Marina A. Dobrovolskaia, Mark Bathe
Published Online: Jul 15 2020
DOI: 10.1002/wnan.1657
Virus‐like nucleic acid nanoparticles can be programmed to deliver and release CRISPR RNPs, HDR templates, and siRNAs either alone, or in combination, for next‐generation in vivo gene therapeutic applications.
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Guobin Hong, Yu Chen, Luodan Yu, Lining Sun, Wenjuan Li, Lile Dong
Published Online: Aug 18 2020
DOI: 10.1002/wnan.1663
energy‐converting biomaterials (ECBs) for cancer therapy.
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Thirumala Govender, Usri H. Ibrahim, Mohammed Salih, Sifiso Makhathini, Victoria Oluwaseun Fasiku, Nawras Osman, Nikita Devnarain
Published Online: Aug 17 2020
DOI: 10.1002/wnan.1664
Intrinsic stimuli‐responsive nanocarriers have gained significant interest in the antibacterial research field. In this review, we discuss the potential of these nanocarriers for improved antibacterial drug delivery and highlight further research required to optimize their potential.
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René Roy, Serge Mignani, Leila Mousavifar, Tze Chieh Shiao, Serge Moffett
Published Online: Aug 10 2020
DOI: 10.1002/wnan.1659
Families of nanoparticles have been readily modified with biologically active carbohydrate moieties.
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Nishir Mehta, Sushant P. Sahu, Shahensha Shaik, Ram Devireddy, Manas Ranjan Gartia
Published Online: Aug 05 2020
DOI: 10.1002/wnan.1661
Versatile use of dark‐field hyperspectral imaging for detecting transport of nanomaterials in cells and tissues and for cancer diagnostics.
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Ivan Kempson
Published Online: Jul 19 2020
DOI: 10.1002/wnan.1656
Nanoparticles can promote radiosensitization of cancer cells by physical, physico‐chemical, chemical and biological mechanisms
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Christina Dickmeis, Louisa Kauth, Ulrich Commandeur
Published Online: Jul 16 2020
DOI: 10.1002/wnan.1662
Plant virus nanoparticles are promising as hydrogel components for biomedical and personal care products as well as broader applications such as environmental remediation. Virus coat proteins can be engineered to display specific molecular cues for the bioactivation and functionalization of hydrogels, as well as influencing the mechanical behavior and stability of the hydrogel matrix.
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Zhongjun Du, Hua Shao, Martin F. Lavin, Cheng Peng, Yingwen Mu, Ziyuan Li
Published Online: Jun 29 2020
DOI: 10.1002/wnan.1658
Schematic diagram of silica nanoparticles applied to different nanomedicine.
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Rachael M. Crist, Siva Sai Krishna Dasa, Christina H. Liu, Jeffrey D. Clogston, Marina A. Dobrovolskaia, Stephan T. Stern
Published Online: Aug 23 2020
DOI: 10.1002/wnan.1665
The ideal imaging nanoparticle will avoid the mononuclear phagocytic system (liver), rapidly accumulate in target tissue by receptor‐mediated transcytosis or passive/active targeting mechanisms, and undergo renal elimination to increase signal/background.
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Yue‐Yin Pan, Da‐Bing Huang, Rui Li, Yusheng Liu, Yuhao Hao, Wei Wang
Published Online: Jul 22 2020
DOI: 10.1002/wnan.1654
Schematic of nanomedicine with cargoes inside and stabilizer or targeting ligand on surface for lung cancer treatment via inhaled or systemic administration.
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