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WIREs Syst Biol Med
Impact Factor: 3.542

Models of Systems Properties and Processes

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Mathematical modeling of kidney transport

Advanced Review
Anita T. Layton
Published Online: Jul 12 2013
DOI:10.1002/wsbm.1232

Abstract Full article on Wiley Online Library:   HTML | PDF
Multiscale image‐based modeling and simulation of gas flow and particle transport in the human lungs

Focus Article
Ching‐Long Lin, Merryn H. Tawhai, Eric A. Hoffman
Published Online: Jul 10 2013
DOI:10.1002/wsbm.1234

Abstract Full article on Wiley Online Library:   HTML | PDF
Computational and experimental characterization of skin mechanics: identifying current challenges and future directions

Advanced Review
Jessica W.Y. Jor, Matthew D. Parker, Andrew J. Taberner, Martyn P. Nash, Poul M.F. Nielsen
Published Online: Jun 11 2013
DOI:10.1002/wsbm.1228

Abstract Full article on Wiley Online Library:   HTML | PDF
A conceptual framework for computational models of Achilles tendon homeostasis

Advanced Review
David W. Smith, Jonas Rubenson, David Lloyd, Minghao Zheng, Justin Fernandez, Thor Besier, Jiake Xu, Bruce S. Gardiner
Published Online: Jun 11 2013
DOI:10.1002/wsbm.1229

Abstract Full article on Wiley Online Library:   HTML | PDF
Excitable behavior in amoeboid chemotaxis

Focus Article
Changji Shi, Pablo A. Iglesias
Published Online: Jun 11 2013
DOI:10.1002/wsbm.1230

Abstract Full article on Wiley Online Library:   HTML | PDF
Agent‐based modeling: a systematic assessment of use cases and requirements for enhancing pharmaceutical research and development productivity

Advanced Review
C. Anthony Hunt, Ryan C. Kennedy, Sean H. J. Kim, Glen E. P. Ropella
Published Online: Jun 04 2013
DOI:10.1002/wsbm.1222

Abstract Full article on Wiley Online Library:   HTML | PDF
Mathematical modeling of folate metabolism

Focus Article
John C. Panetta, Steven W. Paugh, William E. Evans
Published Online: May 22 2013
DOI:10.1002/wsbm.1227

Abstract Full article on Wiley Online Library:   HTML | PDF
How changes in fibril‐level organization correlate with the macrolevel behavior of articular cartilage

Focus Article
Mieke Nickien, Ashvin Thambyah, Neil Broom
Published Online: Apr 01 2013
DOI:10.1002/wsbm.1220

Abstract Full article on Wiley Online Library:   HTML | PDF
Toward a quantitative understanding of the Wnt/β‐catenin pathway through simulation and experiment

Overview
Bethan Lloyd‐Lewis, Alexander G. Fletcher, Trevor C. Dale, Helen M. Byrne
Published Online: Mar 29 2013
DOI:10.1002/wsbm.1221

Abstract Full article on Wiley Online Library:   HTML | PDF
Toward the virtual stomach: progress in multiscale modeling of gastric electrophysiology and motility

Focus Article
Peng Du, Gregory O'Grady, Jerry Gao, Shameer Sathar, Leo K. Cheng
Published Online: Mar 05 2013
DOI:10.1002/wsbm.1218

Abstract Full article on Wiley Online Library:   HTML | PDF
Hierarchical approaches for systems modeling in cardiac development

Overview
Russell A. Gould, Lina M. Aboulmouna, Jeffrey D. Varner, Jonathan T. Butcher
Published Online: Mar 05 2013
DOI:10.1002/wsbm.1217

Abstract Full article on Wiley Online Library:   HTML | PDF
Engineered genetic information processing circuits

Overview
Hao Qi, Andrew Blanchard, Ting Lu
Published Online: Feb 26 2013
DOI:10.1002/wsbm.1216

Abstract Full article on Wiley Online Library:   HTML | PDF
Mechano‐sensing and transduction by endothelial surface glycocalyx: composition, structure, and function

Focus Article
Bingmei M. Fu, John M. Tarbell
Published Online: Feb 07 2013
DOI:10.1002/wsbm.1211

Abstract Full article on Wiley Online Library:   HTML | PDF
β‐Arrestin‐kinase scaffolds: turn them on or turn them off?

Focus Article
Alice Lin, Kathryn A. DeFea
Published Online: Jan 14 2013
DOI:10.1002/wsbm.1203

Abstract Full article on Wiley Online Library:   HTML | PDF
Model‐based design of experiments for cellular processes

Advanced Review
Ann E. Rundell, Gregery T. Buzzard, Ankush Chakrabarty
Published Online: Jan 04 2013
DOI:10.1002/wsbm.1204

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of lung development and regeneration: current knowledge and recommendations for future research

Opinion
James S. Hagood, Namasivayam Ambalavanan
Published Online: Jan 04 2013
DOI:10.1002/wsbm.1205

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems analysis of biological networks in skeletal muscle function

Advanced Review
Lucas R. Smith, Gretchen Meyer, Richard L. Lieber
Published Online: Nov 27 2012
DOI:10.1002/wsbm.1197

Abstract Full article on Wiley Online Library:   HTML | PDF
Accelerating cancer systems biology research through Semantic Web technology

Overview
Thomas S. Deisboeck, Patrick Shironoshita, Thomas Taylor, Jonathan Sagotsky, Zhihui Wang
Published Online: Nov 27 2012
DOI:10.1002/wsbm.1200

Abstract Full article on Wiley Online Library:   HTML | PDF
Stem cell bioengineering at the interface of systems‐based models and high‐throughput platforms

Overview
Gregory H. Underhill
Published Online: Aug 23 2012
DOI:10.1002/wsbm.1189

Abstract Full article on Wiley Online Library:   HTML | PDF
Large‐scale mouse knockouts and phenotypes

Advanced Review
Joanna Bottomley, Jacqueline K. White, Richard Houghton, Edward Ryder, Ramiro Ramírez‐Solis
Published Online: Aug 15 2012
DOI:10.1002/wsbm.1183

Abstract Full article on Wiley Online Library:   HTML | PDF
Post‐translational modification: nature's escape from genetic imprisonment and the basis for dynamic information encoding

Advanced Review
Sudhakaran Prabakaran, Guy Lippens, Hanno Steen, Jeremy Gunawardena
Published Online: Aug 15 2012
DOI:10.1002/wsbm.1185

Abstract Full article on Wiley Online Library:   HTML | PDF
From base pair to bedside: molecular simulation and the translation of genomics to personalized medicine

Advanced Review
David W. Wright, Shunzhou Wan, Nour Shublaq, Stefan J. Zasada, Peter V. Coveney
Published Online: Aug 15 2012
DOI:10.1002/wsbm.1186

Abstract Full article on Wiley Online Library:   HTML | PDF
Mitochondrial network energetics in the heart

Advanced Review
Miguel A. Aon, Sonia Cortassa
Published Online: Aug 15 2012
DOI:10.1002/wsbm.1188

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of skeletal muscle: fiber type as an organizing principle

Advanced Review
Sarah M. Greising, Heather M. Gransee, Carlos B. Mantilla, Gary C. Sieck
Published Online: Jul 18 2012
DOI:10.1002/wsbm.1184

Abstract Full article on Wiley Online Library:   HTML | PDF
Decoding the functions of post‐transcriptional regulators in the determination of inflammatory states: focus on macrophage activation

Focus Article
Panagiota Kafasla, Ioannis Karakasiliotis, Dimitris L. Kontoyiannis
Published Online: Jul 03 2012
DOI:10.1002/wsbm.1179

Abstract Full article on Wiley Online Library:   HTML | PDF
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