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WIREs Forensic Sci

An examination of aspects of the probabilistic genotyping tool: Forensic Statistical Tool

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Abstract The probabilistic genotyping software Forensic Statistical Tool implements a semi‐continuous model for DNA interpretation. This software omits any locus where the sum of the allele probabilities equals or exceeds .97. There has been criticism that this function is neither signaled by the software nor disclosed in publications. We investigate the effect of this function by creating a near clone of the model and applying it to five‐ and six‐allele loci for three‐person mixtures created in the expected population proportions. On average, the dropping of a locus is conservative for six‐peak loci and nonconservative for five‐peak loci. For persons of interest (POIs) with rare alleles, the dropping is usually conservative. For POIs with common alleles, the dropping of the locus is often nonconservative. This article is categorized under: Forensic Biology > Interpretation of Biological Evidence Forensic Biology > Forensic DNA Technologies Jurisprudence and Regulatory Oversight > Expert Evidence and Narrative
Distribution of the log10 LRs for the six‐peak loci (left) and five‐peak loci (right) averaged across loci and ethnic groups
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Jurisprudence and Regulatory Oversight > Expert Evidence and Narrative
Forensic Biology > Forensic DNA Technologies
Forensic Biology > Interpretation of Biological Evidence

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