The cover image is based on the Overview Hydrogen Bond Design Principles by Ranjita Das et al., https://doi.org/10.1002/wcms.1477

Hydrogen bonds are chemical interactions that can bind molecules and molecular fragments together to create elaborate structures and functions. In the past 30 years, many hydrogen bond design principles have emerged, and together they propel the field of supramolecular chemistry.

The recently developed Principal Interacting Orbital analysis provides a bridge between chemical intuition and theoretical rigor for interfragment orbital interactions.

QSAR methods allow for a deep analysis of a library of molecules, selecting those with not only the optimal activity, but also the most favorable pharmacokinetic and toxicological profiles, which is a cost‐effective approach to obtain new treatments against increasingly resistant bacteria.

adcc: A versatile toolkit for research and teaching in computational spectroscopy based on the algebraic‐diagrammatic construction scheme for the polarization propagator (ADC).