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WIREs Syst Biol Med
Impact Factor: 3.542

Models of Systems Properties and Processes

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Tactile sensory system: encoding from the periphery to the cortex

Focus Article
Lynette A. Jones, Allan M. Smith
Published Online: Mar 19 2014
DOI:10.1002/wsbm.1267

Abstract Full article on Wiley Online Library:   HTML | PDF
Signaling networks in palate development

Focus Article
Jamie Lane, Vesa Kaartinen
Published Online: Mar 18 2014
DOI:10.1002/wsbm.1265

Abstract Full article on Wiley Online Library:   HTML | PDF
Modeling the intracellular organization of calcium signaling

Advanced Review
Geneviève Dupont
Published Online: Mar 06 2014
DOI:10.1002/wsbm.1261

Abstract Full article on Wiley Online Library:   HTML | PDF
Apolipoprotein E receptor pathways in Alzheimer disease

Advanced Review
Vanessa Schmidt, Anne‐Sophie Carlo, Thomas E. Willnow
Published Online: Mar 06 2014
DOI:10.1002/wsbm.1262

Abstract Full article on Wiley Online Library:   HTML | PDF
Personalizing oncology treatments by predicting drug efficacy, side‐effects, and improved therapy: mathematics, statistics, and their integration

Advanced Review
Zvia Agur, Moran Elishmereni, Yuri Kheifetz
Published Online: Mar 06 2014
DOI:10.1002/wsbm.1263

Abstract Full article on Wiley Online Library:   HTML | PDF
Glass‐like dynamics in the cell and in cellular collectives

Advanced Review
Monirosadat Sadati, Amir Nourhani, Jeffrey J. Fredberg, Nader Taheri Qazvini
Published Online: Jan 15 2014
DOI:10.1002/wsbm.1258

Abstract Full article on Wiley Online Library:   HTML | PDF
Advances in modeling ventricular arrhythmias: from mechanisms to the clinic

Focus Article
Natalia A. Trayanova, Patrick M. Boyle
Published Online: Dec 06 2013
DOI:10.1002/wsbm.1256

Abstract Full article on Wiley Online Library:   HTML | PDF
The structure of dynamic GPCR signaling networks

Focus Article
Patrick R. O'Neill, Lopamudra Giri, W. K. Ajith Karunarathne, Anilkumar K. Patel, K. V. Venkatesh, N. Gautam
Published Online: Nov 08 2013
DOI:10.1002/wsbm.1249

Abstract Full article on Wiley Online Library:   HTML | PDF
Rule‐based modeling: a computational approach for studying biomolecular site dynamics in cell signaling systems

Overview
Lily A. Chylek, Leonard A. Harris, Chang‐Shung Tung, James R. Faeder, Carlos F. Lopez, William S. Hlavacek
Published Online: Sep 30 2013
DOI:10.1002/wsbm.1245

Abstract Full article on Wiley Online Library:   HTML | PDF
Molecular mechanisms underlying neuronal synaptic plasticity: systems biology meets computational neuroscience in the wilds of synaptic plasticity

Advanced Review
Kim T. Blackwell, Joanna Jedrzejewska‐Szmek
Published Online: Sep 09 2013
DOI:10.1002/wsbm.1240

Abstract Full article on Wiley Online Library:   HTML | PDF
Integrative approaches for modeling regulation and function of the respiratory system

Overview
Alona Ben‐Tal, Merryn H. Tawhai
Published Online: Sep 09 2013
DOI:10.1002/wsbm.1244

Abstract Full article on Wiley Online Library:   HTML | PDF
Computational approaches for understanding energy metabolism

Focus Article
Alexander A. Shestov, Brandon Barker, Zhenglong Gu, Jason W. Locasale
Published Online: Jul 29 2013
DOI:10.1002/wsbm.1238

Abstract Full article on Wiley Online Library:   HTML | PDF
Endothelial cell motility, coordination and pattern formation during vasculogenesis

Advanced Review
Andras Czirok
Published Online: Jul 15 2013
DOI:10.1002/wsbm.1233

Abstract Full article on Wiley Online Library:   HTML | PDF
Mathematical modeling of kidney transport

Advanced Review
Anita T. Layton
Published Online: Jul 12 2013
DOI:10.1002/wsbm.1232

Abstract Full article on Wiley Online Library:   HTML | PDF
Multiscale image‐based modeling and simulation of gas flow and particle transport in the human lungs

Focus Article
Ching‐Long Lin, Merryn H. Tawhai, Eric A. Hoffman
Published Online: Jul 10 2013
DOI:10.1002/wsbm.1234

Abstract Full article on Wiley Online Library:   HTML | PDF
Computational and experimental characterization of skin mechanics: identifying current challenges and future directions

Advanced Review
Jessica W.Y. Jor, Matthew D. Parker, Andrew J. Taberner, Martyn P. Nash, Poul M.F. Nielsen
Published Online: Jun 11 2013
DOI:10.1002/wsbm.1228

Abstract Full article on Wiley Online Library:   HTML | PDF
A conceptual framework for computational models of Achilles tendon homeostasis

Advanced Review
David W. Smith, Jonas Rubenson, David Lloyd, Minghao Zheng, Justin Fernandez, Thor Besier, Jiake Xu, Bruce S. Gardiner
Published Online: Jun 11 2013
DOI:10.1002/wsbm.1229

Abstract Full article on Wiley Online Library:   HTML | PDF
Excitable behavior in amoeboid chemotaxis

Focus Article
Changji Shi, Pablo A. Iglesias
Published Online: Jun 11 2013
DOI:10.1002/wsbm.1230

Abstract Full article on Wiley Online Library:   HTML | PDF
Agent‐based modeling: a systematic assessment of use cases and requirements for enhancing pharmaceutical research and development productivity

Advanced Review
C. Anthony Hunt, Ryan C. Kennedy, Sean H. J. Kim, Glen E. P. Ropella
Published Online: Jun 04 2013
DOI:10.1002/wsbm.1222

Abstract Full article on Wiley Online Library:   HTML | PDF
Mathematical modeling of folate metabolism

Focus Article
John C. Panetta, Steven W. Paugh, William E. Evans
Published Online: May 22 2013
DOI:10.1002/wsbm.1227

Abstract Full article on Wiley Online Library:   HTML | PDF
How changes in fibril‐level organization correlate with the macrolevel behavior of articular cartilage

Focus Article
Mieke Nickien, Ashvin Thambyah, Neil Broom
Published Online: Apr 01 2013
DOI:10.1002/wsbm.1220

Abstract Full article on Wiley Online Library:   HTML | PDF
Toward a quantitative understanding of the Wnt/β‐catenin pathway through simulation and experiment

Overview
Bethan Lloyd‐Lewis, Alexander G. Fletcher, Trevor C. Dale, Helen M. Byrne
Published Online: Mar 29 2013
DOI:10.1002/wsbm.1221

Abstract Full article on Wiley Online Library:   HTML | PDF
Toward the virtual stomach: progress in multiscale modeling of gastric electrophysiology and motility

Focus Article
Peng Du, Gregory O'Grady, Jerry Gao, Shameer Sathar, Leo K. Cheng
Published Online: Mar 05 2013
DOI:10.1002/wsbm.1218

Abstract Full article on Wiley Online Library:   HTML | PDF
Hierarchical approaches for systems modeling in cardiac development

Overview
Russell A. Gould, Lina M. Aboulmouna, Jeffrey D. Varner, Jonathan T. Butcher
Published Online: Mar 05 2013
DOI:10.1002/wsbm.1217

Abstract Full article on Wiley Online Library:   HTML | PDF
Engineered genetic information processing circuits

Overview
Hao Qi, Andrew Blanchard, Ting Lu
Published Online: Feb 26 2013
DOI:10.1002/wsbm.1216

Abstract Full article on Wiley Online Library:   HTML | PDF
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