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WIREs RNA
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Splicing Regulation/Alternative Splicing

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Intron retention and its impact on gene expression and protein diversity: A review and a practical guide

Advanced Review
David F. Grabski, Lucile Broseus, Bandana Kumari, David Rekosh, Marie‐Louise Hammarskjold, William Ritchie
Published Online: Oct 18 2020
DOI:10.1002/wrna.1631

Abstract Full article on Wiley Online Library:   HTML | PDF
RNA structures in alternative splicing and back‐splicing

Advanced Review
Bingbing Xu, Yijun Meng, Yongfeng Jin
Published Online: Sep 14 2020
DOI:10.1002/wrna.1626

Abstract Full article on Wiley Online Library:   HTML | PDF
The multifaceted role of PARP1 in RNA biogenesis

Advanced Review
Yvonne N. Fondufe‐Mittendorf, Rebekah Eleazer
Published Online: Jul 12 2020
DOI:10.1002/wrna.1617

Abstract Full article on Wiley Online Library:   HTML | PDF
Two sides of the same medal: Noncoding mutations reveal new pathological mechanisms and insights into the regulation of gene expression

Advanced Review
Amelie S. Wachs, Jens Bohne
Published Online: Jul 06 2020
DOI:10.1002/wrna.1616

Abstract Full article on Wiley Online Library:   HTML | PDF
Transcription and splicing: A two‐way street

Advanced Review
Michael Tellier, Isabella Maudlin, Shona Murphy
Published Online: Mar 03 2020
DOI:10.1002/wrna.1593

Abstract Full article on Wiley Online Library:   HTML | PDF
Alternative splicing programming of axon formation

Advanced Review
Sika Zheng
Published Online: Jan 10 2020
DOI:10.1002/wrna.1585

Abstract Full article on Wiley Online Library:   HTML | PDF
What is the switch for coupling transcription and splicing? RNA Polymerase II C‐terminal domain phosphorylation, phase separation and beyond

Advanced Review
Shinichi Nakagawa, Hiroshi Maita
Published Online: Nov 03 2019
DOI:10.1002/wrna.1574

Abstract Full article on Wiley Online Library:   HTML | PDF
Fusion transcripts: Unexploited vulnerabilities in cancer?

Opinion
Natasha J. Caplen, Soumya Sundara Rajan, Carla Neckles
Published Online: Aug 13 2019
DOI:10.1002/wrna.1562

Abstract Full article on Wiley Online Library:   HTML | PDF
Pat1 RNA‐binding proteins: Multitasking shuttling proteins

Advanced Review
Caroline Vindry, Dominique Weil, Nancy Standart
Published Online: Jun 24 2019
DOI:10.1002/wrna.1557

Abstract Full article on Wiley Online Library:   HTML | PDF
Viral modulation of cellular RNA alternative splicing: A new key player in virus–host interactions?

Advanced Review
Simon Boudreault, Patricia Roy, Guy Lemay, Martin Bisaillon
Published Online: Apr 29 2019
DOI:10.1002/wrna.1543

Abstract Full article on Wiley Online Library:   HTML | PDF
Splicing and neurodegeneration: Insights and mechanisms

Advanced Review
Sara Nik, Teresa V. Bowman
Published Online: Mar 20 2019
DOI:10.1002/wrna.1532

Abstract Full article on Wiley Online Library:   HTML | PDF
Splicing and cancer: Challenges and opportunities

Advanced Review
Patricia P. Coltri, Maria G.P. dos Santos, Guilherme H.G. da Silva
Published Online: Feb 17 2019
DOI:10.1002/wrna.1527

Abstract Full article on Wiley Online Library:   HTML | PDF
Environmental influences on RNA processing: Biochemical, molecular and genetic regulators of cellular response

Advanced Review
Athma A. Pai, Francesca Luca
Published Online: Sep 14 2018
DOI:10.1002/wrna.1503

Abstract Full article on Wiley Online Library:   HTML | PDF
Glycogen synthase kinase‐3 and alternative splicing

Advanced Review
Peter S. Klein, Xiaolei Liu
Published Online: Aug 17 2018
DOI:10.1002/wrna.1501

Abstract Full article on Wiley Online Library:   HTML | PDF
RNA methylation in nuclear pre‐mRNA processing

Advanced Review
Stepanka Vanacova, Marek Bartosovic, Helena Covelo‐Molares
Published Online: Jun 19 2018
DOI:10.1002/wrna.1489

Abstract Full article on Wiley Online Library:   HTML | PDF
The evolution of posttranscriptional regulation

Advanced Review
Bernhard Schaefke, Wei Sun, Yi‐Sheng Li, Liang Fang, Wei Chen
Published Online: May 31 2018
DOI:10.1002/wrna.1485

Abstract Full article on Wiley Online Library:   HTML | PDF
Alternative‐splicing defects in cancer: Splicing regulators and their downstream targets, guiding the way to novel cancer therapeutics

Advanced Review
Laura M. Urbanski, Nathan Leclair, Olga Anczuków
Published Online: Apr 25 2018
DOI:10.1002/wrna.1476

Abstract Full article on Wiley Online Library:   HTML | PDF
Intron retention in viruses and cellular genes: Detention, border controls and passports

Advanced Review
David Rekosh, Marie‐Louise Hammarskjold
Published Online: Mar 06 2018
DOI:10.1002/wrna.1470

Abstract Full article on Wiley Online Library:   HTML | PDF
Circadian processes in the RNA life cycle

Advanced Review
Manon Torres, Denis Becquet, Jean‐Louis Franc, Anne‐Marie François‐Bellan
Published Online: Feb 09 2018
DOI:10.1002/wrna.1467

Abstract Full article on Wiley Online Library:   HTML | PDF
Mutually exclusive alternative splicing of pre‐mRNAs

Advanced Review
Yongfeng Jin, Haiyang Dong, Yang Shi, Lina Bian
Published Online: Feb 09 2018
DOI:10.1002/wrna.1468

Abstract Full article on Wiley Online Library:   HTML | PDF
Emerging roles of RNA‐binding proteins in diabetes and their therapeutic potential in diabetic complications

Advanced Review
Curtis A. Nutter, Muge N. Kuyumcu‐Martinez
Published Online: Dec 27 2017
DOI:10.1002/wrna.1459

Abstract Full article on Wiley Online Library:   HTML | PDF
Rules and tools to predict the splicing effects of exonic and intronic mutations

Advanced Review
Akio Masuda, Jun‐ichi Takeda, Kinji Ohno
Published Online: Sep 26 2017
DOI:10.1002/wrna.1451

Abstract Full article on Wiley Online Library:   HTML | PDF
An emerging model organism Caenorhabditis elegans for alternative pre‐mRNA processing in vivo

Advanced Review
Hidehito Kuroyanagi, Shotaro Wani
Published Online: Jul 13 2017
DOI:10.1002/wrna.1428

Abstract Full article on Wiley Online Library:   HTML | PDF
Chimeric RNAs in cancer and normal physiology

Advanced Review
Katarzyna Chwalenia, Loryn Facemire, Hui Li
Published Online: Jun 07 2017
DOI:10.1002/wrna.1427

Abstract Full article on Wiley Online Library:   HTML | PDF
Microexons: discovery, regulation, and function

Advanced Review
Dmytro Ustianenko, Sebastien M. Weyn‐Vanhentenryck, Chaolin Zhang
Published Online: Feb 11 2017
DOI:10.1002/wrna.1418

Abstract Full article on Wiley Online Library:   HTML | PDF
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