Hannah Carter, Kivilcim Ozturk, Emidio Capriotti
Published Online: Dec 12 2018
DOI: 10.1002/wsbm.1443
Conceptual representation of genome interpretation using biological networks.
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Michael C. Reed, Janet A. Best, H. Frederik Nijhout
Published Online: Oct 29 2018
DOI: 10.1002/wsbm.1440
Homeostatic mechanism stabilize phenotypes against genetic and environmental variation. This show stability of extracellular serotonin against genetic variation in tryptophan hydroxylase (TPH) and the serotonin reuptake transporter (SERT). Genetic polymorphisms (white circles) have a large effect at the functional level (enzyme activity) but little effect at the phenotypic level.
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