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WIREs Syst Biol Med
Impact Factor: 4.275

Biological Mechanisms

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Adaptive resistance to antibiotics in bacteria: a systems biology perspective

Advanced Review
Santiago Sandoval‐Motta, Maximino Aldana
Published Online: Apr 21 2016
DOI:10.1002/wsbm.1335

Abstract Full article on Wiley Online Library:   HTML | PDF
Signaling via the NFκB system

Advanced Review
Alexander Hoffmann, Jesse Vargas, Simon Mitchell
Published Online: Mar 16 2016
DOI:10.1002/wsbm.1331

Abstract Full article on Wiley Online Library:   HTML | PDF
Heart valve regeneration: the need for systems approaches

Focus Article
Jenna Usprech, Wen Li Kelly Chen, Craig A. Simmons
Published Online: Feb 09 2016
DOI:10.1002/wsbm.1329

Abstract Full article on Wiley Online Library:   HTML | PDF
Dynamics of the mammalian cell cycle in physiological and pathological conditions

Focus Article
Claude Gérard, Albert Goldbeter
Published Online: Nov 27 2015
DOI:10.1002/wsbm.1325

Abstract Full article on Wiley Online Library:   HTML | PDF
Modeling calcium regulation of contraction, energetics, signaling, and transcription in the cardiac myocyte

Advanced Review
Raimond L. Winslow, Mark A. Walker, Joseph L. Greenstein
Published Online: Nov 12 2015
DOI:10.1002/wsbm.1322

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology approaches for identifying adverse drug reactions and elucidating their underlying biological mechanisms

Advanced Review
Mary Regina Boland, Alexandra Jacunski, Tal Lorberbaum, Joseph D. Romano, Robert Moskovitch, Nicholas P. Tatonetti
Published Online: Nov 12 2015
DOI:10.1002/wsbm.1323

Abstract Full article on Wiley Online Library:   HTML | PDF
In search for symmetries in the metabolism of cancer

Advanced Review
Francesco Gatto, Jens Nielsen
Published Online: Nov 05 2015
DOI:10.1002/wsbm.1321

Abstract Full article on Wiley Online Library:   HTML | PDF
The macrophage and its role in inflammation and tissue repair: mathematical and systems biology approaches

Focus Article
Joanne L. Dunster
Published Online: Oct 13 2015
DOI:10.1002/wsbm.1320

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems analysis of host–parasite interactions

Advanced Review
Justine Swann, Neema Jamshidi, Nathan E. Lewis, Elizabeth A. Winzeler
Published Online: Aug 26 2015
DOI:10.1002/wsbm.1311

Abstract Full article on Wiley Online Library:   HTML | PDF
Metabolic network modeling of microbial communities

Advanced Review
Matthew B. Biggs, Gregory L. Medlock, Glynis L. Kolling, Jason A. Papin
Published Online: Jun 24 2015
DOI:10.1002/wsbm.1308

Abstract Full article on Wiley Online Library:   HTML | PDF
Implementation of integral feedback control in biological systems

Advanced Review
Pramod R. Somvanshi, Anilkumar K. Patel, Sharad Bhartiya, K. V. Venkatesh
Published Online: Jun 02 2015
DOI:10.1002/wsbm.1307

Abstract Full article on Wiley Online Library:   HTML | PDF
Topology, dynamics, and heterogeneity in immune signaling

Advanced Review
J. Taylor Webb, Marcelo Behar
Published Online: May 27 2015
DOI:10.1002/wsbm.1306

Abstract Full article on Wiley Online Library:   HTML | PDF
The cell as the mechanistic basis for evolution

Advanced Review
J.S. Torday
Published Online: May 25 2015
DOI:10.1002/wsbm.1305

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of host–microbe metabolomics

Advanced Review
Almut Heinken, Ines Thiele
Published Online: Apr 30 2015
DOI:10.1002/wsbm.1301

Abstract Full article on Wiley Online Library:   HTML | PDF
Integration of systems glycobiology with bioinformatics toolboxes, glycoinformatics resources, and glycoproteomics data

Advanced Review
Gang Liu, Sriram Neelamegham
Published Online: Apr 13 2015
DOI:10.1002/wsbm.1296

Abstract Full article on Wiley Online Library:   HTML | PDF
Experience‐sensitive epigenetic mechanisms, developmental plasticity, and the biological embedding of chronic disease risk

Overview
Vincent T. Cunliffe
Published Online: Feb 20 2015
DOI:10.1002/wsbm.1291

Abstract Full article on Wiley Online Library:   HTML | PDF
A systems view of epigenetic networks regulating pancreas development and β‐cell function

Opinion
Ruiyu Xie, Andrea C. Carrano, Maike Sander
Published Online: Jan 27 2015
DOI:10.1002/wsbm.1287

Abstract Full article on Wiley Online Library:   HTML | PDF
Integrating omics into the cardiac differentiation of human pluripotent stem cells

Focus Article
Agustin Rojas‐Muñoz, Mano R. Maurya, Frederick Lo, Erik Willems
Published Online: Aug 08 2014
DOI:10.1002/wsbm.1268

Abstract Full article on Wiley Online Library:   HTML | PDF
Large scale molecular simulations of nanotoxicity

Focus Article
Camilo A. Jimenez‐Cruz, Seung‐gu Kang, Ruhong Zhou
Published Online: Aug 08 2014
DOI:10.1002/wsbm.1271

Abstract Full article on Wiley Online Library:   HTML | PDF
Boolean modeling: a logic‐based dynamic approach for understanding signaling and regulatory networks and for making useful predictions

Overview
Réka Albert, Juilee Thakar
Published Online: Jul 15 2014
DOI:10.1002/wsbm.1273

Abstract Full article on Wiley Online Library:   HTML | PDF
Drug discovery and the maze of biological complexity: an editorial essay

Editorial Commentary
Shankar Subramaniam
Published Online: Mar 19 2014
DOI:10.1002/wsbm.1266

Abstract Full article on Wiley Online Library:   HTML | PDF
Signaling networks in palate development

Focus Article
Jamie Lane, Vesa Kaartinen
Published Online: Mar 18 2014
DOI:10.1002/wsbm.1265

Abstract Full article on Wiley Online Library:   HTML | PDF
Modeling the intracellular organization of calcium signaling

Advanced Review
Geneviève Dupont
Published Online: Mar 06 2014
DOI:10.1002/wsbm.1261

Abstract Full article on Wiley Online Library:   HTML | PDF
Apolipoprotein E receptor pathways in Alzheimer disease

Advanced Review
Vanessa Schmidt, Anne‐Sophie Carlo, Thomas E. Willnow
Published Online: Mar 06 2014
DOI:10.1002/wsbm.1262

Abstract Full article on Wiley Online Library:   HTML | PDF
Genome network medicine: innovation to overcome huge challenges in cancer therapy

Focus Article
Dimitrios H. Roukos
Published Online: Dec 06 2013
DOI:10.1002/wsbm.1254

Abstract Full article on Wiley Online Library:   HTML | PDF
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