression, activity and cellular localization of enzymes and pathways in FOCM network enable cells to prioritize individual pathways within the network according to temporal needs. De novo purine and dTMP biosynthesis are regulated by cell cycle through both an increase in enzyme activity and formation of multienzyme complexes. Enzymes in dTMP biosynthesis pathway translocate in the nucleus and form complexes at sites of DNA replication.
Abstract Full article on Wiley Online Library:   HTML | PDF
Computational anatomy and diffeomorphometry: A dynamical systems model of neuroanatomy in the soft condensed matter continuum
Published Online: Jun 04 2018
DOI: 10.1002/wsbm.1425
Dynamics model in computational anatomy organized by force, acceleration, velocity, and displacement. The input term g represents energy derived forces from external measurements or internal energies of substructures. Images enter via the non‐linear observer.
Abstract Full article on Wiley Online Library:   HTML | PDF

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