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WIREs Syst Biol Med
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Analytical and Computational Methods

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Systems biology approaches for identifying adverse drug reactions and elucidating their underlying biological mechanisms

Advanced Review
Mary Regina Boland, Alexandra Jacunski, Tal Lorberbaum, Joseph D. Romano, Robert Moskovitch, Nicholas P. Tatonetti
Published Online: Nov 12 2015
DOI:10.1002/wsbm.1323

Abstract Full article on Wiley Online Library:   HTML | PDF
The virtual intestine: in silico modeling of small intestinal electrophysiology and motility and the applications

Advanced Review
Peng Du, Niranchan Paskaranandavadivel, Timothy R. Angeli, Leo K. Cheng, Gregory O'Grady
Published Online: Nov 12 2015
DOI:10.1002/wsbm.1324

Abstract Full article on Wiley Online Library:   HTML | PDF
In search for symmetries in the metabolism of cancer

Advanced Review
Francesco Gatto, Jens Nielsen
Published Online: Nov 05 2015
DOI:10.1002/wsbm.1321

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology and mechanics of growth

Advanced Review
Mona Eskandari, Ellen Kuhl
Published Online: Sep 09 2015
DOI:10.1002/wsbm.1312

Abstract Full article on Wiley Online Library:   HTML | PDF
Integrative biomarker discovery in neurodegenerative diseases

Overview
André V. Carreiro, Alexandre Mendonça, Mamede de Carvalho, Sara C. Madeira
Published Online: Jul 02 2015
DOI:10.1002/wsbm.1310

Abstract Full article on Wiley Online Library:   HTML | PDF
Measurement and modeling of coronary blood flow

Overview
Matthew D. Sinclair, Jack Lee, Andrew N. Cookson, Simone Rivolo, Eoin R. Hyde, Nicolas P. Smith
Published Online: Jun 30 2015
DOI:10.1002/wsbm.1309

Abstract Full article on Wiley Online Library:   HTML | PDF
Metabolic network modeling of microbial communities

Advanced Review
Matthew B. Biggs, Gregory L. Medlock, Glynis L. Kolling, Jason A. Papin
Published Online: Jun 24 2015
DOI:10.1002/wsbm.1308

Abstract Full article on Wiley Online Library:   HTML | PDF
Implementation of integral feedback control in biological systems

Advanced Review
Pramod R. Somvanshi, Anilkumar K. Patel, Sharad Bhartiya, K. V. Venkatesh
Published Online: Jun 02 2015
DOI:10.1002/wsbm.1307

Abstract Full article on Wiley Online Library:   HTML | PDF
Genome‐wide association studies in biliary atresia

Advanced Review
Mylarappa Ningappa, Jun Min, Brandon W. Higgs, Chethan Ashokkumar, Sarangarajan Ranganathan, Rakesh Sindhi
Published Online: May 11 2015
DOI:10.1002/wsbm.1303

Abstract Full article on Wiley Online Library:   HTML | PDF
Bringing computational models of bone regeneration to the clinic

Advanced Review
Aurélie Carlier, Liesbet Geris, Johan Lammens, Hans Van Oosterwyck
Published Online: Apr 21 2015
DOI:10.1002/wsbm.1299

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems medicine: evolution of systems biology from bench to bedside

Overview
Rui‐Sheng Wang, Bradley A. Maron, Joseph Loscalzo
Published Online: Apr 17 2015
DOI:10.1002/wsbm.1297

Abstract Full article on Wiley Online Library:   HTML | PDF
Integration of systems glycobiology with bioinformatics toolboxes, glycoinformatics resources, and glycoproteomics data

Advanced Review
Gang Liu, Sriram Neelamegham
Published Online: Apr 13 2015
DOI:10.1002/wsbm.1296

Abstract Full article on Wiley Online Library:   HTML | PDF
Integrative models of vascular remodeling during tumor growth

Advanced Review
Heiko Rieger, Michael Welter
Published Online: Mar 21 2015
DOI:10.1002/wsbm.1295

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of polycystic kidney disease: a critical review

Focus Article
Luis Fernando Menezes, Gregory G. Germino
Published Online: Feb 02 2015
DOI:10.1002/wsbm.1289

Abstract Full article on Wiley Online Library:   HTML | PDF
Network representations of immune system complexity

Overview
Naeha Subramanian, Parizad Torabi‐Parizi, Rachel A. Gottschalk, Ronald N. Germain, Bhaskar Dutta
Published Online: Jan 27 2015
DOI:10.1002/wsbm.1288

Abstract Full article on Wiley Online Library:   HTML | PDF
Integrating multi‐scale knowledge on cardiac development into a computational model of ventricular trabeculation

Focus Article
Bouke A. de Boer, Jean‐François Le Garrec, Vincent M. Christoffels, Sigolène M. Meilhac, Jan M. Ruijter
Published Online: Oct 06 2014
DOI:10.1002/wsbm.1285

Abstract Full article on Wiley Online Library:   HTML | PDF
Tuneable resolution as a systems biology approach for multi‐scale, multi‐compartment computational models

Advanced Review
Denise E. Kirschner, C. Anthony Hunt, Simeone Marino, Mohammad Fallahi‐Sichani, Jennifer J. Linderman
Published Online: Aug 08 2014
DOI:10.1002/wsbm.1270

Abstract Full article on Wiley Online Library:   HTML | PDF
Large scale molecular simulations of nanotoxicity

Focus Article
Camilo A. Jimenez‐Cruz, Seung‐gu Kang, Ruhong Zhou
Published Online: Aug 08 2014
DOI:10.1002/wsbm.1271

Abstract Full article on Wiley Online Library:   HTML | PDF
Comparative epigenomics: defining and utilizing epigenomic variations across species, time‐course, and individuals

Opinion
Shu Xiao, Xiaoyi Cao, Sheng Zhong
Published Online: Jul 15 2014
DOI:10.1002/wsbm.1274

Abstract Full article on Wiley Online Library:   HTML | PDF
Boolean modeling: a logic‐based dynamic approach for understanding signaling and regulatory networks and for making useful predictions

Overview
Réka Albert, Juilee Thakar
Published Online: Jul 15 2014
DOI:10.1002/wsbm.1273

Abstract Full article on Wiley Online Library:   HTML | PDF
Personalizing oncology treatments by predicting drug efficacy, side‐effects, and improved therapy: mathematics, statistics, and their integration

Advanced Review
Zvia Agur, Moran Elishmereni, Yuri Kheifetz
Published Online: Mar 06 2014
DOI:10.1002/wsbm.1263

Abstract Full article on Wiley Online Library:   HTML | PDF
Recent advances in computational methodology for simulation of mechanical circulatory assist devices

Advanced Review
Marek Behr, Christopher C. Long, Yuri Bazilevs, Alison L. Marsden
Published Online: Jan 21 2014
DOI:10.1002/wsbm.1260

Abstract Full article on Wiley Online Library:   HTML | PDF
Using systems biology approaches to understand cardiac inflammation and extracellular matrix remodeling in the setting of myocardial infarction

Advanced Review
Omid Ghasemi, Yonggang Ma, Merry L. Lindsey, Yu‐Fang Jin
Published Online: Nov 08 2013
DOI:10.1002/wsbm.1248

Abstract Full article on Wiley Online Library:   HTML | PDF
miRNA regulation in the context of functional protein networks: principles and applications

Focus Article
Mohammed Alshalalfa
Published Online: Nov 08 2013
DOI:10.1002/wsbm.1251

Abstract Full article on Wiley Online Library:   HTML | PDF
Rule‐based modeling: a computational approach for studying biomolecular site dynamics in cell signaling systems

Overview
Lily A. Chylek, Leonard A. Harris, Chang‐Shung Tung, James R. Faeder, Carlos F. Lopez, William S. Hlavacek
Published Online: Sep 30 2013
DOI:10.1002/wsbm.1245

Abstract Full article on Wiley Online Library:   HTML | PDF
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