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WIREs Syst Biol Med
Impact Factor: 3.676
Wiley Interdisciplinary Reviews:
Systems Biology and Medicine
Volume 4 Issue 1 (January/February 2012)
Page 1 - 127

Opinion

Integrative physical oncology
Published Online: Aug 18 2011
DOI: 10.1002/wsbm.158
Abstract Full article on Wiley Online Library:   HTML | PDF

Overview

A systems biology approach to synovial joint lubrication in health, injury, and disease
Published Online: Aug 08 2011
DOI: 10.1002/wsbm.157
Abstract Full article on Wiley Online Library:   HTML | PDF

Advanced Reviews

Regulatory gene network circuits underlying T cell development from multipotent progenitors
Published Online: Oct 04 2011
DOI: 10.1002/wsbm.162
Abstract Full article on Wiley Online Library:   HTML | PDF
Normal morphogenesis of epithelial tissues and progression of epithelial tumors
Published Online: Sep 02 2011
DOI: 10.1002/wsbm.159
Abstract Full article on Wiley Online Library:   HTML | PDF
Stem cell genome‐to‐systems biology
Published Online: Apr 11 2011
DOI: 10.1002/wsbm.151
Abstract Full article on Wiley Online Library:   HTML | PDF

Focus Articles

Modeling of spatially‐restricted intracellular signaling
Published Online: Jul 15 2011
DOI: 10.1002/wsbm.155
Abstract Full article on Wiley Online Library:   HTML | PDF
Mechanistic modeling to investigate signaling by oncogenic Ras mutants
Published Online: Jul 15 2011
DOI: 10.1002/wsbm.156
Abstract Full article on Wiley Online Library:   HTML | PDF

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In the Spotlight

Alex Hoffmann

Alex Hoffmann

Dr. Hoffmann is Associate Professor of Signaling Systems Laboratory at UCSD. He moved to biology, tempted by the sense of discovery that he felt was missing as an undergraduate in Physics. During his graduate studies with Dr. Bob Roeder, he identified the genes that make up the transcription factor TFIID. Later on with Dr. David Baltimore, he sought to understand dynamic signaling pathways, realizing that his mathematical background may be relevant to study problems in a quantitative manner.

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