Systems engineering meets quantitative systems pharmacology: from low‐level targets to engaging the host defenses
Opinion
Ioannis P. Androulakis
Published Online: Mar 16 2015
DOI:10.1002/wsbm.1294
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Translational Medicine
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Translational Medicine
Liver fibrosis: Pathophysiology and clinical implications
Advanced Review
Kristin Mekeel, Tatiana Kisseleva, Jacopo Baglieri, Jennifer Berumen
Published Online: Jul 26 2020
DOI:10.1002/wsbm.1499
Molecular networks in Network Medicine: Development and applications
Advanced Review
Edwin K. Silverman, Harald H. H. W. Schmidt, Eleni Anastasiadou, Lucia Altucci, Marco Angelini, Lina Badimon, Jean‐Luc Balligand, Giuditta Benincasa, Giovambattista Capasso, Federica Conte, Antonella Di Costanzo, Lorenzo Farina, Giulia Fiscon, Laurent Gatto, Michele Gentili, Joseph Loscalzo, Cinzia Marchese, Claudio Napoli, Paola Paci, Manuela Petti, John Quackenbush, Paolo Tieri, Davide Viggiano, Gemma Vilahur, Kimberly Glass, Jan Baumbach
Published Online: Apr 20 2020
DOI:10.1002/wsbm.1489
The immunologic Warburg effect: Evidence and therapeutic opportunities in autoimmunity
Advanced Review
Michael D. Kornberg
Published Online: Feb 27 2020
DOI:10.1002/wsbm.1486
Glucose transporter 1 in rheumatoid arthritis and autoimmunity
Advanced Review
Ekaterina Zezina, Oezen Sercan‐Alp, Matthias Herrmann, Nadine Biesemann
Published Online: Feb 21 2020
DOI:10.1002/wsbm.1483
How personalized heart modeling can help treatment of lethal arrhythmias: A focus on ventricular tachycardia ablation strategies in post‐infarction patients
Advanced Review
Natalia A. Trayanova, Ashish N. Doshi, Adityo Prakosa
Published Online: Jan 09 2020
DOI:10.1002/wsbm.1477
Structural neuroimaging of the altered brain stemming from pediatric and adolescent hearing loss—Scientific and clinical challenges
Advanced Review
J. Tilak Ratnanather
Published Online: Dec 04 2019
DOI:10.1002/wsbm.1469
Agent‐based models of inflammation in translational systems biology: A decade later
UPDATE
Gary An, Yoram Vodovotz
Published Online: Jul 01 2019
DOI:10.1002/wsbm.1460
Integrating molecular networks with genetic variant interpretation for precision medicine
Overview
Emidio Capriotti, Kivilcim Ozturk, Hannah Carter
Published Online: Dec 12 2018
DOI:10.1002/wsbm.1443
PharmGKB: A worldwide resource for pharmacogenomic information
Advanced Review
Julia M. Barbarino, Michelle Whirl‐Carrillo, Russ B. Altman, Teri E. Klein
Published Online: Feb 23 2018
DOI:10.1002/wsbm.1417
Human microbiota, blood group antigens, and disease
Advanced Review
D. Rose Ewald, Susan C.J. Sumner
Published Online: Jan 09 2018
DOI:10.1002/wsbm.1413
Biomechanics of the human uterus
Focus Article
Kristin M. Myers, David Elad
Published Online: May 12 2017
DOI:10.1002/wsbm.1388
Integrated precision medicine: the role of electronic health records in delivering personalized treatment
Focus Article
Amy Sitapati, Hyeoneui Kim, Barbara Berkovich, Rebecca Marmor, Siddharth Singh, Robert El‐Kareh, Brian Clay, Lucila Ohno‐Machado
Published Online: Feb 16 2017
DOI:10.1002/wsbm.1378
Modified mRNA as a therapeutic tool to induce cardiac regeneration in ischemic heart disease
Focus Article
Yoav Hadas, Michael G. Katz, Charles R. Bridges, Lior Zangi
Published Online: Dec 02 2016
DOI:10.1002/wsbm.1367
Computational approaches for the identification of cancer genes and pathways
Advanced Review
Christos M. Dimitrakopoulos, Niko Beerenwinkel
Published Online: Nov 11 2016
DOI:10.1002/wsbm.1364
Engineering of synthetic gene circuits for (re‐)balancing physiological processes in chronic diseases
Advanced Review
Lina Schukur, Martin Fussenegger
Published Online: Jun 24 2016
DOI:10.1002/wsbm.1345
Mathematical models of breast and ovarian cancers
Advanced Review
Dana‐Adriana Botesteanu, Stanley Lipkowitz, Jung‐Min Lee, Doron Levy
Published Online: Jun 03 2016
DOI:10.1002/wsbm.1343
Systems medicine in colorectal cancer: from a mathematical model toward a new type of clinical trial
Advanced Review
Nicoletta Castagnino, Massimo Maffei, Lorenzo Tortolina, Gabriele Zoppoli, Daniela Piras, Alessio Nencioni, Eva Moran, Alberto Ballestrero, Franco Patrone, Silvio Parodi
Published Online: May 30 2016
DOI:10.1002/wsbm.1342
In silico methods for drug repurposing and pharmacology
Overview
Rachel A. Hodos, Brian A. Kidd, Khader Shameer, Ben P. Readhead, Joel T. Dudley
Published Online: Apr 15 2016
DOI:10.1002/wsbm.1337
Systems biology approaches for identifying adverse drug reactions and elucidating their underlying biological mechanisms
Advanced Review
Mary Regina Boland, Alexandra Jacunski, Tal Lorberbaum, Joseph D. Romano, Robert Moskovitch, Nicholas P. Tatonetti
Published Online: Nov 12 2015
DOI:10.1002/wsbm.1323
Integrative biomarker discovery in neurodegenerative diseases
Overview
André V. Carreiro, Alexandre Mendonça, Mamede de Carvalho, Sara C. Madeira
Published Online: Jul 02 2015
DOI:10.1002/wsbm.1310
Genome‐wide association studies in biliary atresia
Advanced Review
Mylarappa Ningappa, Jun Min, Brandon W. Higgs, Chethan Ashokkumar, Sarangarajan Ranganathan, Rakesh Sindhi
Published Online: May 11 2015
DOI:10.1002/wsbm.1303
Parsing interindividual drug variability: an emerging role for systems pharmacology
Advanced Review
Richard M. Turner, B. Kevin Park, Munir Pirmohamed
Published Online: May 07 2015
DOI:10.1002/wsbm.1302
Network pharmacodynamic models for customized cancer therapy
Focus Article
James M. Gallo, Marc R. Birtwistle
Published Online: Apr 24 2015
DOI:10.1002/wsbm.1300
Systems medicine: evolution of systems biology from bench to bedside
Overview
Rui‐Sheng Wang, Bradley A. Maron, Joseph Loscalzo
Published Online: Apr 17 2015
DOI:10.1002/wsbm.1297