WIREs Syst Biol Med
WIREs Systems Biology & Medicine
- An important new forum to promote cross-disciplinary discussion of systems concepts in the life sciences and medicine
- An authoritative, encyclopedic resource addressing key topics from the perspectives of medicine, biology, physiology, computational biology and modeling, and bioengineering
- Now indexed by MEDLINE/PubMed, TRSI (formerly ISI), and Scopus
- Offers FREE downloadable PowerPoint presentations of figures for non-profit, educational use
Latest Articles
Opinions
- Systems biology of lung development and regeneration: current knowledge and recommendations for future research
- Pharmacogenomics discovery and implementation in genome‐wide association studies era
Overviews
- Cyclic nucleotide signaling in intestinal epithelia: getting to the gut of the matter
- Toward a quantitative understanding of the Wnt/ β ‐catenin pathway through simulation and experiment
Advanced Reviews
- Branched‐chain amino acid supplementation: impact on signaling and relevance to critical illness
- Systems biology of adipose tissue metabolism: regulation of growth, signaling and inflammation
Focus Articles
- Fatty acid oxidation: systems analysis and applications
- Riding the crest of the wave: parallels between the neural crest and cancer in epithelial‐to‐mesenchymal transition and migration
Editorial Commentaries
Featured Collection:
Top Ten WSBM Articles
Normal morphogenesis of epithelial tissues and progression of epithelial tumors
Advanced Review
Chun‐Chao Wang,Leen Jamal,Kevin A. Janes
Gut stem cells in tissue renewal and disease: methods, markers, and myths
Focus Article
Pamela Rizk,Nick Barker
Integrative physical oncology
Opinion
Haralampos Hatzikirou,Arnaud Chauviere,Amy L. Bauer,André Leier,Michael T. Lewis,Paul Macklin,Tatiana T. Marquez‐Lago,Elaine L. Bearer,Vittorio Cristini
Stem cell genome‐to‐systems biology
Advanced Review
Na‐Yu Chia,Huck‐Hui Ng
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the 9th annual conference in 2011.
In the Spotlight
Is intrigued by one of the key questions in developmental biology: how cells acquire their identities. This is an important question in human development, where stem cells divide and differentiate into skin, muscle, fat etc. It is equally central to plant development, where most organs and cells are formed from stem cell populations known as meristems. The Benfey lab addresses this question using a combination of genetics, molecular biology, and genomics to identify and characterize the genes that regulate formation of the root in the plant model system, Arabidopsis thaliana. The choice of the root as a model was based on the simplicity of its organization and its stereotyped developmental program.
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