Toxicology and Regulatory Issues in Nanomedicine

Emerging two‐dimensional monoelemental materials (Xenes): Fabrication, modification, and applications thereof in the field of bioimaging as nanocarriers

Advanced Review
Weijian Chen, Wanwan Pan, Jingwen Wang, Liang Cheng, Jing Wang, Lei Song, Yuan Hu, Xiaopeng Ma
Published Online: Aug 20 2021
DOI:10.1002/wnan.1750

Abstract Full article on Wiley Online Library: HTML | PDF

Endotoxin contamination in ovalbumin as viewed from a nano‐immunotherapy perspective

Perspective
Guibin Pang, Yun Liu, Yangyun Wang, Yong Wang, Fujun Wang, Jian Zhao, Leshuai W. Zhang
Published Online: Aug 10 2021
DOI:10.1002/wnan.1747

Abstract Full article on Wiley Online Library: HTML | PDF

Endotoxin contamination of engineered nanomaterials: Overcoming the hurdles associated with endotoxin testing

Advanced Review
Adriele Prina‐Mello, Gary Hannon
Published Online: Jul 13 2021
DOI:10.1002/wnan.1738

Abstract Full article on Wiley Online Library: HTML | PDF

In vitro dissolution considerations associated with nano drug delivery systems

Advanced Review
Ritu Gupta, Yuan Chen, Huan Xie
Published Online: Jun 16 2021
DOI:10.1002/wnan.1732

Abstract Full article on Wiley Online Library: HTML | PDF

The effects of gene × environment interactions on silver nanoparticle toxicity in the respiratory system: An adverse outcome pathway

Advanced Review
Tyler P. Nicholas, William K. Boyes, David K. Scoville, Tomomi W. Workman, Terrance J. Kavanagh, William A. Altemeier, Elaine M. Faustman
Published Online: Mar 25 2021
DOI:10.1002/wnan.1708

Abstract Full article on Wiley Online Library: HTML | PDF

Nanomaterials for Agricultural and Ecological Defense Applications: Active Agents and Sensors

Advanced Review
Pramila Sharma, Sanjay Kumar, Axita Patel, Bhaskar Datta, Robert K. DeLong
Published Online: Mar 21 2021
DOI:10.1002/wnan.1713

Abstract Full article on Wiley Online Library: HTML | PDF

Silver nanoparticles as a potential treatment against SARS‐CoV‐2: A review

Advanced Review
Fernanda Pilaquinga, Jeroni Morey, Marbel Torres, Rachid Seqqat, María de las Nieves Piña
Published Online: Feb 27 2021
DOI:10.1002/wnan.1707

Abstract Full article on Wiley Online Library: HTML | PDF

The evolution of polymer conjugation and drug targeting for the delivery of proteins and bioactive molecules

Advanced Review
Gianfranco Pasut, Elena Canato, Tommaso Tedeschini, Antonella Grigoletto
Published Online: Dec 14 2020
DOI:10.1002/wnan.1689

Abstract Full article on Wiley Online Library: HTML | PDF

Intracellular and extracellular targets as mechanisms of cancer therapy by nanomaterials in relation to their physicochemical properties

Advanced Review
Mary Gulumian, Charlene Andraos
Published Online: Oct 27 2020
DOI:10.1002/wnan.1680

Abstract Full article on Wiley Online Library: HTML | PDF

Challenges in the development of nanoparticle‐based imaging agents: Characterization and biology

Focus Article
Stephan T. Stern, Marina A. Dobrovolskaia, Jeffrey D. Clogston, Christina H. Liu, Siva Sai Krishna Dasa, Rachael M. Crist
Published Online: Aug 23 2020
DOI:10.1002/wnan.1665

Abstract Full article on Wiley Online Library: HTML | PDF

Nonclinical regulatory immunotoxicity testing of nanomedicinal products: Proposed strategy and possible pitfalls

Advanced Review
Christina Giannakou, Margriet V. D. Z. Park, Irene E. M. Bosselaers, Wim H. Jong, Jan Willem Laan, Henk Loveren, Rob J. Vandebriel, Robert E. Geertsma
Published Online: Apr 07 2020
DOI:10.1002/wnan.1633

Abstract Full article on Wiley Online Library: HTML | PDF

Impact of the protein corona on nanomaterial immune response and targeting ability

Advanced Review
Luca Digiacomo, Daniela Pozzi, Sara Palchetti, Alessandra Zingoni, Giulio Caracciolo
Published Online: Jan 30 2020
DOI:10.1002/wnan.1615

Abstract Full article on Wiley Online Library: HTML | PDF

Biocorona‐induced modifications in engineered nanomaterial–cellular interactions impacting biomedical applications

Focus Article
Lisa Kobos, Jonathan Shannahan
Published Online: Dec 01 2019
DOI:10.1002/wnan.1608

Abstract Full article on Wiley Online Library: HTML | PDF

The potential anti‐infective applications of metal oxide nanoparticles: A systematic review

Advanced Review
Yasmin Abo‐zeid, Gareth R. Williams
Published Online: Oct 08 2019
DOI:10.1002/wnan.1592

Abstract Full article on Wiley Online Library: HTML | PDF

The role of sex in particle‐induced inflammation and injury

Advanced Review
Jessica L. Ray, Paige Fletcher, Rachel Burmeister, Andrij Holian
Published Online: Sep 30 2019
DOI:10.1002/wnan.1589

Abstract Full article on Wiley Online Library: HTML | PDF

Integration of gadolinium in nanostructure for contrast enhanced‐magnetic resonance imaging

Advanced Review
Ramesh Marasini, Tuyen Duong Thanh Nguyen, Santosh Aryal
Published Online: Sep 05 2019
DOI:10.1002/wnan.1580

Abstract Full article on Wiley Online Library: HTML | PDF

National Cancer Institute Alliance for nanotechnology in cancer—Catalyzing research and translation toward novel cancer diagnostics and therapeutics

Overview
Christopher M. Hartshorn, Luisa M. Russell, Piotr Grodzinski
Published Online: Jul 01 2019
DOI:10.1002/wnan.1570

Abstract Full article on Wiley Online Library: HTML | PDF

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Article Type

Emerging two‐dimensional monoelemental materials (Xenes): Fabrication, modification, and applications thereof in the field of bioimaging as nanocarriers

Endotoxin contamination in ovalbumin as viewed from a nano‐immunotherapy perspective

Endotoxin contamination of engineered nanomaterials: Overcoming the hurdles associated with endotoxin testing

In vitro dissolution considerations associated with nano drug delivery systems

The effects of gene × environment interactions on silver nanoparticle toxicity in the respiratory system: An adverse outcome pathway

Nanomaterials for Agricultural and Ecological Defense Applications: Active Agents and Sensors

Silver nanoparticles as a potential treatment against SARS‐CoV‐2: A review

The evolution of polymer conjugation and drug targeting for the delivery of proteins and bioactive molecules

Intracellular and extracellular targets as mechanisms of cancer therapy by nanomaterials in relation to their physicochemical properties

Challenges in the development of nanoparticle‐based imaging agents: Characterization and biology

Nonclinical regulatory immunotoxicity testing of nanomedicinal products: Proposed strategy and possible pitfalls

Impact of the protein corona on nanomaterial immune response and targeting ability

Biocorona‐induced modifications in engineered nanomaterial–cellular interactions impacting biomedical applications

The potential anti‐infective applications of metal oxide nanoparticles: A systematic review

The role of sex in particle‐induced inflammation and injury

Integration of gadolinium in nanostructure for contrast enhanced‐magnetic resonance imaging

National Cancer Institute Alliance for nanotechnology in cancer—Catalyzing research and translation toward novel cancer diagnostics and therapeutics

The consolidation of nanomedicine

Overview of the blood compatibility of nanomedicines: A trend analysis of in vitro and in vivo studies

Protein crystal based materials for nanoscale applications in medicine and biotechnology

Mapping of the available standards against the regulatory needs for nanomedicines

Nanomaterial exposure, toxicity, and impact on human health

In vitro to in vivo benchmark dose comparisons to inform risk assessment of quantum dot nanomaterials

Mechanisms of carbon nanotube‐induced pulmonary fibrosis: a physicochemical characteristic perspective

Methodologies and approaches for the analysis of cell–nanoparticle interactions

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