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WIREs Nanomed Nanobiotechnol
Impact Factor: 7.689

Cell‐targeting and cell‐penetrating peptides for delivery of therapeutic and imaging agents

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Abstract This review will discuss the basic concepts concerning the use of cell‐targeting peptides (CTPs) and cell‐penetrating peptides (CPPs) in the context of nanocarrier technology. It deals with the discovery and subsequent evolution of CTPs and CPPs, issues concerning their interactions with cells and their biodistribution in vivo, and their potential advantages and disadvantages as delivery agents. The article also briefly discusses several specific examples of the use of CTPs or CPPs to assist in the delivery of nanoparticles, liposomes, and other nanocarriers. © 2009 John Wiley & Sons, Inc. This article is categorized under: Therapeutic Approaches and Drug Discovery > Emerging Technologies

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