Understanding the mTOR signaling pathway via mathematical modeling
Advanced Review
Nurgazy Sulaimanov, Martin Klose, Hauke Busch, Melanie Boerries
Published Online: Feb 10 2017
DOI:10.1002/wsbm.1379
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Mechanistic Models
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Mechanistic Models
Regulating cellular cyclic adenosine monophosphate: “Sources,” “sinks,” and now, “tunable valves”
Focus Article
Pradipta Ghosh, Padmini Rangamani, Michael Getz
Published Online: Apr 23 2020
DOI:10.1002/wsbm.1490
Molecular networks in Network Medicine: Development and applications
Advanced Review
Edwin K. Silverman, Harald H. H. W. Schmidt, Eleni Anastasiadou, Lucia Altucci, Marco Angelini, Lina Badimon, Jean‐Luc Balligand, Giuditta Benincasa, Giovambattista Capasso, Federica Conte, Antonella Di Costanzo, Lorenzo Farina, Giulia Fiscon, Laurent Gatto, Michele Gentili, Joseph Loscalzo, Cinzia Marchese, Claudio Napoli, Paola Paci, Manuela Petti, John Quackenbush, Paolo Tieri, Davide Viggiano, Gemma Vilahur, Kimberly Glass, Jan Baumbach
Published Online: Apr 20 2020
DOI:10.1002/wsbm.1489
Multiscale modeling of vertebrate limb development
Advanced Review
Tilmann Glimm, Ramray Bhat, Stuart A. Newman
Published Online: Mar 25 2020
DOI:10.1002/wsbm.1485
Aspirin and the chemoprevention of cancers: A mathematical and evolutionary dynamics perspective
Advanced Review
Natalia L. Komarova, C. Richard Boland, Ajay Goel, Dominik Wodarz
Published Online: Mar 12 2020
DOI:10.1002/wsbm.1487
Modeling immune cell behavior across scales in cancer
Advanced Review
Stacey D. Finley, Colin G. Cess, Sahak Z. Makaryan
Published Online: Mar 04 2020
DOI:10.1002/wsbm.1484
Cholesterol interaction motifs in G protein‐coupled receptors: Slippery hot spots?
Advanced Review
Parijat Sarkar, Amitabha Chattopadhyay
Published Online: Feb 07 2020
DOI:10.1002/wsbm.1481
Theory of cell fate
Primer
Michael J. Casey, Patrick S. Stumpf, Ben D. MacArthur
Published Online: Dec 12 2019
DOI:10.1002/wsbm.1471
Exploring cardiac form and function: A length‐scale computational biology approach
Advanced Review
William F. Sherman, Anna Grosberg
Published Online: Dec 02 2019
DOI:10.1002/wsbm.1470
Stochastic simulation algorithms for computational systems biology: Exact, approximate, and hybrid methods
Advanced Review
Luca Marchetti, Corrado Priami, Federico Reali, Giulia Simoni
Published Online: Jul 01 2019
DOI:10.1002/wsbm.1459
Agent‐based models of inflammation in translational systems biology: A decade later
UPDATE
Gary An, Yoram Vodovotz
Published Online: Jul 01 2019
DOI:10.1002/wsbm.1460
IL7 receptor signaling in T cells: A mathematical modeling perspective
Overview
Jung‐Hyun Park, Adam T. Waickman, Joseph Reynolds, Mario Castro, Carmen Molina‐París
Published Online: May 28 2019
DOI:10.1002/wsbm.1447
Essential contributions of enhancer genomic regulatory elements to microglial cell identity and functions
Focus Article
André Machado Xavier, Sarah Belhocine, David Gosselin
Published Online: Apr 23 2019
DOI:10.1002/wsbm.1449
Calcium signals that determine vascular resistance
Focus Article
Matteo Ottolini, Kwangseok Hong, Swapnil K. Sonkusare
Published Online: Mar 18 2019
DOI:10.1002/wsbm.1448
Towards multiscale modeling of the CD8+ T cell response to viral infections
Advanced Review
Subhasish Baral, Rubesh Raja, Pramita Sen, Narendra M. Dixit
Published Online: Feb 27 2019
DOI:10.1002/wsbm.1446
Integrating molecular networks with genetic variant interpretation for precision medicine
Overview
Hannah Carter, Kivilcim Ozturk, Emidio Capriotti
Published Online: Dec 12 2018
DOI:10.1002/wsbm.1443
Systems biology of robustness and homeostatic mechanisms
Overview
Michael C. Reed, Janet A. Best, H. Frederik Nijhout
Published Online: Oct 29 2018
DOI:10.1002/wsbm.1440
Context‐dependent regulation of receptor tyrosine kinases: Insights from systems biology approaches
Focus Article
Inez Lam, Christina M. Pickering, Feilim Mac Gabhann
Published Online: Sep 26 2018
DOI:10.1002/wsbm.1437
Computational methods for analyzing and modeling genome structure and organization
Focus Article
Dejun Lin, Giancarlo Bonora, Galip Gürkan Yardımcı, William S. Noble
Published Online: Jul 18 2018
DOI:10.1002/wsbm.1435
Quantitative systems models illuminate arrhythmia mechanisms in heart failure: Role of the Na+‐Ca2+‐Ca2+/calmodulin‐dependent protein kinase II‐reactive oxygen species feedback
Focus Article
Stefano Morotti, Eleonora Grandi
Published Online: Jul 17 2018
DOI:10.1002/wsbm.1434
Kinetic models of hematopoietic differentiation
Advanced Review
Victor Olariu, Carsten Peterson
Published Online: Apr 16 2018
DOI:10.1002/wsbm.1424
Multiscale systems biology of trauma‐induced coagulopathy
Focus Article
Evan Tsiklidis, Carrie Sims, Talid Sinno, Scott L. Diamond
Published Online: Feb 27 2018
DOI:10.1002/wsbm.1418
Image‐based computational fluid dynamics in the lung: virtual reality or new clinical practice?
Advanced Review
Kelly S. Burrowes, Jan De Backer, Haribalan Kumar
Published Online: Jun 13 2017
DOI:10.1002/wsbm.1392
The best models of metabolism
Advanced Review
Eberhard O. Voit
Published Online: May 19 2017
DOI:10.1002/wsbm.1391
Systems biology of cellular membranes: a convergence with biophysics
Advanced Review
Morgan Chabanon, Jeanne C. Stachowiak, Padmini Rangamani
Published Online: May 05 2017
DOI:10.1002/wsbm.1386