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WIREs Syst Biol Med
Impact Factor: 3.011
Wiley Interdisciplinary Reviews:
Systems Biology and Medicine
Volume 4 Issue 1 (January/February 2012)
Page 1 - 127

Opinion

Integrative physical oncology
Published Online: Aug 18 2011
DOI: 10.1002/wsbm.158
Abstract Full article on Wiley Online Library:   HTML | PDF

Overview

A systems biology approach to synovial joint lubrication in health, injury, and disease
Published Online: Aug 08 2011
DOI: 10.1002/wsbm.157
Abstract Full article on Wiley Online Library:   HTML | PDF

Advanced Reviews

Regulatory gene network circuits underlying T cell development from multipotent progenitors
Published Online: Oct 04 2011
DOI: 10.1002/wsbm.162
Abstract Full article on Wiley Online Library:   HTML | PDF
Normal morphogenesis of epithelial tissues and progression of epithelial tumors
Published Online: Sep 02 2011
DOI: 10.1002/wsbm.159
Abstract Full article on Wiley Online Library:   HTML | PDF
Stem cell genome‐to‐systems biology
Published Online: Apr 11 2011
DOI: 10.1002/wsbm.151
Abstract Full article on Wiley Online Library:   HTML | PDF

Focus Articles

Modeling of spatially‐restricted intracellular signaling
Published Online: Jul 15 2011
DOI: 10.1002/wsbm.155
Abstract Full article on Wiley Online Library:   HTML | PDF
Mechanistic modeling to investigate signaling by oncogenic Ras mutants
Published Online: Jul 15 2011
DOI: 10.1002/wsbm.156
Abstract Full article on Wiley Online Library:   HTML | PDF

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In the Spotlight

Blanche Capel

Blanche Capel

earned her Ph.D. at the University of Pennsylvania and has been at Duke University since 1993. She earned her endowed professorship, the James B. Duke Professor of Cell Biology, for the meaningful discoveries she has made since her postdoctoral work in genetics at the National Institute for Medical Research in London. The broad goal of the research in Dr. Capel’s laboratory is to characterize the cellular and molecular basis of morphogenesis – how the body forms. She uses gonadal (gender/sex) development in the mouse as her model system and investigates a gene she helped discover, Sry, the male sex determining gene. Gonad development is unique in that a single rudimentary tissue can be induced to form one of two different organs, an ovary or testis, and she is learning all she can about this central mystery of biology.

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