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WIREs RNA
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RNA Processing

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RNA methyltransferase METTL16: Targets and function

Advanced Review
Emily R. Satterwhite, Kyle D. Mansfield
Published Online: Jul 06 2021
DOI:10.1002/wrna.1681

Abstract Full article on Wiley Online Library:   HTML | PDF
Microexon alternative splicing of small GTPase regulators: Implication in central nervous system diseases

Advanced Review
Jee‐San Lee, Nathalie Lamarche‐Vane, Stéphane Richard
Published Online: Jun 22 2021
DOI:10.1002/wrna.1678

Abstract Full article on Wiley Online Library:   HTML | PDF
Biogenesis, characterization, and functions of mirtrons

Focus Article
Perumal Vivekanandan, Ritu Kulshreshtha, Ashish Kumar, Uzma Salim
Published Online: Jun 22 2021
DOI:10.1002/wrna.1680

Abstract Full article on Wiley Online Library:   HTML | PDF
Interplay within tumor microenvironment orchestrates neoplastic RNA metabolism and transcriptome diversity

Advanced Review
Sanjeev Shukla, Srinivas Abhishek Mutnuru, Shruti Ganesh Dhamdhere, Subhashis Natua
Published Online: Jun 10 2021
DOI:10.1002/wrna.1676

Abstract Full article on Wiley Online Library:   HTML | PDF
The role of RNA editing enzyme ADAR1 in human disease

Advanced Review
Kazuko Nishikura, Moeko Minakuchi, Yusuke Shiromoto, Brian Song
Published Online: Jun 09 2021
DOI:10.1002/wrna.1665

Abstract Full article on Wiley Online Library:   HTML | PDF
Division of labor in epitranscriptomics: What have we learnt from the structures of eukaryotic and viral multimeric RNA methyltransferases?

Advanced Review
Marc Graille
Published Online: May 27 2021
DOI:10.1002/wrna.1673

Abstract Full article on Wiley Online Library:   HTML | PDF
Evolutionary driving forces of A‐to‐I editing in metazoans

Advanced Review
Jian Lu, Xiaolu Tang, Yuange Duan
Published Online: May 17 2021
DOI:10.1002/wrna.1666

Abstract Full article on Wiley Online Library:   HTML | PDF
Detecting the epitranscriptome

Advanced Review
Anwesha Sarkar, William Gasperi, Ulrike Begley, Steven Nevins, Sabrina M. Huber, Peter C. Dedon, Thomas J. Begley
Published Online: May 14 2021
DOI:10.1002/wrna.1663

Abstract Full article on Wiley Online Library:   HTML | PDF
Unannotated splicing regulatory elements in deep intron space

Advanced Review
John G. Conboy
Published Online: Apr 22 2021
DOI:10.1002/wrna.1656

Abstract Full article on Wiley Online Library:   HTML | PDF
On the function and relevance of alternative 3′‐UTRs in gene expression regulation

Advanced Review
Alexandra Moreira, Isabel Pereira‐Castro
Published Online: Apr 12 2021
DOI:10.1002/wrna.1653

Abstract Full article on Wiley Online Library:   HTML | PDF
Therapeutic promise of engineered nonsense suppressor tRNAs

Overview
John D. Lueck, Christina S. Heil, Joseph J. Porter
Published Online: Feb 10 2021
DOI:10.1002/wrna.1641

Abstract Full article on Wiley Online Library:   HTML | PDF
Splicing alterations in healthy aging and disease

Advanced Review
Olga Anczuków, Brittany Lynn Angarola
Published Online: Feb 09 2021
DOI:10.1002/wrna.1643

Abstract Full article on Wiley Online Library:   HTML | PDF
Dynamic transcriptomic m5C and its regulatory role in RNA processing

Advanced Review
Wen‐Lan Yang, Yong‐Liang Zhao, Yun‐Gui Yang, Yu‐Sheng Chen
Published Online: Jan 13 2021
DOI:10.1002/wrna.1639

Abstract Full article on Wiley Online Library:   HTML | PDF
Artificial miRNAs as therapeutic tools: Challenges and opportunities

Advanced Review
Marta Olejniczak, Marianna Pewinska, Anna Kotowska‐Zimmer
Published Online: Jan 01 2021
DOI:10.1002/wrna.1640

Abstract Full article on Wiley Online Library:   HTML | PDF
Mitochondrial RNA quality control in trypanosomes

Advanced Review
Inna Aphasizheva, Ruslan Aphasizhev
Published Online: Dec 16 2020
DOI:10.1002/wrna.1638

Abstract Full article on Wiley Online Library:   HTML | PDF
The multifaceted eukaryotic cap structure

Advanced Review
Jerry Pelletier, T. Martin Schmeing, Nahum Sonenberg
Published Online: Dec 09 2020
DOI:10.1002/wrna.1636

Abstract Full article on Wiley Online Library:   HTML | PDF
Intron retention and its impact on gene expression and protein diversity: A review and a practical guide

Advanced Review
William Ritchie, Marie‐Louise Hammarskjold, David Rekosh, Bandana Kumari, Lucile Broseus, David F. Grabski
Published Online: Oct 18 2020
DOI:10.1002/wrna.1631

Abstract Full article on Wiley Online Library:   HTML | PDF
microRNA strand selection: Unwinding the rules

Advanced Review
Jeffrey C. Medley, Ganesh Panzade, Anna Y. Zinovyeva
Published Online: Sep 20 2020
DOI:10.1002/wrna.1627

Abstract Full article on Wiley Online Library:   HTML | PDF
RNA structures in alternative splicing and back‐splicing

Advanced Review
Yongfeng Jin, Yijun Meng, Bingbing Xu
Published Online: Sep 14 2020
DOI:10.1002/wrna.1626

Abstract Full article on Wiley Online Library:   HTML | PDF
Diverse functions of deadenylases in DNA damage response and genomic integrity

Advanced Review
Yong‐Bin Yan
Published Online: Aug 13 2020
DOI:10.1002/wrna.1621

Abstract Full article on Wiley Online Library:   HTML | PDF
Functions and mechanisms of RNA tailing by metazoan terminal nucleotidyltransferases

Advanced Review
Vladyslava Liudkovska, Andrzej Dziembowski
Published Online: Jul 22 2020
DOI:10.1002/wrna.1622

Abstract Full article on Wiley Online Library:   HTML | PDF
A birds'‐eye view of the activity and specificity of the mRNA m6A methyltransferase complex

Advanced Review
David Garcias Morales, José L. Reyes
Published Online: Jul 19 2020
DOI:10.1002/wrna.1618

Abstract Full article on Wiley Online Library:   HTML | PDF
The multifaceted role of PARP1 in RNA biogenesis

Advanced Review
Rebekah Eleazer, Yvonne N. Fondufe‐Mittendorf
Published Online: Jul 12 2020
DOI:10.1002/wrna.1617

Abstract Full article on Wiley Online Library:   HTML | PDF
Two sides of the same medal: Noncoding mutations reveal new pathological mechanisms and insights into the regulation of gene expression

Advanced Review
Jens Bohne, Amelie S. Wachs
Published Online: Jul 06 2020
DOI:10.1002/wrna.1616

Abstract Full article on Wiley Online Library:   HTML | PDF
tRNA methylation: An unexpected link to bacterial resistance and persistence to antibiotics and beyond

Advanced Review
Ya‐Ming Hou, Isao Masuda, Leonard J. Foster
Published Online: Jun 13 2020
DOI:10.1002/wrna.1609

Abstract Full article on Wiley Online Library:   HTML | PDF
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