Myriam Gorospe, Dimitrios Tsitsipatis
Published Online: Oct 28 2020
DOI: 10.1002/wrna.1633
Workflow of molecular circular RNA analysis
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William Ritchie, Marie‐Louise Hammarskjold, David Rekosh, Bandana Kumari, Lucile Broseus, David F. Grabski
Published Online: Oct 18 2020
DOI: 10.1002/wrna.1631
The many fates of mRNA with retained introns.
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Yongfeng Jin, Yijun Meng, Bingbing Xu
Published Online: Sep 14 2020
DOI: 10.1002/wrna.1626
Significant progress has been made on the identification, roles and mechanisms of RNA structures in regulating alternative‐, back‐ and trans‐splicing events.
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Tommy Alain, Adrian Pelin, Serge Neault, Huy‐Dung Hoang
Published Online: Aug 05 2020
DOI: 10.1002/wrna.1619
Translation control of mammalian cells during viral infection can be impacted by tRNA fragments, N6‐methyladenosine (m6A), or modified tRNA pools.
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David Garcias Morales, José L. Reyes
Published Online: Jul 19 2020
DOI: 10.1002/wrna.1618
m6A influences the functionality of modified transcripts to regulate gene expression at the post‐transcriptional level. A process that is considered to occur cotranscriptionally, m6A addition can be removed or specifically recognized by protein factors that will channel the modified mRNA to distinct destinations, effectively modulating its expression.
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Jens Bohne, Amelie S. Wachs
Published Online: Jul 06 2020
DOI: 10.1002/wrna.1616
A pre‐mRNA consists of many noncoding sequences which harbor regulatory potential. Mutations (red asterisks) in these motifs alter the fate of mRNAs.
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Mona Batish, Vijay Parashar, Fatu Badiane Markey
Published Online: Jun 16 2020
DOI: 10.1002/wrna.1608
Methods for spatial and temporal imaging of RNA processing at single‐molecule resolution.
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Thomas A. Cooper, Sara J. Johnson
Published Online: Nov 16 2020
DOI: 10.1002/wrna.1634
LncRNAs and expanded microsatellite RNA display extensive functional overlap. Shared mechanisms include protein sequestration, peptide translation, miRNA processing, and miRNA sequestration. Understanding parallel mechanisms shared between the two RNA species can reveal biological impact relevant to both lncRNAs and pathogenic microsatellite RNAs. (Created with BioRender.com).
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