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WIREs Syst Biol Med
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Wiley Interdisciplinary Reviews:
Systems Biology and Medicine
Volume 10 Issue 3 (May/June 2018)
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Overview

Image‐guided surgery in cancer: A strategy to reduce incidence of positive surgical margins
Published Online: Feb 23 2018
DOI: 10.1002/wsbm.1412
Schematic of surgical margins showing tumor present at the edge of resection (positive margins) or absence of tumor at the edge of resection (negative margins)
Abstract Full article on Wiley Online Library:   HTML | PDF

Advanced Reviews

Surveying the landscape of optogenetic methods for detection of protein–protein interactions
Published Online: Jan 15 2018
DOI: 10.1002/wsbm.1415
A survey of optogenetic methods for noninvasive detection and fluorescence visualization of protein–protein interactions in live cells and model organisms.
Abstract Full article on Wiley Online Library:   HTML | PDF
Human microbiota, blood group antigens, and disease
Published Online: Jan 09 2018
DOI: 10.1002/wsbm.1413
Abstract Full article on Wiley Online Library:   HTML | PDF

Focus Article

Piecing together cis ‐regulatory networks: insights from epigenomics studies in plants
Published Online: Nov 30 2017
DOI: 10.1002/wsbm.1411
Studies of plant genomes and epigenomes reveal the interdependence of genome context, DNA methylation state and gene expression patterns.
Abstract Full article on Wiley Online Library:   HTML | PDF

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In the Spotlight

Jens Nielsen

Jens Nielsen
is a Professor in the Department of Biology and Biological Engineering at Chalmers University of Technology in Göteborg, Sweden. His research focus is on systems biology of metabolism. The yeast Saccharomyces cerevisiae is the lab’s key organism for experimental research, but they also work with Aspergilli oryzae.

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