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WIREs Syst Biol Med
Impact Factor: 4.192

Computational Methods

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Integrative models of vascular remodeling during tumor growth

Advanced Review
Heiko Rieger, Michael Welter
Published Online: Mar 21 2015
DOI:10.1002/wsbm.1295

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology of polycystic kidney disease: a critical review

Focus Article
Luis Fernando Menezes, Gregory G. Germino
Published Online: Feb 02 2015
DOI:10.1002/wsbm.1289

Abstract Full article on Wiley Online Library:   HTML | PDF
Network representations of immune system complexity

Overview
Naeha Subramanian, Parizad Torabi‐Parizi, Rachel A. Gottschalk, Ronald N. Germain, Bhaskar Dutta
Published Online: Jan 27 2015
DOI:10.1002/wsbm.1288

Abstract Full article on Wiley Online Library:   HTML | PDF
Integrating multi‐scale knowledge on cardiac development into a computational model of ventricular trabeculation

Focus Article
Bouke A. de Boer, Jean‐François Le Garrec, Vincent M. Christoffels, Sigolène M. Meilhac, Jan M. Ruijter
Published Online: Oct 06 2014
DOI:10.1002/wsbm.1285

Abstract Full article on Wiley Online Library:   HTML | PDF
Tuneable resolution as a systems biology approach for multi‐scale, multi‐compartment computational models

Advanced Review
Denise E. Kirschner, C. Anthony Hunt, Simeone Marino, Mohammad Fallahi‐Sichani, Jennifer J. Linderman
Published Online: Aug 08 2014
DOI:10.1002/wsbm.1270

Abstract Full article on Wiley Online Library:   HTML | PDF
Large scale molecular simulations of nanotoxicity

Focus Article
Camilo A. Jimenez‐Cruz, Seung‐gu Kang, Ruhong Zhou
Published Online: Aug 08 2014
DOI:10.1002/wsbm.1271

Abstract Full article on Wiley Online Library:   HTML | PDF
Personalizing oncology treatments by predicting drug efficacy, side‐effects, and improved therapy: mathematics, statistics, and their integration

Advanced Review
Zvia Agur, Moran Elishmereni, Yuri Kheifetz
Published Online: Mar 06 2014
DOI:10.1002/wsbm.1263

Abstract Full article on Wiley Online Library:   HTML | PDF
Recent advances in computational methodology for simulation of mechanical circulatory assist devices

Advanced Review
Alison L. Marsden, Yuri Bazilevs, Christopher C. Long, Marek Behr
Published Online: Jan 21 2014
DOI:10.1002/wsbm.1260

Abstract Full article on Wiley Online Library:   HTML | PDF
Using systems biology approaches to understand cardiac inflammation and extracellular matrix remodeling in the setting of myocardial infarction

Advanced Review
Omid Ghasemi, Yonggang Ma, Merry L. Lindsey, Yu‐Fang Jin
Published Online: Nov 08 2013
DOI:10.1002/wsbm.1248

Abstract Full article on Wiley Online Library:   HTML | PDF
miRNA regulation in the context of functional protein networks: principles and applications

Focus Article
Mohammed Alshalalfa
Published Online: Nov 08 2013
DOI:10.1002/wsbm.1251

Abstract Full article on Wiley Online Library:   HTML | PDF
Rule‐based modeling: a computational approach for studying biomolecular site dynamics in cell signaling systems

Overview
Lily A. Chylek, Leonard A. Harris, Chang‐Shung Tung, James R. Faeder, Carlos F. Lopez, William S. Hlavacek
Published Online: Sep 30 2013
DOI:10.1002/wsbm.1245

Abstract Full article on Wiley Online Library:   HTML | PDF
Computational approaches for understanding energy metabolism

Focus Article
Alexander A. Shestov, Brandon Barker, Zhenglong Gu, Jason W. Locasale
Published Online: Jul 29 2013
DOI:10.1002/wsbm.1238

Abstract Full article on Wiley Online Library:   HTML | PDF
Mathematical modeling of kidney transport

Advanced Review
Anita T. Layton
Published Online: Jul 12 2013
DOI:10.1002/wsbm.1232

Abstract Full article on Wiley Online Library:   HTML | PDF
Multiscale image‐based modeling and simulation of gas flow and particle transport in the human lungs

Focus Article
Ching‐Long Lin, Merryn H. Tawhai, Eric A. Hoffman
Published Online: Jul 10 2013
DOI:10.1002/wsbm.1234

Abstract Full article on Wiley Online Library:   HTML | PDF
Engineered genetic information processing circuits

Overview
Hao Qi, Andrew Blanchard, Ting Lu
Published Online: Feb 26 2013
DOI:10.1002/wsbm.1216

Abstract Full article on Wiley Online Library:   HTML | PDF
Bioimage informatics for understanding spatiotemporal dynamics of cellular processes

Advanced Review
Ge Yang
Published Online: Feb 13 2013
DOI:10.1002/wsbm.1214

Abstract Full article on Wiley Online Library:   HTML | PDF
Model‐based design of experiments for cellular processes

Advanced Review
Ankush Chakrabarty, Gregery T. Buzzard, Ann E. Rundell
Published Online: Jan 04 2013
DOI:10.1002/wsbm.1204

Abstract Full article on Wiley Online Library:   HTML | PDF
Accelerating cancer systems biology research through Semantic Web technology

Overview
Zhihui Wang, Jonathan Sagotsky, Thomas Taylor, Patrick Shironoshita, Thomas S. Deisboeck
Published Online: Nov 27 2012
DOI:10.1002/wsbm.1200

Abstract Full article on Wiley Online Library:   HTML | PDF
From base pair to bedside: molecular simulation and the translation of genomics to personalized medicine

Advanced Review
David W. Wright, Shunzhou Wan, Nour Shublaq, Stefan J. Zasada, Peter V. Coveney
Published Online: Aug 15 2012
DOI:10.1002/wsbm.1186

Abstract Full article on Wiley Online Library:   HTML | PDF
Systems biology approaches to toll‐like receptor signaling

Focus Article
Alexis Vandenbon, Shunsuke Teraguchi, Shizuo Akira, Kiyoshi Takeda, Daron M. Standley
Published Online: Jun 19 2012
DOI:10.1002/wsbm.1178

Abstract Full article on Wiley Online Library:   HTML | PDF
Recent approaches to the prioritization of candidate disease genes

Advanced Review
Nadezhda T. Doncheva, Tim Kacprowski, Mario Albrecht
Published Online: Jun 11 2012
DOI:10.1002/wsbm.1177

Abstract Full article on Wiley Online Library:   HTML | PDF
Linking genome to epigenome

Focus Article
Guo‐Cheng Yuan
Published Online: Feb 17 2012
DOI:10.1002/wsbm.1165

Abstract Full article on Wiley Online Library:   HTML | PDF
Mass spectrometry‐based proteomics: qualitative identification to activity‐based protein profiling

Advanced Review
Job D. Cardoza, Jignesh R. Parikh, Scott B. Ficarro, Jarrod A. Marto
Published Online: Jan 09 2012
DOI:10.1002/wsbm.166

Abstract Full article on Wiley Online Library:   HTML | PDF
Virtual Cell: computational tools for modeling in cell biology

Advanced Review
Diana C. Resasco, Fei Gao, Frank Morgan, Igor L. Novak, James C. Schaff, Boris M. Slepchenko
Published Online: Dec 02 2011
DOI:10.1002/wsbm.165

Abstract Full article on Wiley Online Library:   HTML | PDF
Integrative physical oncology

Opinion
Haralampos Hatzikirou, Arnaud Chauviere, Amy L. Bauer, André Leier, Michael T. Lewis, Paul Macklin, Tatiana T. Marquez‐Lago, Elaine L. Bearer, Vittorio Cristini
Published Online: Aug 18 2011
DOI:10.1002/wsbm.158

Abstract Full article on Wiley Online Library:   HTML | PDF
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