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WIREs Syst Biol Med
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Models of Systems Properties and Processes

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Multiscale modeling of vertebrate limb development

Advanced Review
Tilmann Glimm, Ramray Bhat, Stuart A. Newman
Published Online: Mar 25 2020
DOI:10.1002/wsbm.1485

Abstract Full article on Wiley Online Library:   HTML | PDF
Aspirin and the chemoprevention of cancers: A mathematical and evolutionary dynamics perspective

Advanced Review
Natalia L. Komarova, C. Richard Boland, Ajay Goel, Dominik Wodarz
Published Online: Mar 12 2020
DOI:10.1002/wsbm.1487

Abstract Full article on Wiley Online Library:   HTML | PDF
Modeling immune cell behavior across scales in cancer

Advanced Review
Stacey D. Finley, Colin G. Cess, Sahak Z. Makaryan
Published Online: Mar 04 2020
DOI:10.1002/wsbm.1484

Abstract Full article on Wiley Online Library:   HTML | PDF
Calibration of ionic and cellular cardiac electrophysiology models

Advanced Review
Dominic G. Whittaker, Michael Clerx, Chon Lok Lei, David J. Christini, Gary R. Mirams
Published Online: Feb 21 2020
DOI:10.1002/wsbm.1482

Abstract Full article on Wiley Online Library:   HTML | PDF
Intracellular signaling dynamics and their role in coordinating tissue repair

Focus Article
Allyson E. Sgro, Breanna M. O'Reilly, Samuel J. Ghilardi
Published Online: Feb 08 2020
DOI:10.1002/wsbm.1479

Abstract Full article on Wiley Online Library:   HTML | PDF
Cholesterol interaction motifs in G protein‐coupled receptors: Slippery hot spots?

Advanced Review
Parijat Sarkar, Amitabha Chattopadhyay
Published Online: Feb 07 2020
DOI:10.1002/wsbm.1481

Abstract Full article on Wiley Online Library:   HTML | PDF
How personalized heart modeling can help treatment of lethal arrhythmias: A focus on ventricular tachycardia ablation strategies in post‐infarction patients

Advanced Review
Natalia A. Trayanova, Ashish N. Doshi, Adityo Prakosa
Published Online: Jan 09 2020
DOI:10.1002/wsbm.1477

Abstract Full article on Wiley Online Library:   HTML | PDF
Growth control in the Drosophila wing disk

Advanced Review
Hans G. Othmer, Jay A. Stotsky, Jia Gou
Published Online: Jan 09 2020
DOI:10.1002/wsbm.1478

Abstract Full article on Wiley Online Library:   HTML | PDF
Theory of cell fate

Primer
Michael J. Casey, Patrick S. Stumpf, Ben D. MacArthur
Published Online: Dec 12 2019
DOI:10.1002/wsbm.1471

Abstract Full article on Wiley Online Library:   HTML | PDF
Exploring cardiac form and function: A length‐scale computational biology approach

Advanced Review
William F. Sherman, Anna Grosberg
Published Online: Dec 02 2019
DOI:10.1002/wsbm.1470

Abstract Full article on Wiley Online Library:   HTML | PDF
Network architecture and regulatory logic in neural crest development

Focus Article
Austin S. Hovland, Megan Rothstein, Marcos Simoes‐Costa
Published Online: Nov 08 2019
DOI:10.1002/wsbm.1468

Abstract Full article on Wiley Online Library:   HTML | PDF
Skeletal muscle: A review of molecular structure and function, in health and disease

Advanced Review
Kavitha Mukund, Shankar Subramaniam
Published Online: Aug 13 2019
DOI:10.1002/wsbm.1462

Abstract Full article on Wiley Online Library:   HTML | PDF
Hybrid modeling frameworks of tumor development and treatment

UPDATE
Ibrahim M. Chamseddine, Katarzyna A. Rejniak
Published Online: Jul 17 2019
DOI:10.1002/wsbm.1461

Abstract Full article on Wiley Online Library:   HTML | PDF
Stochastic simulation algorithms for computational systems biology: Exact, approximate, and hybrid methods

Advanced Review
Luca Marchetti, Corrado Priami, Federico Reali, Giulia Simoni
Published Online: Jul 01 2019
DOI:10.1002/wsbm.1459

Abstract Full article on Wiley Online Library:   HTML | PDF
Agent‐based models of inflammation in translational systems biology: A decade later

UPDATE
Yoram Vodovotz, Gary An
Published Online: Jul 01 2019
DOI:10.1002/wsbm.1460

Abstract Full article on Wiley Online Library:   HTML | PDF
Multiscale modeling of the neuromuscular system: Coupling neurophysiology and skeletal muscle mechanics

Advanced Review
Oliver Röhrle, Utku Ş. Yavuz, Thomas Klotz, Francesco Negro, Thomas Heidlauf
Published Online: Jun 24 2019
DOI:10.1002/wsbm.1457

Abstract Full article on Wiley Online Library:   HTML | PDF
IL7 receptor signaling in T cells: A mathematical modeling perspective

Overview
Jung‐Hyun Park, Adam T. Waickman, Joseph Reynolds, Mario Castro, Carmen Molina‐París
Published Online: May 28 2019
DOI:10.1002/wsbm.1447

Abstract Full article on Wiley Online Library:   HTML | PDF
Essential contributions of enhancer genomic regulatory elements to microglial cell identity and functions

Focus Article
André Machado Xavier, Sarah Belhocine, David Gosselin
Published Online: Apr 23 2019
DOI:10.1002/wsbm.1449

Abstract Full article on Wiley Online Library:   HTML | PDF
Calcium signals that determine vascular resistance

Focus Article
Matteo Ottolini, Kwangseok Hong, Swapnil K. Sonkusare
Published Online: Mar 18 2019
DOI:10.1002/wsbm.1448

Abstract Full article on Wiley Online Library:   HTML | PDF
Towards multiscale modeling of the CD8+ T cell response to viral infections

Advanced Review
Subhasish Baral, Rubesh Raja, Pramita Sen, Narendra M. Dixit
Published Online: Feb 27 2019
DOI:10.1002/wsbm.1446

Abstract Full article on Wiley Online Library:   HTML | PDF
Integrating molecular networks with genetic variant interpretation for precision medicine

Overview
Hannah Carter, Kivilcim Ozturk, Emidio Capriotti
Published Online: Dec 12 2018
DOI:10.1002/wsbm.1443

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of robustness and homeostatic mechanisms

Overview
H. Frederik Nijhout, Janet A. Best, Michael C. Reed
Published Online: Oct 29 2018
DOI:10.1002/wsbm.1440

Abstract Full article on Wiley Online Library:   HTML | PDF
Mathematical modeling of circadian rhythms

Focus Article
Ameneh Asgari‐Targhi, Elizabeth B. Klerman
Published Online: Oct 17 2018
DOI:10.1002/wsbm.1439

Abstract Full article on Wiley Online Library:   HTML | PDF
Context‐dependent regulation of receptor tyrosine kinases: Insights from systems biology approaches

Focus Article
Inez Lam, Christina M. Pickering, Feilim Mac Gabhann
Published Online: Sep 26 2018
DOI:10.1002/wsbm.1437

Abstract Full article on Wiley Online Library:   HTML | PDF
The mammalian mycobiome: A complex system in a dynamic relationship with the host

Advanced Review
Ghee Chuan Lai, Tze Guan Tan, Norman Pavelka
Published Online: Sep 25 2018
DOI:10.1002/wsbm.1438

Abstract Full article on Wiley Online Library:   HTML | PDF
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