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WIREs RNA
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Virus-Host Interactions: The RNA Perspective

RNA and RNA biology play major roles in the replication and pathology associated with viral infections. Thus we invite you to step back and think about viral infections not as a classic virologist or pathologist, but rather as an RNA biologist.

This collection contains articles that will provide you with background and insights into three aspects of the RNA biology of viral infections. First, there is a discussion of how RNA viruses interface with the various RNA machineries of the infected cell. We invite you to start by reading the overview provided by Cross et al., and then delve into the specialized aspects of cellular biology such as splicing, translation, RNA modification, RNA binding proteins and small RNA cell-cell communication.

Next, we invite you to explore the role of RNA in the cell’s antiviral response with our articles on viral piRNA responses, 2’5’ oligo A synthesis/interferon and TRIM25. Finally, if you want to examine things from the viewpoint of the RNA viruses themselves, check out the articles on RNA-only viroid pathogens and flavivirus replication.


RNA regulatory processes in RNA virus biology
Advanced Review
WIREs WIREs RNA
Published Online: Apr 29 2019
DOI: 10.1002/wrna.1536
Abstract Full article on Wiley Online Library:   HTML | PDF
Viral modulation of cellular RNA alternative splicing: A new key player in virus–host interactions?
Advanced Review
WIREs WIREs RNA
Published Online: Apr 29 2019
DOI: 10.1002/wrna.1543
Abstract Full article on Wiley Online Library:   HTML | PDF
Intron retention in viruses and cellular genes: Detention, border controls and passports
Advanced Review
WIREs WIREs RNA
Published Online: Mar 06 2018
DOI: 10.1002/wrna.1470
Abstract Full article on Wiley Online Library:   HTML | PDF
Viral internal ribosomal entry sites: four classes for one goal
Advanced Review
WIREs WIREs RNA
Published Online: Nov 29 2017
DOI: 10.1002/wrna.1458
Abstract Full article on Wiley Online Library:   HTML | PDF
Translational control during poxvirus infection
Focus Article
WIREs WIREs RNA
Published Online: Oct 31 2018
DOI: 10.1002/wrna.1515
Abstract Full article on Wiley Online Library:   HTML | PDF
Epitranscriptomic marks: Emerging modulators of RNA virus gene expression
Advanced Review
WIREs WIREs RNA
Published Online: Nov 06 2019
DOI: 10.1002/wrna.1576
Abstract Full article on Wiley Online Library:   HTML | PDF
Unconventional RNA‐binding proteins step into the virus–host battlefront
Advanced Review
WIREs WIREs RNA
Published Online: Aug 09 2018
DOI: 10.1002/wrna.1498
Abstract Full article on Wiley Online Library:   HTML | PDF
Extracellular RNA in viral–host interactions: Thinking outside the cell
Advanced Review
WIREs WIREs RNA
Published Online: Apr 08 2019
DOI: 10.1002/wrna.1535
Abstract Full article on Wiley Online Library:   HTML | PDF
PIWI pathway against viruses in insects
Advanced Review
WIREs WIREs RNA
Published Online: Jun 10 2019
DOI: 10.1002/wrna.1555
Abstract Full article on Wiley Online Library:   HTML | PDF
RNA regulation of the antiviral protein 2′‐5′‐oligoadenylate synthetase
Focus Article
WIREs WIREs RNA
Published Online: Apr 15 2019
DOI: 10.1002/wrna.1534
Abstract Full article on Wiley Online Library:   HTML | PDF
TRIM25 and its emerging RNA‐binding roles in antiviral defense
Advanced Review
WIREs WIREs RNA
Published Online: Jan 28 2020
DOI: 10.1002/wrna.1588
Abstract Full article on Wiley Online Library:   HTML | PDF
Current overview on viroid–host interactions
Advanced Review
WIREs WIREs RNA
Published Online: Oct 22 2019
DOI: 10.1002/wrna.1570
Abstract Full article on Wiley Online Library:   HTML | PDF
Organization of the Flavivirus RNA replicase complex
Advanced Review
WIREs WIREs RNA
Published Online: Aug 16 2017
DOI: 10.1002/wrna.1437
Abstract Full article on Wiley Online Library:   HTML | PDF

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