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Regulatory Biology

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Lights up on organelles: Optogenetic tools to control subcellular structure and organization

Advanced Review
Therese C. Kichuk, César Carrasco‐López, José L. Avalos
Published Online: Jul 26 2020
DOI:10.1002/wsbm.1500

Abstract Full article on Wiley Online Library:   HTML | PDF
Liver gene regulatory networks: Contributing factors to nonalcoholic fatty liver disease

Advanced Review
Inês Cebola
Published Online: Feb 04 2020
DOI:10.1002/wsbm.1480

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of robustness and homeostatic mechanisms

Overview
H. Frederik Nijhout, Janet A. Best, Michael C. Reed
Published Online: Oct 29 2018
DOI:10.1002/wsbm.1440

Abstract Full article on Wiley Online Library:   HTML | PDF
The mechanistic basis for chromatin regulation by pioneer transcription factors

Advanced Review
Makiko Iwafuchi‐Doi
Published Online: Jun 27 2018
DOI:10.1002/wsbm.1427

Abstract Full article on Wiley Online Library:   HTML | PDF
Diversification of transcription factor–DNA interactions and the evolution of gene regulatory networks

Advanced Review
Julia M. Rogers, Martha L. Bulyk
Published Online: Apr 25 2018
DOI:10.1002/wsbm.1423

Abstract Full article on Wiley Online Library:   HTML | PDF
Multiscale systems biology of trauma‐induced coagulopathy

Focus Article
Evan Tsiklidis, Carrie Sims, Talid Sinno, Scott L. Diamond
Published Online: Feb 27 2018
DOI:10.1002/wsbm.1418

Abstract Full article on Wiley Online Library:   HTML | PDF
Genome organization during the cell cycle: unity in division

Focus Article
Rosela Golloshi, Jacob T. Sanders, Rachel Patton McCord
Published Online: May 16 2017
DOI:10.1002/wsbm.1389

Abstract Full article on Wiley Online Library:   HTML | PDF
Regulatory elements in molecular networks

Advanced Review
Ashley S. Doane, Olivier Elemento
Published Online: Jan 17 2017
DOI:10.1002/wsbm.1374

Abstract Full article on Wiley Online Library:   HTML | PDF
Cancer and inflammation

Overview
Lance L. Munn
Published Online: Dec 12 2016
DOI:10.1002/wsbm.1370

Abstract Full article on Wiley Online Library:   HTML | PDF
Omics‐based approaches to understand mechanosensitive endothelial biology and atherosclerosis

Advanced Review
Rachel D. Simmons, Sandeep Kumar, Salim Raid Thabet, Sanjoli Sur, Hanjoong Jo
Published Online: Jun 24 2016
DOI:10.1002/wsbm.1344

Abstract Full article on Wiley Online Library:   HTML | PDF
The reverse control of irreversible biological processes

Opinion
Kwang‐Hyun Cho, Jae Il Joo, Dongkwan Shin, Dongsan Kim, Sang‐Min Park
Published Online: Jun 21 2016
DOI:10.1002/wsbm.1346

Abstract Full article on Wiley Online Library:   HTML | PDF
Adaptive resistance to antibiotics in bacteria: a systems biology perspective

Advanced Review
Santiago Sandoval‐Motta, Maximino Aldana
Published Online: Apr 21 2016
DOI:10.1002/wsbm.1335

Abstract Full article on Wiley Online Library:   HTML | PDF
Dynamics of the mammalian cell cycle in physiological and pathological conditions

Focus Article
Claude Gérard, Albert Goldbeter
Published Online: Nov 27 2015
DOI:10.1002/wsbm.1325

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems analysis of host–parasite interactions

Advanced Review
Justine Swann, Neema Jamshidi, Nathan E. Lewis, Elizabeth A. Winzeler
Published Online: Aug 26 2015
DOI:10.1002/wsbm.1311

Abstract Full article on Wiley Online Library:   HTML | PDF
Topology, dynamics, and heterogeneity in immune signaling

Advanced Review
J. Taylor Webb, Marcelo Behar
Published Online: May 27 2015
DOI:10.1002/wsbm.1306

Abstract Full article on Wiley Online Library:   HTML | PDF
Experience‐sensitive epigenetic mechanisms, developmental plasticity, and the biological embedding of chronic disease risk

Overview
Vincent T. Cunliffe
Published Online: Feb 20 2015
DOI:10.1002/wsbm.1291

Abstract Full article on Wiley Online Library:   HTML | PDF
Genome network medicine: innovation to overcome huge challenges in cancer therapy

Focus Article
Dimitrios H. Roukos
Published Online: Dec 06 2013
DOI:10.1002/wsbm.1254

Abstract Full article on Wiley Online Library:   HTML | PDF
Regulatory variation: an emerging vantage point for cancer biology

Overview
Luolan Li, Alireza Lorzadeh, Martin Hirst
Published Online: Nov 19 2013
DOI:10.1002/wsbm.1250

Abstract Full article on Wiley Online Library:   HTML | PDF
miRNA regulation in the context of functional protein networks: principles and applications

Focus Article
Mohammed Alshalalfa
Published Online: Nov 08 2013
DOI:10.1002/wsbm.1251

Abstract Full article on Wiley Online Library:   HTML | PDF
Neural stem and progenitor cells in health and disease

Advanced Review
Ian Ladran, Ngoc Tran, Aaron Topol, Kristen J. Brennand
Published Online: Sep 20 2013
DOI:10.1002/wsbm.1239

Abstract Full article on Wiley Online Library:   HTML | PDF
Cell‐specific integration of nuclear receptor function at the genome

Focus Article
Logan J. Everett, Mitchell A. Lazar
Published Online: Jun 11 2013
DOI:10.1002/wsbm.1231

Abstract Full article on Wiley Online Library:   HTML | PDF
Hierarchical approaches for systems modeling in cardiac development

Overview
Russell A. Gould, Lina M. Aboulmouna, Jeffrey D. Varner, Jonathan T. Butcher
Published Online: Mar 05 2013
DOI:10.1002/wsbm.1217

Abstract Full article on Wiley Online Library:   HTML | PDF
Engineered genetic information processing circuits

Overview
Hao Qi, Andrew Blanchard, Ting Lu
Published Online: Feb 26 2013
DOI:10.1002/wsbm.1216

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of adipose tissue metabolism: regulation of growth, signaling and inflammation

Advanced Review
Sara Manteiga, Kyungoh Choi, Arul Jayaraman, Kyongbum Lee
Published Online: Feb 13 2013
DOI:10.1002/wsbm.1213

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of lung development and regeneration: current knowledge and recommendations for future research

Opinion
James S. Hagood, Namasivayam Ambalavanan
Published Online: Jan 04 2013
DOI:10.1002/wsbm.1205

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology approaches to finding novel pain mediators

Advanced Review
Ana Antunes‐Martins, James R. Perkins, Jonathan Lees, Tobias Hildebrandt, Christine Orengo, David L.H. Bennett
Published Online: Oct 11 2012
DOI:10.1002/wsbm.1192

Abstract Full article on Wiley Online Library:   HTML | PDF
Role of fibroblast growth factor signaling in vascular formation and maintenance: orchestrating signaling networks as an integrated system

Focus Article
Masahiro Murakami, Takashi Sakurai
Published Online: Aug 28 2012
DOI:10.1002/wsbm.1190

Abstract Full article on Wiley Online Library:   HTML | PDF
Post‐translational modification: nature's escape from genetic imprisonment and the basis for dynamic information encoding

Advanced Review
Guy Lippens, Hanno Steen, Jeremy Gunawardena, Sudhakaran Prabakaran
Published Online: Aug 15 2012
DOI:10.1002/wsbm.1185

Abstract Full article on Wiley Online Library:   HTML | PDF
The role of regulatory T cells in neurodegenerative diseases

Advanced Review
Feng He, Rudi Balling
Published Online: Aug 15 2012
DOI:10.1002/wsbm.1187

Abstract Full article on Wiley Online Library:   HTML | PDF
Decoding the functions of post‐transcriptional regulators in the determination of inflammatory states: focus on macrophage activation

Focus Article
Panagiota Kafasla, Ioannis Karakasiliotis, Dimitris L. Kontoyiannis
Published Online: Jul 03 2012
DOI:10.1002/wsbm.1179

Abstract Full article on Wiley Online Library:   HTML | PDF
Linking genome to epigenome

Focus Article
Guo‐Cheng Yuan
Published Online: Feb 17 2012
DOI:10.1002/wsbm.1165

Abstract Full article on Wiley Online Library:   HTML | PDF
Reverse‐engineering human regulatory networks

Advanced Review
Celine Lefebvre, Gabrielle Rieckhof, Andrea Califano
Published Online: Jan 13 2012
DOI:10.1002/wsbm.1159

Abstract Full article on Wiley Online Library:   HTML | PDF
Multiscale models of thrombogenesis

Advanced Review
Zhiliang Xu, Oleg Kim, Malgorzata Kamocka, Elliot D. Rosen, Mark Alber
Published Online: Jan 13 2012
DOI:10.1002/wsbm.1160

Abstract Full article on Wiley Online Library:   HTML | PDF
Noncoding RNAs in gene regulation

Focus Article
Maxime Wery, Marta Kwapisz, Antonin Morillon
Published Online: Mar 04 2011
DOI:10.1002/wsbm.148

Abstract Full article on Wiley Online Library:   HTML | PDF
Role of the nuclear envelope in genome organization and gene expression

Advanced Review
David W. Van de Vosse, Yakun Wan, Richard W. Wozniak, John D. Aitchison
Published Online: Feb 08 2011
DOI:10.1002/wsbm.101

Abstract Full article on Wiley Online Library:   HTML | PDF
Adaptation of cells to new environments

Advanced Review
Aaron N. Brooks, Serdar Turkarslan, Karlyn D. Beer, Fang Yin Lo, Nitin S. Baliga
Published Online: Dec 31 2010
DOI:10.1002/wsbm.136

Abstract Full article on Wiley Online Library:   HTML | PDF
Network biology: a direct approach to study biological function

Overview
Frank Emmert‐Streib, Galina V. Glazko
Published Online: Dec 31 2010
DOI:10.1002/wsbm.134

Abstract Full article on Wiley Online Library:   HTML | PDF
Advances in analysis of transcriptional regulatory networks

Advanced Review
Tae‐Min Kim, Peter J. Park
Published Online: Dec 16 2010
DOI:10.1002/wsbm.105

Abstract Full article on Wiley Online Library:   HTML | PDF
Mediators and dynamics of DNA methylation

Advanced Review
Robert Shoemaker, Wei Wang, Kun Zhang
Published Online: Sep 28 2010
DOI:10.1002/wsbm.124

Abstract Full article on Wiley Online Library:   HTML | PDF
Protein–protein interaction networks and subnetworks in the biology of disease

Focus Article
Rod K. Nibbe, Salim A. Chowdhury, Mehmet Koyutürk, Rob Ewing, Mark R. Chance
Published Online: Sep 23 2010
DOI:10.1002/wsbm.121

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems analysis of alternative splicing and its regulation

Advanced Review
Xinshu Xiao, Jae‐Hyung Lee
Published Online: Aug 04 2010
DOI:10.1002/wsbm.84

Abstract Full article on Wiley Online Library:   HTML | PDF
APOBEC‐1‐mediated RNA editing

Focus Article
Valerie Blanc, Nicholas O. Davidson
Published Online: Aug 04 2010
DOI:10.1002/wsbm.82

Abstract Full article on Wiley Online Library:   HTML | PDF
DNA methylation and gene expression

Focus Article
Zahava Siegfried, Itamar Simon
Published Online: Apr 09 2010
DOI:10.1002/wsbm.64

Abstract Full article on Wiley Online Library:   HTML | PDF
MicroRNA targeting in mammalian genomes: genes and mechanisms

Advanced Review
S. A. Muljo, C. Kanellopoulou, L. Aravind
Published Online: Mar 26 2010
DOI:10.1002/wsbm.53

Abstract Full article on Wiley Online Library:   HTML | PDF
Systematic analysis of posttranscriptional gene expression

Advanced Review
Adam R. Morris, Neelanjan Mukherjee, Jack D. Keene
Published Online: Mar 26 2010
DOI:10.1002/wsbm.54

Abstract Full article on Wiley Online Library:   HTML | PDF
Circuitry of mRNA regulation

Focus Article
Alexander Kanitz, André P. Gerber
Published Online: Mar 26 2010
DOI:10.1002/wsbm.55

Abstract Full article on Wiley Online Library:   HTML | PDF
DNA methylation alterations in multiple myeloma as a model for epigenetic changes in cancer

Advanced Review
Amy Sharma, Christoph J. Heuck, Melissa J. Fazzari, Jayesh Mehta, Seema Singhal, John M. Greally, Amit Verma
Published Online: Mar 24 2010
DOI:10.1002/wsbm.89

Abstract Full article on Wiley Online Library:   HTML | PDF
Adenosine‐to‐inosine RNA editing

Focus Article
Boris Zinshteyn, Kazuko Nishikura
Published Online: Sep 22 2009
DOI:10.1002/wsbm.10

Abstract Full article on Wiley Online Library:   HTML | PDF
Regulation of endothelial cell functions by basement membrane‐ and arachidonic acid‐derived products

Focus Article
Ambra Pozzi, Roy Zent
Published Online: Sep 22 2009
DOI:10.1002/wsbm.7

Abstract Full article on Wiley Online Library:   HTML | PDF
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