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Analytical and Computational Methods

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Multiscale modeling of vertebrate limb development

Advanced Review
Tilmann Glimm, Ramray Bhat, Stuart A. Newman
Published Online: Mar 25 2020
DOI:10.1002/wsbm.1485

Abstract Full article on Wiley Online Library:   HTML | PDF
Computational models to explore the complexity of the epithelial to mesenchymal transition in cancer

Focus Article
Marilisa Cortesi, Chiara Liverani, Laura Mercatali, Toni Ibrahim, Emanuele Giordano
Published Online: Mar 24 2020
DOI:10.1002/wsbm.1488

Abstract Full article on Wiley Online Library:   HTML | PDF
Aspirin and the chemoprevention of cancers: A mathematical and evolutionary dynamics perspective

Advanced Review
Natalia L. Komarova, C. Richard Boland, Ajay Goel, Dominik Wodarz
Published Online: Mar 12 2020
DOI:10.1002/wsbm.1487

Abstract Full article on Wiley Online Library:   HTML | PDF
Calibration of ionic and cellular cardiac electrophysiology models

Advanced Review
Dominic G. Whittaker, Michael Clerx, Chon Lok Lei, David J. Christini, Gary R. Mirams
Published Online: Feb 21 2020
DOI:10.1002/wsbm.1482

Abstract Full article on Wiley Online Library:   HTML | PDF
Cholesterol interaction motifs in G protein‐coupled receptors: Slippery hot spots?

Advanced Review
Parijat Sarkar, Amitabha Chattopadhyay
Published Online: Feb 07 2020
DOI:10.1002/wsbm.1481

Abstract Full article on Wiley Online Library:   HTML | PDF
How personalized heart modeling can help treatment of lethal arrhythmias: A focus on ventricular tachycardia ablation strategies in post‐infarction patients

Advanced Review
Natalia A. Trayanova, Ashish N. Doshi, Adityo Prakosa
Published Online: Jan 09 2020
DOI:10.1002/wsbm.1477

Abstract Full article on Wiley Online Library:   HTML | PDF
Applications of stable isotope‐based metabolomics and fluxomics toward synthetic biology of cyanobacteria

Advanced Review
Jamey D. Young, Piyoosh Kumar Babele
Published Online: Dec 09 2019
DOI:10.1002/wsbm.1472

Abstract Full article on Wiley Online Library:   HTML | PDF
Lipidomics: Current state of the art in a fast moving field

Focus Article
Valerie B. O'Donnell, Kim Ekroos, Gerhard Liebisch, Michael Wakelam
Published Online: Oct 23 2019
DOI:10.1002/wsbm.1466

Abstract Full article on Wiley Online Library:   HTML | PDF
Hybrid modeling frameworks of tumor development and treatment

UPDATE
Ibrahim M. Chamseddine, Katarzyna A. Rejniak
Published Online: Jul 17 2019
DOI:10.1002/wsbm.1461

Abstract Full article on Wiley Online Library:   HTML | PDF
Stochastic simulation algorithms for computational systems biology: Exact, approximate, and hybrid methods

Advanced Review
Luca Marchetti, Corrado Priami, Federico Reali, Giulia Simoni
Published Online: Jul 01 2019
DOI:10.1002/wsbm.1459

Abstract Full article on Wiley Online Library:   HTML | PDF
Multiscale modeling of the neuromuscular system: Coupling neurophysiology and skeletal muscle mechanics

Advanced Review
Oliver Röhrle, Utku Ş. Yavuz, Thomas Klotz, Francesco Negro, Thomas Heidlauf
Published Online: Jun 24 2019
DOI:10.1002/wsbm.1457

Abstract Full article on Wiley Online Library:   HTML | PDF
IL7 receptor signaling in T cells: A mathematical modeling perspective

Overview
Jung‐Hyun Park, Adam T. Waickman, Joseph Reynolds, Mario Castro, Carmen Molina‐París
Published Online: May 28 2019
DOI:10.1002/wsbm.1447

Abstract Full article on Wiley Online Library:   HTML | PDF
Towards multiscale modeling of the CD8+ T cell response to viral infections

Advanced Review
Subhasish Baral, Rubesh Raja, Pramita Sen, Narendra M. Dixit
Published Online: Feb 27 2019
DOI:10.1002/wsbm.1446

Abstract Full article on Wiley Online Library:   HTML | PDF
Recent advancement of light‐based single‐molecule approaches for studying biomolecules

Focus Article
Kyu Young Han, Ryan M. Gelfand, Youngbin Lim, Chenyi Zhang, Benjamin Croop
Published Online: Feb 06 2019
DOI:10.1002/wsbm.1445

Abstract Full article on Wiley Online Library:   HTML | PDF
Models of polymer physics for the architecture of the cell nucleus

Focus Article
Andrea Esposito, Carlo Annunziatella, Simona Bianco, Andrea M. Chiariello, Luca Fiorillo, Mario Nicodemi
Published Online: Dec 19 2018
DOI:10.1002/wsbm.1444

Abstract Full article on Wiley Online Library:   HTML | PDF
Integrating molecular networks with genetic variant interpretation for precision medicine

Overview
Hannah Carter, Kivilcim Ozturk, Emidio Capriotti
Published Online: Dec 12 2018
DOI:10.1002/wsbm.1443

Abstract Full article on Wiley Online Library:   HTML | PDF
Computational methods for analyzing and modeling genome structure and organization

Focus Article
Dejun Lin, Giancarlo Bonora, Galip Gürkan Yardımcı, William S. Noble
Published Online: Jul 18 2018
DOI:10.1002/wsbm.1435

Abstract Full article on Wiley Online Library:   HTML | PDF
Computational anatomy and diffeomorphometry: A dynamical systems model of neuroanatomy in the soft condensed matter continuum

Advanced Review
Laurent Younes, Daniel J. Tward, Sylvain Arguillère, Michael I. Miller
Published Online: Jun 04 2018
DOI:10.1002/wsbm.1425

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems approaches to optimizing deep brain stimulation therapies in Parkinson’s disease

Overview
Sabato Santaniello, John T. Gale, Sridevi V. Sarma
Published Online: Mar 20 2018
DOI:10.1002/wsbm.1421

Abstract Full article on Wiley Online Library:   HTML | PDF
Multiscale systems biology of trauma‐induced coagulopathy

Focus Article
Scott L. Diamond, Talid Sinno, Carrie Sims, Evan Tsiklidis
Published Online: Feb 27 2018
DOI:10.1002/wsbm.1418

Abstract Full article on Wiley Online Library:   HTML | PDF
Surveying the landscape of optogenetic methods for detection of protein–protein interactions

Advanced Review
Matthew D. Wiens, Robert E. Campbell
Published Online: Jan 15 2018
DOI:10.1002/wsbm.1415

Abstract Full article on Wiley Online Library:   HTML | PDF
Genome‐scale metabolic models applied to human health and disease

Advanced Review
Daniel J Cook, Jens Nielsen
Published Online: Jun 23 2017
DOI:10.1002/wsbm.1393

Abstract Full article on Wiley Online Library:   HTML | PDF
Image‐based computational fluid dynamics in the lung: virtual reality or new clinical practice?

Advanced Review
Haribalan Kumar, Jan De Backer, Kelly S. Burrowes
Published Online: Jun 13 2017
DOI:10.1002/wsbm.1392

Abstract Full article on Wiley Online Library:   HTML | PDF
The best models of metabolism

Advanced Review
Eberhard O. Voit
Published Online: May 19 2017
DOI:10.1002/wsbm.1391

Abstract Full article on Wiley Online Library:   HTML | PDF
Biomechanics of the human uterus

Focus Article
Kristin M. Myers, David Elad
Published Online: May 12 2017
DOI:10.1002/wsbm.1388

Abstract Full article on Wiley Online Library:   HTML | PDF
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