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WIREs Syst Biol Med
Impact Factor: 4.192

Physiology

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Network dynamics: quantitative analysis of complex behavior in metabolism, organelles, and cells, from experiments to models and back

Advanced Review
Felix T. Kurz, Jackelyn M. Kembro, Ana G. Flesia, Antonis A. Armoundas, Sonia Cortassa, Miguel A. Aon, David Lloyd
Published Online: Sep 07 2016
DOI:10.1002/wsbm.1352

Abstract Full article on Wiley Online Library:   HTML | PDF
In silico bone mechanobiology: modeling a multifaceted biological system

Advanced Review
Mario Giorgi, Stefaan W. Verbruggen, Damien Lacroix
Published Online: Sep 07 2016
DOI:10.1002/wsbm.1356

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems physiology of the airways in health and obstructive pulmonary disease

Advanced Review
Jason H.T. Bates
Published Online: Jun 24 2016
DOI:10.1002/wsbm.1347

Abstract Full article on Wiley Online Library:   HTML | PDF
Mitochondrial metabolic remodeling in response to genetic and environmental perturbations

Advanced Review
Kate E.R. Hollinshead, Daniel A. Tennant
Published Online: May 19 2016
DOI:10.1002/wsbm.1334

Abstract Full article on Wiley Online Library:   HTML | PDF
Adaptive resistance to antibiotics in bacteria: a systems biology perspective

Advanced Review
Santiago Sandoval‐Motta, Maximino Aldana
Published Online: Apr 21 2016
DOI:10.1002/wsbm.1335

Abstract Full article on Wiley Online Library:   HTML | PDF
Signaling via the NFκB system

Advanced Review
Simon Mitchell, Jesse Vargas, Alexander Hoffmann
Published Online: Mar 16 2016
DOI:10.1002/wsbm.1331

Abstract Full article on Wiley Online Library:   HTML | PDF
Dynamics of the mammalian cell cycle in physiological and pathological conditions

Focus Article
Claude Gérard, Albert Goldbeter
Published Online: Nov 27 2015
DOI:10.1002/wsbm.1325

Abstract Full article on Wiley Online Library:   HTML | PDF
The virtual intestine: in silico modeling of small intestinal electrophysiology and motility and the applications

Advanced Review
Peng Du, Niranchan Paskaranandavadivel, Timothy R. Angeli, Leo K. Cheng, Gregory O'Grady
Published Online: Nov 12 2015
DOI:10.1002/wsbm.1324

Abstract Full article on Wiley Online Library:   HTML | PDF
Measurement and modeling of coronary blood flow

Overview
Matthew D. Sinclair, Jack Lee, Andrew N. Cookson, Simone Rivolo, Eoin R. Hyde, Nicolas P. Smith
Published Online: Jun 30 2015
DOI:10.1002/wsbm.1309

Abstract Full article on Wiley Online Library:   HTML | PDF
Implementation of integral feedback control in biological systems

Advanced Review
Pramod R. Somvanshi, Anilkumar K. Patel, Sharad Bhartiya, K. V. Venkatesh
Published Online: Jun 02 2015
DOI:10.1002/wsbm.1307

Abstract Full article on Wiley Online Library:   HTML | PDF
The role of the microbiota in ageing: current state and perspectives

Focus Article
Denise B. Lynch, Ian B. Jeffery, Paul W. O'Toole
Published Online: Mar 16 2015
DOI:10.1002/wsbm.1293

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems engineering meets quantitative systems pharmacology: from low‐level targets to engaging the host defenses

Opinion
Ioannis P. Androulakis
Published Online: Mar 16 2015
DOI:10.1002/wsbm.1294

Abstract Full article on Wiley Online Library:   HTML | PDF
Experience‐sensitive epigenetic mechanisms, developmental plasticity, and the biological embedding of chronic disease risk

Overview
Vincent T. Cunliffe
Published Online: Feb 20 2015
DOI:10.1002/wsbm.1291

Abstract Full article on Wiley Online Library:   HTML | PDF
Tactile sensory system: encoding from the periphery to the cortex

Focus Article
Lynette A. Jones, Allan M. Smith
Published Online: Mar 19 2014
DOI:10.1002/wsbm.1267

Abstract Full article on Wiley Online Library:   HTML | PDF
Apolipoprotein E receptor pathways in Alzheimer disease

Advanced Review
Vanessa Schmidt, Anne‐Sophie Carlo, Thomas E. Willnow
Published Online: Mar 06 2014
DOI:10.1002/wsbm.1262

Abstract Full article on Wiley Online Library:   HTML | PDF
Axes of differentiation in breast cancer: untangling stemness, lineage identity, and the epithelial to mesenchymal transition

Advanced Review
Roy Z. Granit, Michal Slyper, Ittai Ben‐Porath
Published Online: Nov 08 2013
DOI:10.1002/wsbm.1252

Abstract Full article on Wiley Online Library:   HTML | PDF
Integrative approaches for modeling regulation and function of the respiratory system

Overview
Alona Ben‐Tal, Merryn H. Tawhai
Published Online: Sep 09 2013
DOI:10.1002/wsbm.1244

Abstract Full article on Wiley Online Library:   HTML | PDF
Mathematical modeling of kidney transport

Advanced Review
Anita T. Layton
Published Online: Jul 12 2013
DOI:10.1002/wsbm.1232

Abstract Full article on Wiley Online Library:   HTML | PDF
Fatty acid oxidation: systems analysis and applications

Focus Article
Angela Cintolesi, María Rodríguez‐Moyá, Ramon Gonzalez
Published Online: May 09 2013
DOI:10.1002/wsbm.1226

Abstract Full article on Wiley Online Library:   HTML | PDF
Cyclic nucleotide signaling in intestinal epithelia: getting to the gut of the matter

Overview
Najla Arshad, Sandhya S. Visweswariah
Published Online: Apr 22 2013
DOI:10.1002/wsbm.1223

Abstract Full article on Wiley Online Library:   HTML | PDF
Branched‐chain amino acid supplementation: impact on signaling and relevance to critical illness

Advanced Review
John S. A. Mattick, Kubra Kamisoglu, Marianthi G. Ierapetritou, Ioannis P. Androulakis, Francois Berthiaume
Published Online: Mar 29 2013
DOI:10.1002/wsbm.1219

Abstract Full article on Wiley Online Library:   HTML | PDF
Modeling cellular compartmentation in one‐carbon metabolism

Advanced Review
Marco Scotti, Lorenzo Stella, Emily J. Shearer, Patrick J. Stover
Published Online: Feb 13 2013
DOI:10.1002/wsbm.1209

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of adipose tissue metabolism: regulation of growth, signaling and inflammation

Advanced Review
Sara Manteiga, Kyungoh Choi, Arul Jayaraman, Kyongbum Lee
Published Online: Feb 13 2013
DOI:10.1002/wsbm.1213

Abstract Full article on Wiley Online Library:   HTML | PDF
Mechano‐sensing and transduction by endothelial surface glycocalyx: composition, structure, and function

Focus Article
Bingmei M. Fu, John M. Tarbell
Published Online: Feb 07 2013
DOI:10.1002/wsbm.1211

Abstract Full article on Wiley Online Library:   HTML | PDF
Can a systems biology approach unlock the mysteries of Kawasaki disease?

Focus Article
Anne H. Rowley
Published Online: Jan 04 2013
DOI:10.1002/wsbm.1202

Abstract Full article on Wiley Online Library:   HTML | PDF
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